The Effect of Photodynamic Therapy in the Treatment of Chronic Periodontitis: A Review of Literature

Mansour Meimandi--- Periodontist, Associate Professor, Periodontics Dept., School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran,
Mohammad Reza Talebi Ardakani--- Periodontist, Associate Professor, Periodontics Dept., School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran,
Azade Esmaeilnejad--- Periodontist, Associate Professor, Periodontics Dept., School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran,
Parisa Yousefnejad--- Periodontist, Associate Professor, Periodontics Dept., School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran,
Khosro Saebi--- Private Practice, Tehran, Iran,
Mohammad Hossein Tayeed--- Dental Student, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Abstract


21

Introduction: Chronic periodontitis is the most common periodontal disease which is related to the chronic accumulation of bacterial plaque. Since mechanical methods are not sufficient in the treatment of this disease, administration of local/systemic antibiotic is recommended following mechanical debridement. However, side effects of antibiotics such as microbial resistance and patient allergy led to development of alternative methods. One of these suggested methods is the antimicrobial photodynamic therapy (aPDT). PDT is a local noninvasive treatment modality without the side effects caused by antibiotics. The aim of this study was to review the articles related to the application of PDT with laser in the treatment of chronic periodontitis.

Review of literature: In the present review of literature, the authors used key words such as Chronic Periodontitis, Laser and Photodynamic therapy, and conducted a literature search via Google Scholar and PubMed for the period of 1990 to 2015. A total of 47 articles in English were found. The articles that were not associated with the topic of research and review articles were deleted and only clinical trials were evaluated. After reviewing 23 articles’ abstracts, the full texts of 16 articles were analyzed.

Conclusion: Considering the safety, the lack of side effects and general advantages like more patient compliance, the PDT treatment with SRP is recommended as an efficient adjunctive modality for the treatment of localized chronic periodontitis especially during the maintenance phase in non-surgical treatment.

Keywords


Chronic periodontitis; Laser; Photodynamic therapy

Full Text:

XML

5

PDF

30

References


Bassir SH, Moslemi N, Jamali R ,Mashmouly S. Fekrazad R, Chiniforush N, et al. Photoactivated disinfection using light-emitting diodes as an adjunct in the management of chronic periodontitis: a pilot double-blind split- mouth randomized clinical trial. J Clin Periodontol. 2013; 40: 65-72.

Tanner AC. Anaerobic culture to detect periodontal and caries pathogens. J Oral Biosci. 2015; 57: 18-26.

Cobb C M . Non-surgical pocket therapy: mechanical. Anne Of Periodontology. 1996; 1: 443-490.

Slots J, Rams TE. Antibiotics in periodontal therapy: advantages and disadvantages. J Clin periodontol. 1990; 17: 479-93.

Gillies M, Ranakusuma A, Hoffmann T, Thorning S, Mc Guire T, Glasziou P, et al .Common harms from amoxicillin: a systematic review and meta-analysis of randomized placebo-controlled trials for any indication. CMAJ. 2015 ; 6: 187: E21-31.

Petersilka GJ, Tunkel J, Barakos K, Heinecke A, Häberlein I, Flemmig TF. Subgingival plaque removal at interdental sites using a low-abrasive air polishing powder. J Periodontol. 2003; 74: 307-11.

Parker S. The use of diffuse laser photonic energy and indocyanine green photosensitizer az an adjunct to periodontal thrrapy. Br Dent J. 2013; 215: 167-71.

Garg AD, Maes H ,Romano E, Agostinis P. Autophagy a major adaptation pathway shaping cancer cell death and anti ancer immunity responses following photodynamic therapy. Photochem Photobiol Sci. 2015; 14: 1410-24 .

Allison RR, Baganto VS ,Cuenca R, Dowinie GH, Sibata CH. The future of photodynamic therapy in oncology .Future Oncol. 2006; 2: 53-71.

Raghavendra M, Koregol A, Bhola S. Photodynamic therapy : a targeted therapy in eriodontics. Aust Dent J. 2009; 54: S102-9.

Ochsner M. Photophysical and photobiological processes in the photodynamic therapy of tumours. J Photochem Photobiol B. 1997; 39: 1-18.

Moan J, Berg K. The photodegradation of por hyrins in cell that can be used to estimate the lifetime of singlet oxygen . Photochem Photobiol. 1991 ;53: 549-53.

Andersen R ,Loebel N Hammond D, Wilson M. Treatment of periodontal disease by photodisinfection compared to scaling and root planing. J Clin Dent. 2007; 18: 34-8.

Braun A, Dehn C, Krause F, Jepsen S. Short –term clinical effects of adjuctive antimicrobial photodynamic therapy in periodontal treatment: a randomized clinical trial. J Clin Periodontol. 2008; 35: 877-84.

Christodoulides N, Nikoldakis D, Chondros P, Becker J, Schwarz F, Rossler R,et al. Photodynamic therapy as an adjunct to non- surgical periodontal treatment a randomized controlled clinical trial. J Periodontol. 2008 ;79: 1638-44.

Chondros P, Nikolidakis D, Christodoulides N, Rossler R , Gutknecht N, Sculean A. A Photodynamic therapy as adjunct to non – surgical periodontal treatment in patients on periodontal maintenance: a randomized, controlled clinical trial. Laser Med Sci. 2009; 24: 681-8.

Polansky R, Haas M, Heschl A ,Wimmer G. Clinical effectiveness of photodynamic therapy in treatment of periodontitis. J Clin Periodontol. 2009; 36: 575-80.

Ruhling A, Fanghanel J, Hushmand M, Kuhr A , Meisel P , Schwahn C, et al. Photodynamic therapy of persistent pockets in maintenance patients-a clinical study .Clin Oral Investig. 2010; 14: 637-44.

Lui J ,Corbet EF ,Jin L. Combined photodynamic and low -level laser therapies as an adjunct to non-surgical treatment of chronic periodontitis. J Periodontol Res. 2011; 46: 89-96.

Aykol G, Baser U, Maden I, Kazak Z, Onan U, Tanrikulu Kucuk S, et al. The effect of low- level laser therapy as an adjunct to non-surgical periodontal treatment . J Periodontol. 2011 ; 82: 481-8.

Cappuyns I, Cionea N, Wick P, Giannopoulou C, Mombelli A.Treatment of residual pockets with photodynamic therapy , diode laser, or deep scaling . A randomized split- mouth controlled clinical trial . Lasers Med Sci. 2011 (Epub ahead of print).

Noro Filho GA, Casarin RC, Casti MZ , Giovani EM. PDT in non- surgical treatment of periodontitis in HIV patients: a split –mouth , randomized clinical trial . Lasers Surge Med. 2012; 44 : 296-302.

Berakdar M, Callaway A, Fakhrddin M, Rob A, Willershausen B. Comparison between scaling –root planning and SRP/Photodynamic therapy: six –month study . Head Face Med. 2012 ; 8:12.

Giannelli M, Formigli L, Lorenzini L, Bani D. Combined photoablative and photodynamic diode laser therapy as an adjunct to non-surgical periodontal treatment: a randomized Split-mouth clinical trial. J Clin Periodontol. 2012; 39: 962-70.

Balata ML, Andrade IP, Santos DB, Cavalcanti AN, Tunes Uda R, Ribeiro Edel P, et al. Photodynamic therapy associated with full- mouth ultrasonic debridement in the treatment of severe chronic periodontitis: a randomized –controlled clinical trial. J Appl Oral Sci. 2013; 21: 208-14.

Souza sl, Andrade PF, Silva JS, Tristao FS, Rochea FA, Palioto DB, et al. Effect of antimicrobial photodynamic therapy on transforming growth factor- B1 levels in the gingival crevicular fluid. Photomed Laser Surg. 2013; 31: 65-71.

Pourabbas R, Kashefimehr A, Rahmanpour N, Babaloo Z, Kishen A, Howard C, et al. A Effects of photodynamic therapy on clinical and gingival crevicular fluid inflammatory biomarkers in chronic periodntitis: A split-mouth randomized clinical trial. J Periodontol. 2014; 85: 1222-9.

Kolbe MF, Fernanda V, Ribeir O, Luchesi VH, Casarin RC, Sallum EA, et al. Photodynamic therapy during supportive periodontal care : Clinical microbiologic immunoinflammatory, and patient-centered performance in a Split-mouth randomized clinical trial . J Periodontol. 2014 ; 8: 277-86.

Chan Y, Lai CH. Bacteriocidal effects of different laser wavelengths on periodontopathic germs in photodynamic therapy. Lasers Med Sci. 2003; 18: 51-5.

de Paula Eduardo C, de Freitas PM, Esteves- O liveria M, Aranha AC, Ramalho KM, Simoes A, et al. Laser phototherapy in the treatment of periodontal disease. Lasers Med Sci. 2010 ; 25: 781-92.

Malik R, Manocha A, Suresh DK. Photodynamic therapy .Astrategic review . Indian J Dent Res. 2010 ; 21: 285-91.

Takasaki AA, Aoki A, Mizutani K, Schwarz F, Sculean A, Wang CY, et al. Application of antimicrobial photodynamic therapy in periodontal and peri – implant diseases . Periodontol. 2000 .2009; 51: 109-40.




Copyright © 2012 J Lasers Med Sci "Powered by Open Journal Systems"

 

Site Map | Privacy Statement | About JLMS | Contact | Search| Current | Archives | Open Access

ISSN: 2008-9783/E.ISSN: 2228-6721. Published quarterly by: Laser Application in Medical Sciences Research Center