Risks of Novel Coronavirus Disease (COVID-19) in Pregnancy; a Narrative Review
Archives of Academic Emergency Medicine,
Vol. 8 No. 1 (2020),
,
Page e34
https://doi.org/10.22037/aaem.v8i1.595
Abstract
Introduction: The outbreak of the new Coronavirus in China in December 2019 and subsequently in various countries around the world has raised concerns about the possibility of vertical transmission of the virus from mother to fetus. The present study aimed to review published literature in this regard.
Methods: In this narrative review, were searched for all articles published in various databases including PubMed, Scopus, Embase, Science Direct, and Web of Science using MeSH-compliant keywords including COVID-19, Pregnancy, Vertical transmission, Coronavirus 2019, SARS-CoV-2 and 2019-nCoV from December 2019 to March 18, 2020 and reviewed them. All type of articles published about COVID-19 and vertical transmission in pregnancy were included.
Results: A review of 13 final articles published in this area revealed that COVID-19 can cause fetal distress, miscarriage, respiratory distress and preterm delivery in pregnant women but does not infect newborns. There has been no report of vertical transmission in pregnancy, and it has been found that clinical symptoms of COVID-19 in pregnant women are not different from those of non-pregnant women.
Conclusion: Overall, due to lack of appropriate data about the effect of COVID-19 on pregnancy, it is necessary to monitor suspected pregnant women before and after delivery. For confirmed cases both the mother and the newborn child should be followed up comprehensively.
- COVID-19
- pregnancy
- infectious disease transmission
- vertical
- coronavirus
- severe acute respiratory syndrome coronavirus
How to Cite
References
McIntosh K, Hirsch MS, Bloom A. Coronavirus disease 2019 (COVID-19).
Qiao J. What are the risks of COVID-19 infection in pregnant women? The Lancet. 2020.
Mardani M, Pourkaveh B. A Controversial Debate: Vertical Transmission of COVID-19 in Pregnancy. Neoscriber Demo Publisher.
Rasmussen SA, Smulian JC, Lednicky JA, Wen TS, Jamieson DJ. Coronavirus Disease 2019 (COVID-19) and Pregnancy: What obstetricians need to know. American Journal of Obstetrics and Gynecology. 2020.
Tavakoli A, Vahdat K, Keshavarz M. Novel Coronavirus Disease 2019 (COVID-19): An Emerging Infectious Disease in the 21st Century. ISMJ. 2020;22(6):432-50.
Organization WH. Coronavirus disease 2019 (COVID-19) Situation Report – 60 2020 [updated March 16, 2020; cited 2020]. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports/.
Yang P, Liu P, Li D, Zhao D. Corona Virus Disease 2019, a growing threat to children? Journal of Infection. 2020.
Yu A, Wang Z, Ren W, Wu Z, Hu Z, Li L, et al. Epidemic analysis of COVID-19 in China after Wuhan was restricted.
Zu ZY, Jiang MD, Xu PP, Chen W, Ni QQ, Lu GM, et al. Coronavirus Disease 2019 (COVID-19): A Perspective from China. Radiology. 2020:200490.
Jiang F, Deng L, Zhang L, Cai Y, Cheung CW, Xia Z. Review of the Clinical Characteristics of Coronavirus Disease 2019 (COVID-19). Journal of General Internal Medicine. 2020:1-5.
Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. New England Journal of Medicine. 2020.
Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. The Lancet. 2020.
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet. 2020;395(10223):497-506.
Organization. WH. Novel coronavirus situation report -2. January 22, 2020. Available from: https://w ww.who.int/docs/default-source/coronaviruse/situation-reports/20200122-sitrep-2-2019-ncov. pdf (Accessed on January 23, 2020).
Wang X, Zhou Z, Zhang J, Zhu F, Tang Y, Shen X. A case of 2019 Novel Coronavirus in a pregnant woman with preterm delivery. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America. 2020.
Liu W, Wang Q, Zhang Q, Chen L, Chen J, Zhang B, et al. Coronavirus Disease 2019 (COVID-19) During Pregnancy: A Case Series. 2020.
Liu D, Li L, Wu X, Zheng D, Wang J, Liang B, et al. Pregnancy and Perinatal Outcomes of Women with COVID-19 Pneumonia: A Preliminary Analysis. Available at SSRN 3548758. 2020.
Chua MSQ, Lee JCS, Sulaiman S, Tan HK. From the frontlines of COVIDâ€19–How prepared are we as obstetricians: a commentary. BJOG: An International Journal of Obstetrics & Gynaecology. 2020.
Lu Q, Shi Y. Coronavirus disease (COVIDâ€19) and neonate: What neonatologist need to know. Journal of Medical Virology. 2020.
Liang H, Acharya G. Novel corona virus disease (COVIDâ€19) in pregnancy: What clinical recommendations to follow? Acta Obstetricia et Gynecologica Scandinavica. 2020.
Favre G, Pomar L, Musso D, Baud D. 2019-nCoV epidemic: what about pregnancies? The Lancet. 2020;395(10224):e40.
DA S, AL. G. Potential Maternal and Infant Outcomes from (Wuhan) Coronavirus 2019-nCoV Infecting Pregnant Women: Lessons from SARS, MERS, and Other Human Coronavirus Infections. Viruses. 2020;12(2):1-16.
Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. 2020.
Zhu H, Wang L, Fang C, Peng S, Zhang L, Chang G. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr. 2020;9(1):51-60.
Lam CM, Wong SF, Leung TN, Chow KM, Yu WC, Wong TY, et al. A caseâ€controlled study comparing clinical course and outcomes of pregnant and nonâ€pregnant women with severe acute respiratory syndrome. BJOG: An International Journal of Obstetrics & Gynaecology. 2004;111(8):771-4.
Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet. 2020;395(10223):507-13.
Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus–infected pneumonia. New England Journal of Medicine. 2020.
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