The Effect of Aromatherapy with Lavender on Pain of Needle Insertion and Severity of Restless Legs Syndrome in Hemodialysis Patients; a Systematic Review and Meta-analysis
Archives of Academic Emergency Medicine,
Vol. 12 No. 1 (2024),
1 January 2024
,
Page e4
https://doi.org/10.22037/aaem.v12i1.2071
Abstract
Introduction: Pain experienced during the insertion of a catheter into the arteriovenous fistula (AVF) and restless legs syndrome (RLS) are prevalent issues among Hemodialysis (HD) patients. The primary objective of this systematic review and meta-analysis was to consolidate the findings from randomized clinical trial (RCT) studies examining the impact of aromatherapy with lavender on the pain associated with AVF catheter insertion and RLS in HD patients.
Methods: A systematic search was conducted on PubMed, Web of Science, Scopus, Cochrane, Embase, ClinicalTrials.gov, and Google Scholar search engine from inception to August 1, 2022, using keywords extracted from Medical Subject Headings, such as “Aromatherapy”, “Lavender”, “Arteriovenous fistula”, “Pain”, “Restless legs syndrome”, and “Hemodialysis”.
Results: Finally, eleven articles were included in this systematic review and meta-analysis. The results showed that aromatherapy reduced the average pain of catheter insertion in AVF compared to the control group (Standard Mean Difference: -1.60, 95% Confidence Interval: -2.32 to -0.87, Z=4.32, I2:90.3%, P<0.001). Also, aromatherapy massage reduced the average severity of RLS compared to the control group, which was statistically significant (Weighted Mean Difference: -13.21, 95% Confidence Interval: -17.50 to -8.91, Z=6.03, I2:93.0%, P<0.001). Also, the subgroup analysis showed that lavender in the intervention group significantly decreased the pain intensity compared to the "no intervention" group (P<0.001), yet it was not significant compared to the placebo group (P=0.12).
Conclusion: In summary, the findings indicate a notable reduction in catheter insertion pain in AVF and relief from RLS among HD patients through the use of lavender essential oil. As a result, future research is encouraged to include a comparison of lavender's effects with those of a placebo group.
- Aromatherapy
- lavender
- pain
- arteriovenous fistula
- restless legs syndrome
- massage therapy
How to Cite
References
Gansevoort RT, Correa-Rotter R, Hemmelgarn BR, Jafar TH, Heerspink HJL, Mann JF, et al. Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention. Lancet. 2013;382(9889):339-52.
Hill NR, Fatoba ST, Oke JL, Hirst JA, O’Callaghan CA, Lasserson DS, et al. Global Prevalence of Chronic Kidney Disease – A Systematic Review and Meta-Analysis. PLOS ONE. 2016;11(7):e0158765.
Eckardt K-U, Coresh J, Devuyst O, Johnson RJ, Köttgen A, Levey AS, et al. Evolving importance of kidney disease: from subspecialty to global health burden. Lancet. 2013;382(9887):158-69.
Alzaatreh MY, Abdalrahim MS. Management strategies for pain associated with arteriovenous fistula cannulation: an integrative literature review. Hemodial Int. 2020;24(1):3-11.
Sabitha P, Khakha D, Mahajan S, Gupta S, Agarwal M, Yadav S. Effect of cryotherapy on arteriovenous fistula puncture-related pain in hemodialysis patients. Indian J Nephrol. 2008;18(4):155-8.
Figueiredo AE, Viegas A, Monteiro M, Poli‐de‐Figueiredo CE. Research into pain perception with arteriovenous fistula (avf) cannulation. J Ren Care. 2008;34(4):169-72.
Ghods AA, Abforosh NH, Ghorbani R, Asgari MR. The effect of topical application of lavender essential oil on the intensity of pain caused by the insertion of dialysis needles in hemodialysis patients: a randomized clinical trial. Complement Ther Med. 2015;23(3):325-30.
Quinn R, Lamping D, Lok C, Meyer R, Hiller J, Lee J, et al. The Vascular Access Questionnaire: assessing patient-reported views of vascular access. J Vasc Access. 2008;9(2):122-8.
Hashemi SH, Hajbagheri A, Aghajani M. The effect of massage with lavender oil on restless leg syndrome in hemodialysis patients: a randomized controlled trial. Nurs Midwifery Stud. 2015;4(4):e29617.
Kim J-M, Kwon H-M, Lim CS, Kim YS, Lee S-J, Nam H. Restless legs syndrome in patients on hemodialysis: symptom severity and risk factors. J Clin Neurol. 2008;4(4):153-7.
Mucsi I, Molnar MZ, Ambrus C, Szeifert L, Kovacs AZ, Zoller R, et al. Restless legs syndrome, insomnia and quality of life in patients on maintenance dialysis. Nephrol Dial Transplant. 2005;20(3):571-7.
Bourbonnais FF, Tousignant KF. The pain experience of patients on maintenance hemodialysis. Nephrol Nurs J. 2012;39(1):13-9.
Wang QT, Wei L, Luo YM, Lin LJ, Deng C, Hu P, et al. Effectiveness of Aromatherapy on Ameliorating Fatigue in Adults: A Meta-Analysis. Evid Based Complement Alternat Med. 2022:1141411.
Song X, Peng J, Jiang W, Ye M, Jiang L. Effects of aromatherapy on sleep disorders: A protocol for systematic review and meta-analysis. Medicine. 2021;100(17):e25727.
Aliasgharpour M, Abbaszadeh R, Mohammadi N, Kazemnejad A. Effect of lavender aromatherapy on the pain of arteriovenous fistula puncture in patients on hemodialysis. Nurs Pract Today. 2016;3(1):26-30.
Taşan E, Ovayolu O, Ovayolu N. The effect of diluted lavender oil inhalation on pain development during vascular access among patients undergoing haemodialysis. Complement Ther Clin Pract. 2019;35:177-82.
Ali B, Al-Wabel NA, Shams S, Ahamad A, Khan SA, Anwar F. Essential oils used in aromatherapy: A systemic review. Asian Pac J Trop Biomed. 2015;5(8):601-11.
Koulivand PH, Khaleghi Ghadiri M, Gorji A. Lavender and the nervous system. Evid Based Complement Alternat Med. 2013;2013:681304.
Farrar AJ, Farrar FC. Clinical aromatherapy. Nurs Clin. 2020;55(4):489-504.
Gok Metin Z, Arikan Donmez A, Izgu N, Ozdemir L, Arslan IE. Aromatherapy massage for neuropathic pain and quality of life in diabetic patients. J Nurs Scholarsh. 2017;49(4):379-88.
Ghasemi M, Rejeh N, Bahrami T, Heravi-Karimooi M, Tadrisi SD, Vaismoradi M. Aromatherapy massage vs. Foot reflexology on the severity of restless legs syndrome in female patients undergoing hemodialysis. Geriatrics. 2021;6(4):99.
Shirazi MTF, Karandish M. The Effect of Lavender Inhalation on the Pain Perception of Orthodontic Separator Placement: An Open-Label Randomized Controlled Trial. Tradit Integr Med. 2022;7(4):361-8.
Donelli D, Antonelli M, Bellinazzi C, Gensini GF, Firenzuoli F. Effects of lavender on anxiety: A systematic review and meta-analysis. Phytomedicine. 2019;65:153099.
Kim M, Nam ES, Lee Y, Kang H-J. Effects of lavender on anxiety, depression, and physiological parameters: Systematic review and meta-analysis. Asian Nurs Res. 2021;15(5):279-90.
Xia M, He QE, Ying GH, Fei XP, Zhou WJ, He XL. Clinical Efficacy and Safety of Massage for the Treatment of Restless Leg Syndrome in Hemodialysis Patients: A Meta-Analysis of 5 Randomized Controlled Trials. Front Psychiatry. 2022;13:843263.
Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ. 2009;339:b2535.
Corlett RT. Trouble with the gray literature. Biotropica. 2011;43(1):3-5.
Crichton N. Visual analogue scale (VAS). J Clin Nurs. 2001;10(5):706-6.
Hawker GA, Mian S, Kendzerska T, French M. Measures of adult pain: Visual analog scale for pain (vas pain), numeric rating scale for pain (nrs pain), mcgill pain questionnaire (mpq), short‐form mcgill pain questionnaire (sf‐mpq), chronic pain grade scale (cpgs), short form‐36 bodily pain scale (sf‐36 bps), and measure of intermittent and constant osteoarthritis pain (icoap). Arthritis Care Res. 2011;63(S11):S240-S52.
Higgins JPT, (editors) GS. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]: The Cochrane Collaboration; 2011.
Ajorpaz NM, Rahemi Z, Aghajani M, Hashemi SH. Effects of glycerin oil and lavender oil massages on hemodialysis patients’ restless legs syndrome. J Bodyw Mov Ther. 2020;24(1):88-92.
Amrollahi A, Rafiei A, Bahri A, Nasiriani K. Effects of aromatherapy massage on the severity of restless legs syndrome in hemodialysis patients: A randomized clinical trial. Ther Apher Dial. 2022;26(6):1131-6.
Bagheri-Nesami M, Espahbodi F, Nikkhah A, Shorofi SA, Charati JY. The effects of lavender aromatherapy on pain following needle insertion into a fistula in hemodialysis patients. Complement Ther Clin Pract. 2014;20(1):1-4.
Şahin S, Tokgöz B, Demir G. Effect of lavender aromatherapy on arteriovenous fistula puncture pain and the level of state and trait anxiety in hemodialysis patients: a randomized controlled trial. Pain Manag Nurs. 2021;22(4):509-15.
Tüzün Özdemir S, Akyol A. Effect of inhaler and topical lavender oil on pain management of arteriovenous fistula cannulation. J Vasc Access. 2023:24(3):465-474.
Oshvandi K, Mirzajani Letomi F, Soltanian AR, Shamsizadeh M. The effects of foot massage on hemodialysis patients' sleep quality and restless leg syndrome: A comparison of lavender and sweet orange essential oil topical application. J Complement Integr Med. 2021;18(4):843-50.
Ozen N, Sayilan AA, Ok E, Sayilan S, Ozen V, Sousa CN, et al. Effects of Long-term Administration of Inhaled Lavender During Hemodialysis on Patients' Invasive Pain, Anxiety, and Comfort During Cannulation: A Single-blind Randomized Controlled Trial. Altern Ther Health Med. 2023;29(2):6-12.
Steflitsch W, Steflitsch M. Clinical aromatherapy. J Mens Health. 2008;5(1):74-85.
Seyyed-Rasooli A, Salehi F, Mohammadpoorasl A, Goljaryan S, Seyyedi Z, Thomson B. Comparing the effects of aromatherapy massage and inhalation aromatherapy on anxiety and pain in burn patients: A single-blind randomized clinical trial. Burns. 2016;42(8):1774-80.
Bagheri H, Salmani T, Nourian J, Mirrezaie SM, Abbasi A, Mardani A, et al. The effects of inhalation aromatherapy using lavender essential oil on postoperative pain of inguinal hernia: a randomized controlled trial. J Perianesth Nurs. 2020;35(6):642-8.
Rositasari E, Maliya A. Lavender Aromatherapy to Treat the Symptoms of Restless Leg Syndrome in Patients Undergoing Hemodialization. Media Keperawatan Indonesia. 2022;5(2):139-46.
Oken BS. Placebo effects: clinical aspects and neurobiology. Brain. 2008;131(Pt 11):2812-23.
- Abstract Viewed: 943 times
- pdf Downloaded: 1343 times