Protocol Adherence for Severe Sepsis and Septic Shock Management in the Emergency Department; a Clinical Audit
Archives of Academic Emergency Medicine,
Vol. 5 No. 1 (2017),
1 January 2017
,
Page e16
https://doi.org/10.22037/aaem.v5i1.140
Abstract
Introduction: Although significant development in the field of medicine is achieved, sepsis is still a major issue threatening humans’ lives. This study was aimed to audit the management of severe sepsis and septic shock patients in emergency department (ED) according to the present standard guidelines.
Method:Â This is a prospective audit on approaching adult septic patients who were admitted to ED. The audit checklist was created based on the protocols of Surviving Sepsis Campaign and British Royal College recommendations. The mean knowledge score and the compliance rate of studied measures regarding standard protocols were calculated using SPSS version 21.
Results: 30 emergency medicine residents were audited (63.3% male). The mean knowledge score of studied residents regarding standard guidelines were 5.07 ± 1.78 (IQR = 2) in pre education and 8.17 ± 1.31 (IQR = 85) in post education phase (p < 0.001). There was excellent compliance with standard in 4 (22%) studied measures, good in 2 (11%), fair in 1 (6%), weak in 2 (11%), and poor in 9 (50%). 64% of poor compliance measures correlated to therapeutic factors. After training, score of 5 measures including checking vital signs in < 20 minute, central vein pressure measurement in < 1 hour, blood culture request, administration of vasopressor agents, and high flow O2 therapy were improved clinically, but not statistically.
Conclusion: The protocol adherence in management of severe sepsis and septic shock for urine output measurement, central venous pressure monitoring, administration of inotrope agents, blood transfusion, intravenous antibiotic and hydration therapy, and high flow O2 delivery were disappointingly low. It seems training workshops and implementation of Clinical audit can improve residents’ adherence to current standard guidelines regarding severe sepsis and septic shock.
- Sepsis
- shock
- septic
- disease management
- guideline adherence
- clinical audit
How to Cite
References
Bone RC, Balk RA, Cerra FB, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest. 1992;101(6):1644-55.
Tannehill D. Treating Severe Sepsis & Septic Shock in 2012. Journal of Blood Disorders & Transfusion. 2013;2013.
Morrell MR, Micek ST, Kollef MH. The management of severe sepsis and septic shock. Infectious disease clinics of North America. 2009;23(3):485-501.
Stearns-Kurosawa DJ, Osuchowski MF, Valentine C, Kurosawa S, Remick DG. The pathogenesis of sepsis. Annual review of pathology. 2011;6:19.
Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Critical Care Medicine-Baltimore-. 2001;29(7):1303-10.
Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. New England Journal of Medicine. 2003;348(16):1546-54.
Bennett JE, Dolin R, Blaser MJ. Principles and practice of infectious diseases: Elsevier Health Sciences; 2014.
Fauci AS. Harrison's principles of internal medicine: McGraw-Hill, Medical Publishing Division.
Russell JA. Management of sepsis. New England Journal of Medicine. 2006;355(16):1699-713.
Vincent J-L, Moreno R, Takala J, et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive care medicine. 1996;22(7):707-10.
Ferrer R, Artigas A, Levy MM, et al. Improvement in process of care and outcome after a multicenter severe sepsis educational program in Spain. Jama. 2008;299(19):2294-303.
Miller III RR, Dong L, Nelson NC, et al. Multicenter implementation of a severe sepsis and septic shock treatment bundle. American journal of respiratory and critical care medicine. 2013;188(1):77-82.
Robson W, Beavis S, Spittle N. An audit of ward nurses’ knowledge of sepsis. Nursing in Critical Care. 2007;12(2):86-92.
Dellinger RP, Levy MM, Rhodes A, et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive care medicine. 2013;39(2):165-228.
Dellinger R, Carlet J, Masur H, et al. Surviving Sepsis Campaign Management Guidelines Committee: Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Crit Care Med. 2004;32(3):858-73.
Dellinger RP, Levy MM, Carlet JM, et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive care medicine. 2008;34(1):17-60.
Catenacci MH, King K. Severe sepsis and septic shock: improving outcomes in the emergency department. Emergency medicine clinics of North America. 2008;26(3):603-23.
Kumar A, Roberts D, Wood KE, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Critical care medicine. 2006;34(6):1589-96.
Leibovici L, Shraga I, Drucker M, Konigsberger H, Samra Z, Pitlik S. The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection. JOURNAL OF INTERNAL MEDICINE-OXFORD-. 1998;244:379-86.
Inwald DP, Tasker RC, Peters MJ, Nadel S. Emergency management of children with severe sepsis in the United Kingdom: the results of the Paediatric Intensive Care Society sepsis audit. Archives of disease in childhood. 2009;94(5):348-53.
- Abstract Viewed: 308 times
- PDF Downloaded: 151 times
- HTML Downloaded: 39 times