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Vol. 2 No. 1 (2015)

March 2015

A case of Guillain-Barre syndrome presented with bilateral pseudo-internuclear ophthalmoplegia

  • Sadegh Izadi
  • Iman Sabzgolin

International Clinical Neuroscience Journal, Vol. 2 No. 1 (2015), 3 March 2015 , Page 33-35
https://doi.org/10.22037/icnj.v2i1.8198 Published: 2015-02-26

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Abstract

Guillain-Barre syndrome (GBS) or acute idiopathic polyradiculoneuritis is an acquired immune-mediated inflammatory and mainly demyelinating disorder of the peripheral nervous system. Cranial nerves are affected in over 50% of all cases, with the facial nerves being affected the most. It uncommonly presents as atypical forms such as brachial pharyngeal variant, miller fisher and other restricted forms. Herein, we reported a 44 year old male with GBS who presented with diplopia and bilateral pseudo- internuclear ophthalmoplegia. Initially, the patient was confused as a case of multiple sclerosis but finally diagnosis of GBS was made. Although internuclear ophthalmoplegia is a typical feature of multiple sclerosis, it may be seen as a rare manifestation of GBS as well.

Keywords:
  • Guillain-Barre Syndrome
  • Internuclear Ophthalmoplegia
  • Multiple Sclerosis
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How to Cite

1.
Izadi S, Sabzgolin I. A case of Guillain-Barre syndrome presented with bilateral pseudo-internuclear ophthalmoplegia. Int Clin Neurosci J [Internet]. 2015 Feb. 26 [cited 2026 Jul. 25];2(1):33-5. Available from: https://journals.sbmu.ac.ir/neuroscience/article/view/8198
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References

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Burina A, Sinanović O, Smajlović D, Vidović M. Bilateral oculomotor nerve palsy in Guillain-Barre syndrome. Med Arh. 2008; 62(2):119-20.

Lo YL. Clinical and immunological spectrum of the Miller Fisher syndrome. Muscle Nerve. 2007; 36(5):615-27.

Obuchowska I, Mariak Z. Internuclear ophthalmoplegia,causes, symptoms and management. Klinika Oczna. 2009; 111(4-6):165-7.

Fisher M. An unusual variant of acute idiopathic polyneuritis (syndrome of ophthalmoplegia, ataxia and areflexia). N Engl J Med. 1956; 255(2); 57–65.

Walsh WP, Hafner JF, Kattah JC. Bilateral internuclear ophthalmoplegia following minor head trauma. J Emerg Med. 2003 Jan;24(1):19-22.

Kim JS. Internuclear ophthalmoplegia as an isolated or predominant symptom of brainstem infarction. Neurology. 2004 May 11;62(9):1491-6.

Diamond S, Schear HE, Leeds MF. Pseudo-internuclear oculomotor ophthalmoplegia secondary to Guillain-Barre polyneuritis simulating myasthenia gravis in a air transport pilot. Aviat Space Environ Med. 1975; 46(2):204-7.

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