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  4. Case Report

Vol. 10 No. 1 (2022)

January 2022

Cocaine and Volatile Nitrite–Induced Methemoglobinemia; a Case Report and Treatment Approach Review

  • Milena Ribeiro Paixão
  • Tarso Augusto Duenhas Accorsi
  • Luis Felipe Lopes Prada
  • Lucas Zoboli Pocebon
  • Karine De Amicis Lima
  • Karen Francine Köhler
  • Leandro Santini Echenique
  • José Leão de Souza Júnior

Archives of Academic Emergency Medicine, Vol. 10 No. 1 (2022), 1 January 2022 , Page e75
https://doi.org/10.22037/aaem.v10i1.1753 Published: 2022-09-21

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Abstract

Cyanosis is typically a sign of a potentially life-threatening condition in the emergency department and requires immediate workup and treatment. This case report highlights the diagnostic reasoning and clinical approach to cocaine- and volatile nitrite–induced methemoglobinemia (MHG). MHG is a rare, life-threatening cause of cyanosis. The diagnosis must be suspected in the emergency department in the presence of hypoxia and cyanosis disproportionate to cardiopulmonary repercussions and refractory to oxygen supplementation. Acquired causes are more prevalent than genetics, and recreational drugs should be highly suspected. Despite the rarity of this situation, cyanosis precipitants and the specificities of each hemoglobinopathy are reviewed in this article.

Keywords:
  • Methemoglobinemia
  • Cocaine
  • Nitrites
  • Emergency Medicine
  • Case Report
  • pdf

How to Cite

1.
Ribeiro Paixão M, Accorsi TAD, Prada LFL, Pocebon LZ, De Amicis Lima K, Köhler KF, et al. Cocaine and Volatile Nitrite–Induced Methemoglobinemia; a Case Report and Treatment Approach Review. Arch Acad Emerg Med [Internet]. 2022 Sep. 21 [cited 2026 Jul. 7];10(1):e75. Available from: https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/1753
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