SBMU Journals
  • New Submission
  • Register
  • Login
  • English
    • 简体中文

Archives of Academic Emergency Medicine

  • Home
  • About
    • Policies
    • Editorial Team
    • Reviewer guideline
    • Statistics
    • Contact
  • Issues
    • Current
    • Archives
  • Announcements
  • Indexing/Abstracting
  • For authors
    • New Submission
    • Author guidelines
    • Article withdrawal
    • Peer review process
    • FAQ
  • Ethics
    • Ethical requirements
    • Plagiarism Policy
    • Authorship conflicts
    • Malpractice statements
    • Copyright Notice
    • Intellectual properties
    • Privacy Statement
    • Artificial intelligence & Authorship
    • Retraction Cosiderations
Advanced Search
  1. Home
  2. Archives
  3. Vol. 9 No. 1 (2021): Continuous volume
  4. Original/Research Article

Vol. 9 No. 1 (2021)

January 2021

Factors Affecting Pre-Hospital and In-Hospital Delays in Treatment of Ischemic Stroke; a Prospective Cohort Study

  • Neda Ghadimi
  • Nasrin Hanifi
  • Mohammadreza Dinmohammadi

Archives of Academic Emergency Medicine, Vol. 9 No. 1 (2021), 1 January 2021 , Page e52
https://doi.org/10.22037/aaem.v9i1.1267 Published: 2021-07-24

  • View Article
  • Download
  • Cite
  • References
  • Statastics
  • Share

Abstract

Introducion: The outcomes of acute ischemic stroke (AIS) are highly affected by time-to-treatment. The present study aimed to determine the factors affecting in-hospital and pre-hospital delays in treatmentof AIS.

Methods: This prospective study was carried out on 204 AIS patients referring to the stroke care unit in Zanjan (Iran) in 2019. The required data were collected by interviewing the patients and families and using patients’ records and observations.

Results: The maximum delay was related to onset-to-arrival time (288.19 ± 339.02 minutes). The logistic regression analysis indicated a statistically significant decline in the treatment delay via consultation after the initiation of symptoms (p< 0.001), transferring the patient through emergency medical service to the hospital (p<0.001), and patients’ perception regarding AIS symptoms (P< 0.001).

Conclusion: It is essential to inform people regarding AIS symptoms and referring to AIS treatment units to reduce the treatment time.

Keywords:
  • Acute stroke
  • Delay
  • Time-to-treatment
  • Mortality
  • Complication
  • Ischemic stroke
  • Prospective studies
  • Iran
  • pdf

How to Cite

1.
Ghadimi N, Hanifi N, Dinmohammadi M. Factors Affecting Pre-Hospital and In-Hospital Delays in Treatment of Ischemic Stroke; a Prospective Cohort Study. Arch Acad Emerg Med [Internet]. 2021 Jul. 24 [cited 2025 May 13];9(1):e52. Available from: https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/1267
  • ACM
  • ACS
  • APA
  • ABNT
  • Chicago
  • Harvard
  • IEEE
  • MLA
  • Turabian
  • Vancouver
  • Endnote/Zotero/Mendeley (RIS)
  • BibTeX

References

Ropper AH. Adams and Victor's principles of neurology: McGraw-Hill Medical Pub. Division New York; 2005.

Bernaitis N, Anoopkumar-Dukie S, Bills S, Crilly J. Evaluation of adult stroke presentations at an Emergency Department in Queensland Australia. International emergency nursing. 2019;44:25-9.

Kuhrij LS, Marang-van de Mheen PJ, van den Berg-Vos RM, de Leeuw F-E, Nederkoorn PJ. Determinants of extended door-to-needle time in acute ischemic stroke and its influence on in-hospital mortality: results of a nationwide Dutch clinical audit. BMC neurology. 2019;19(1):1-8.

Cohen JE, Itshayek E, Moskovici S, Gomori JM, Fraifeld S, Eichel R, et al. State-of-the-art reperfusion strategies for acute ischemic stroke. Journal of clinical neuroscience. 2011;18(3):319-23.

Scherf S, Limburg M, Wimmers R, Middelkoop I, Lingsma H. Increase in national intravenous thrombolysis rates for ischaemic stroke between 2005 and 2012: is bigger better? Bmc Neurology. 2016;16(1):1-6.

Bradley WG. Neurology in clinical practice: principles of diagnosis and management: Taylor & Francis; 2004.

Powers WJ, Rabinstein AA, Ackerson T, Adeoye OM, Bambakidis NC, Becker K, et al. 2018 guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2018;49(3):e46-e99.

Ebinger M, Kunz A, Wendt M, Rozanski M, Winter B, Waldschmidt C, et al. Effects of golden hour thrombolysis: a Prehospital Acute Neurological Treatment and Optimization of Medical Care in Stroke (PHANTOM-S) substudy. JAMA neurology. 2015;72(1):25-30.

Evenson KR, Foraker R, Morris DL, Rosamond WD. A comprehensive review of prehospital and in-hospital delay times in acute stroke care. International Journal of Stroke. 2009;4(3):187-99.

Metts EL, Bailey AM, Weant KA, Justice SB. Identification of rate-limiting steps in the provision of thrombolytics for acute ischemic stroke. Journal of pharmacy practice. 2017;30(6):606-11.

Ghiasian M, Mazaheri Sh, F HR. Factors Delaying Hospital Arrival Aftr Acute Stroke Onset. Avicenna J Clin Med. 2017;23(4):293-9.

Koksal EK, Gazioglu S, Boz C, Can G, Alioglu Z. Factors associated with early hospital arrival in acute ischemic stroke patients. Neurological Sciences. 2014;35(10):1567-72.

Ayromlou H, Soleimanpour H, Farhoudi M, Taheraghdam A, Hokmabadi ES, Ghafouri RR, et al. Eligibility assessment for intravenous thrombolytic therapy in acute ischemic stroke patients; evaluating barriers for implementation. Iranian Red Crescent Medical Journal. 2014;16(5):e11284.

Hassankhani H, Soheili A, Vahdati SS, Mozaffari FA, Fraser JF, Gilani N. Treatment Delays for Patients With Acute Ischemic Stroke in an Iranian Emergency Department: A Retrospective Chart Review. Annals of emergency medicine. 2019;73(2):118-29.

Dhaliwal J, Ferrigno B, Abiola O, Moskalik A, Sposito J, Wolansky LJ, et al. Hospital-based intervention to reduce tPA administration time. Interdisciplinary Neurosurgery. 2019;15:15-8.

Hsiao C-L, Su Y-C, Yang F-Y, Liu C-Y, Chiang H-L, Chen G-C, et al. Impact of code stroke on thrombolytic therapy in patients with acute ischemic stroke at a secondary referral hospital in Taiwan. Journal of the Chinese Medical Association. 2018;81(11):942-8.

Jin H, Zhu S, Wei JW, Wang J, Liu M, Wu Y, et al. Factors associated with prehospital delays in the presentation of acute stroke in urban China. Stroke. 2012;43(2):362-70.

Boehme AK, Esenwa C, Elkind MS. Stroke risk factors, genetics, and prevention. Circulation research. 2017;120(3):472-95.

Faiz KW, Sundseth A, Thommessen B, Rønning OM. Prehospital delay in acute stroke and TIA. Emerg Med J. 2013;30(8):669-74.

Al Khathaami AM, Mohammad YO, Alibrahim FS, Jradi HA. Factors associated with late arrival of acute stroke patients to emergency department in Saudi Arabia. SAGE open medicine. 2018;6:205.

Kasner SE, Chalela JA, Luciano JM, Cucchiara BL, Raps EC, McGarvey ML, et al. Reliability and validity of estimating the NIH stroke scale score from medical records. Stroke. 1999;30(8):1534-7.

Griesser A, Wagner G, Njamnshi A, Temperli P, Niquille M. Factors influencing emergency delays in acute stroke management. Swiss medical weekly. 2009;139(2728).

Ruiz RG, Fernández JS, Ruiz RMG, Bermejo MR, Arias ÁA, del Saz Saucedo P, et al. Response to symptoms and prehospital delay in stroke patients. Is it time to reconsider stroke awareness campaigns? Journal of Stroke and Cerebrovascular Diseases. 2018;27(3):625-32.

Springer MV, Labovitz DL. The Effect of Being Found with Stroke Symptoms on Predictors of Hospital Arrival. Journal of Stroke and Cerebrovascular Diseases. 2018;27(5):1363-7.

Sobral S, Taveira I, Seixas R, Vicente AC, Duarte J, Goes AT, et al. Late Hospital Arrival for Thrombolysis after Stroke in Southern Portugal: Who Is at Risk? Journal of Stroke and Cerebrovascular Diseases. 2019;28(4):900-5.

Bahnasy WS, Ragab OAA, Elhassanien ME. Stroke onset to needle delay: Where these golden hours are lost? An Egyptian center experience. eNeurologicalSci. 2019;14:68-71.

Sharma M, Helzner E, Sinert R, Levine SR, Brandler ES. Patient characteristics affecting stroke identification by emergency medical service providers in Brooklyn, New York. Internal and emergency medicine. 2016;11(2):229-36.

Mowla A, Doyle J, Lail NS, Rajabzadeh-Oghaz H, Deline C, Shirani P, et al. Delays in door-to-needle time for acute ischemic stroke in the emergency department: a comprehensive stroke center experience. Journal of the neurological sciences. 2017;376:102-5.

  • Abstract Viewed: 1400 times
  • pdf Downloaded: 571 times

Download Statastics

  • Linkedin
  • Twitter
  • Facebook
  • Google Plus
  • Telegram

Make a Submission

Make a Submission

SJR

SCImago Journal & Country Rank

Current Issue

  • Atom logo
  • RSS2 logo
  • RSS1 logo

Information

  • For Readers
  • For Authors
  • For Librarians
  • Home
  • Archives
  • Submissions
  • About the Journal
  • Editorial Team
  • Contact

This journal is distributed under the terms of CC BY-NC 3.0. Design and publishing by SBMU journals. All credits and honors to PKP for their OJS. 

 Sitemap | ISSN-ONLINE: 2645-4904

Support Contact: ma.saghaei63@gmail.com

With the goal of net zero carbon emissions, this journal is published only in electronic format.

Powered by OJSPlus