A Case of Acute Leukemia Following Remission of COVID-19 Infection; an Urge to Search for a Probable Association
Archives of Academic Emergency Medicine,
Vol. 9 No. 1 (2021),
1 January 2021
,
Page e51
https://doi.org/10.22037/aaem.v9i1.1338
Abstract
Abstract:
Many aspects of Covid-19 infection, especially its complications and long-term health consequences are still unknown. Several reports concerning concomitant covid-19 infection and hematological disorders have been published recently. We aim to present a unique case of acute myeloid leukemia in a 61-year-old man with a previous history of covid-19 infection 40 days ago, with near complete resolution of signs and symptoms attributable to covid-19 infection. After 3 weeks, the patient presented again with progressive weakness, nausea, vomiting, and epigastric pain. No evidence of active covid-19 infection was observed. Instead, remarkable drop of hemoglobin and platelets relative to the values recorded in the discharge notes of the patient was observed. Further workup of the patient revealed evidence of acute leukemia and severe bone marrow involvement. We decided to present the current case as a concerning probable association.
- Case Report
- COVID-19
- Probable Association
How to Cite
References
2. He W, Chen L, Chen L, Yuan G, Fang Y, Chen W, et al. COVID-19 in persons with haematological cancers. Leukemia. 2020 2020/06/01;34(6):1637-45.
3. Frater JL, Zini G, d'Onofrio G, Rogers HJ. COVID-19 and the clinical hematology laboratory. International journal of laboratory hematology. 2020 Jun;42 Suppl 1:11-8. PubMed PMID: 32311826. Pubmed Central PMCID: PMC7264622. Epub 2020/04/21. eng.
4. Li Q, Cao Y, Chen L, Wu D, Yu J, Wang H, et al. Hematological features of persons with COVID-19. Leukemia. 2020 Aug;34(8):2163-72. PubMed PMID: 32528042. Pubmed Central PMCID: PMC7289481. Epub 2020/06/13. eng.
5. Zhang Y, Zeng X, Jiao Y, Li Z, Liu Q, Ye J, et al. Mechanisms involved in the development of thrombocytopenia in patients with COVID-19. Thrombosis research. 2020 Sep;193:110-5. PubMed PMID: 32535232. Pubmed Central PMCID: PMC7274097. Epub 2020/06/15. eng.
6. Spencer HC, Wurzburger R. COVID-19 presenting as neutropenic fever. Annals of hematology. 2020 Aug;99(8):1939-40. PubMed PMID: 32535707. Pubmed Central PMCID: PMC7292938. Epub 2020/06/15. eng.
7. Weinberg SE, Behdad A, Ji P. Atypical lymphocytes in peripheral blood of patients with COVID-19. British journal of haematology. 2020 Jul;190(1):36-9. PubMed PMID: 32420613. Pubmed Central PMCID: PMC7276903. Epub 2020/05/19. eng.
8. Aladily TN, Alnahhal J, Alshorman A, Awidi A. Transient increase in blast count following COVID-19 infection mimicking acute leukemia. International journal of laboratory hematology. 2020 Dec 12. PubMed PMID: 33314746. Epub 2020/12/15. eng.
9. Ali E, Badawi M, Abdelmahmuod E, Kohla S, Yassin MA. Chronic Lymphocytic Leukemia Concomitant with COVID 19: A Case Report. The American journal of case reports. 2020 Oct 24;21:e926062. PubMed PMID: 33098641. Pubmed Central PMCID: PMC7592339. Epub 2020/10/25. eng.
10. Khan AM, Ajmal Z, Raval M, Tobin E. Concurrent Diagnosis of Acute Myeloid Leukemia and COVID-19: A Management Challenge. Cureus. 2020 Aug 9;12(8):e9629. PubMed PMID: 32923230. Pubmed Central PMCID: PMC7478935. Epub 2020/09/15. eng.
11. Zhou X, Wang G, Chen L, Meng F, Huang L, Huang L, et al. Clinical characteristics of hematological patients concomitant with COVID-19. Cancer science. 2020 Sep;111(9):3379-85. PubMed PMID: 32619034. Pubmed Central PMCID: PMC7361643. Epub 2020/07/04. eng.
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