Ultrasonography in Detection of Renal Calculi in Children; a Systematic Review and Meta-analysis
Archives of Academic Emergency Medicine,
Vol. 7 No. 1 (2019),
1 January 2019
,
Page e66
https://doi.org/10.22037/aaem.v7i1.485
Abstract
Introduction: Although numerous studies have been done to evaluate the diagnostic value of ultrasonography in diagnosis of renal calculi in children, there is still no consensus. Therefore, in the present systematic review and meta-analysis, we aimed to evaluate the diagnostic accuracy of ultrasonography in identifying renal stones in children.
Methods: A comprehensive search of the electronic databases including Medline, Embase, Scopus and Web of Science was conducted up to July 2019. Diagnostic accuracy studies in children were included. Data was summarized and pooled. Area under the curve (AUC), sensitivity, specificity, diagnostic score and diagnostic odds ratio were reported with 95% confidence interval (95% CI).
Results: Data from 7 articles were included. Pooled analysis showed that the area under the curve of ultrasonography in diagnosis of pediatric renal calculi was 0.94 (95% CI: 0.92 to 0.96). The sensitivity and specificity of this diagnostic modality were 0.80 (95% CI: 0.70 to 0.87) and 1.00 (95% CI: 0.84 to 1.00), respectively. Diagnostic score and diagnostic odds ratio of ultrasonography in detection of renal calculi were 110.32 (95% CI: 2.88 to 19.76) and 82362.41 (95% CI: 17.80 to 3.8 × 108), respectively.
Conclusion: Overall, the low level of evidence indicates that sensitivity and specificity of ultrasonography in detecting renal calculi in children are 80% and 100%, respectively. However, due to the serious limitations of the included studies, well-designed prospective diagnostic accuracy studies are recommended for future studies.
- Kidney calculi
- ultrasonography
- diagnostic imaging
- pediatrics
How to Cite
References
Routh JC, Graham DA, Nelson CP. Epidemiological Trends in Pediatric Urolithiasis at United States Freestanding Pediatric Hospitals. Journal of Urology. 2010;184(3):1100-5.
Lumbreras B, Donat L, Hernández-Aguado I. Incidental findings in imaging diagnostic tests: a systematic review. British Journal of Radiology. 2010;83(988):276-89.
Preston DL, Ron E, Tokuoka S, Funamoto S, Nishi N, Soda M, et al. Solid Cancer Incidence in Atomic Bomb Survivors: 1958–1998. Radiation Research. 2007;168(1):1-64.
Pearce MS, Salotti JA, Little MP, McHugh K, Lee C, Kim KP, et al. Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study. Lancet. 2012;380(9840):499-505.
Mathews JD, Forsythe AV, Brady Z, Butler MW, Goergen SK, Byrnes GB, et al. Cancer risk in 680 000 people exposed to computed tomography scans in childhood or adolescence: data linkage study of 11 million Australians. BMJ. 2013;346(may21 1):f2360-f1.
McGahan JP, Wang L, Richards JR. From the RSNA Refresher Courses. RadioGraphics. 2001;21(suppl_1):S191-S9.
Poletti PA, Kinkel K, Vermeulen B, Irmay F, Unger P-F, Terrier F. Blunt Abdominal Trauma: Should US Be Used to Detect Both Free Fluid and Organ Injuries? Radiology. 2003;227(1):95-103.
Poletti PA, Mirvis SE, Shanmuganathan K, Takada T, Killeen KL, Perlmutter D, et al. Blunt Abdominal Trauma Patients: Can Organ Injury Be Excluded without Performing Computed Tomography? Journal of Trauma. 2004;57(5):1072-81.
Hauger O, Bonnefoy O, Moinard M, Bersani D, Diard F. Occult Fractures of the Waist of the Scaphoid. American Journal of Roentgenology. 2002;178(5):1239-45.
Herneth AM, Siegmeth A, Bader TR, Ba-Ssalamah A, Lechner G, Metz VM, et al. Scaphoid Fractures: Evaluation with High-Spatial-Resolution US—Initial Results. Radiology. 2001;220(1):231-5.
Ferrar L, Roux C, Felsenberg D, Glüer CC, Eastell R. Association between incident and baseline vertebral fractures in European women: vertebral fracture assessment in the Osteoporosis and Ultrasound Study (OPUS). Osteoporosis International. 2011;23(1):59-65.
Platon A, Poletti P-A, Van Aaken J, Fusetti C, Della Santa D, Beaulieu J-Y, et al. Occult fractures of the scaphoid: the role of ultrasonography in the emergency department. Skeletal Radiology. 2011;40(7):869-75.
Kelloff J, Hulett R, Spivey M. Acute rib fracture diagnosis in an infant by US: a matter of child protection. Pediatric Radiology. 2008;39(1):70-2.
Simanovsky N, Lamdan R, Hiller N, Simanovsky N. Sonographic Detection of Radiographically Occult Fractures in Pediatric Ankle and Wrist Injuries. Journal of Pediatric Orthopaedics. 2009;29(2):142-5.
Hoppe B, Kemper MJ. Diagnostic examination of the child with urolithiasis or nephrocalcinosis. Pediatric Nephrology. 2008;25(3):403-13.
Yen K, Gorelick MH. Ultrasound applications for the pediatric emergency department: A review of the current literature. Pediatric Emergency Care. 2002;18(3):226-34.
Tasian GE, Copelovitch L. Evaluation and Medical Management of Kidney Stones in Children. Journal of Urology. 2014;192(5):1329-36.
Rosa M, Usai P, Miano R, Kim FJ, Agrò EF, Bove P, et al. Recent finding and new technologies in nephrolithiasis: a review of the recent literature. BMC Urology. 2013;13(1).
Kokorowski PJ, Hubert K, Nelson CP. Evaluation of pediatric nephrolithiasis. Indian Journal of Urology. 2010;26(4):531-5.
Whiting PF. QUADAS-2: A Revised Tool for the Quality Assessment of Diagnostic Accuracy Studies. Annals of Internal Medicine. 2011;155(8):529.
Higgins JPT. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557-60.
Hu P, Lu L, Qin YH, Hu B. Utility of CT Scan in detection of melamine--associated urinary stones. Indian journal of pediatrics. 2010;77(12):1405-8.
Johnson EK, Faerber GJ, Roberts WW, Wolf JS, Jr., Park JM, Bloom DA, et al. Are stone protocol computed tomography scans mandatory for children with suspected urinary calculi? Urology. 2011;78(3):662-6.
Palmer JS, Donaher ER, O'Riordan MA, Dell KM. Diagnosis of pediatric urolithiasis: role of ultrasound and computerized tomography. The Journal of urology. 2005;174(4 Pt 1):1413-6.
Passerotti C, Chow JS, Silva A, Schoettler CL, Rosoklija I, Perez-Rossello J, et al. Ultrasound versus computerized tomography for evaluating urolithiasis. The Journal of urology. 2009;182(4 Suppl):1829-34.
Roberson NP, Dillman JR, O'Hara SM, DeFoor WR, Jr., Reddy PP, Giordano RM, et al. Comparison of ultrasound versus computed tomography for the detection of kidney stones in the pediatric population: a clinical effectiveness study. Pediatric radiology. 2018;48(7):962-72.
Smith SL, Somers JM, Broderick N, Halliday K. The role of the plain radiograph and renal tract ultrasound in the management of children with renal tract calculi. Clinical radiology. 2000;55(9):708-10.
Verhagen MV, Watson TA, Hickson M, Smeulders N, Humphries PD. Acoustic shadowing in pediatric kidney stone ultrasound: a retrospective study with non-enhanced computed tomography as reference standard. Pediatric radiology. 2019;49(6):777-83.
Assimos D. Re: Are Stone Protocol Computed Tomography Scans Mandatory for Children With Suspected Urinary Calculi? Journal of Urology. 2012;187(4):1436-7.
Ebrahimi A, Yousefifard M, Kazemi HM, Rasouli HR, Asady H, Jafari AM, et al. Diagnostic accuracy of chest ultrasonography versus chest radiography for identification of pneumothorax: a systematic review and meta-analysis. Tanaffos. 2014;13(4):29.
Hosseini M, Ghelichkhani P, Baikpour M, Tafakhori A, Asady H, Ghanbari MJH, et al. Diagnostic accuracy of ultrasonography and radiography in detection of pulmonary contusion; a systematic review and meta-analysis. Emergency. 2015;3(4):127.
Rahimi-Movaghar V, Yousefifard M, Ghelichkhani P, Baikpour M, Tafakhori A, Asady H, et al. Application of ultrasonography and radiography in detection of hemothorax; a systematic review and meta-analysis. Emergency. 2016;4(3):116.
Yousefifard M, Baikpour M, Ghelichkhani P, Asady H, Darafarin A, Esfahani MRA, et al. Comparison of ultrasonography and radiography in detection of thoracic bone fractures; a systematic review and meta-analysis. Emergency. 2016;4(2):55.
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