International Clinical Neuroscience Journal

Vol. 8 No. 2 (2021)

Prevalence of Depression and Anxiety and Related Factors in Patients With Parkinson’s Disease Depression and Anxiety in Parkinson's Disease

International Clinical Neuroscience Journal, Vol. 8 No. 2 (2021), 27 March 2021 , Page 85-89

Abstract

Background: Parkinson’s disease is a chronic and progressive disease in which patients show symptoms of psychiatric diseases such as anxiety and depression leading to decreased quality of life. So far, few studies have been done in this field in Iran.
Methods: The study is a cross-sectional study that investigates the prevalence of anxiety and depression and their related factors in patients with Parkinson’s disease. In this study, 74 patients with Parkinson’s disease and 74 healthy individuals were evaluated and using by Beck’s Depression and Anxiety Inventories.
Results: The prevalence of depression and anxiety in patients with Parkinson’s was 37.83% and 78.38%, respectively. The mean score of depression and anxiety was significantly higher in the patient group (P<0.001). Older age, female sex, a higher level of education and a longer duration of illness were significantly associated with more depression and anxiety (P<0.05). Multiple regression models showed that age was a predictive factor in depression. With respect to anxiety, age and duration of the disease were predictive factors.
Conclusion: The severity of depression and anxiety were significantly higher in patients with Parkinson’s disease compared to healthy individuals. Age and duration of the disease play a significant role in predicting the severity of depression and anxiety in such patients.

Keywords:
  • Parkinson’s disease
  • Depression
  • Anxiety
  • Prevalence
  • Beck Depression Inventory-II
  • Beck’s Anxiety Inventory

How to Cite

1.
Pir hayati M, Eydivandi N, Khodashenas M, Fallah H. Prevalence of Depression and Anxiety and Related Factors in Patients With Parkinson’s Disease: Depression and Anxiety in Parkinson’s Disease. Int Clin Neurosci J [Internet]. 2021 Mar. 28 [cited 2026 Jul. 5];8(2):85-9. Available from: https://journals.sbmu.ac.ir/neuroscience/article/view/33799

References

Baghoori D, Rezaei M, Mirzakhani N, Irani A, Akbarzadeh Baghban A. Face and content validity of Persian version of Parkinson Fatigue Scale (PFS-16) in people with Parkinson’s disease. Scientific Journal of Rehabilitation Medicine. 2016;5(1):85-92.

Carod-Artal FJ, Ziomkowski S, Mourão Mesquita H, Martínez- Martin P. Anxiety and depression: main determinants of health-related quality of life in Brazilian patients with Parkinson’s disease. Parkinsonism Relat Disord. 2008;14(2):102-8. doi: 10.1016/j.parkreldis.2007.06.011.

Soleimani MA, Bastani F, Negarandeh R, Greysen R. Perceptions of people living with Parkinson’s disease: a qualitative study in Iran. Br J Community Nurs. 2016;21(4):188- 95. doi: 10.12968/bjcn.2016.21.4.188.

Roohani M, Shahidi G, Miri S. Demographic study of Parkinson’s disease in Iran: data on 1656 cases. Iran J Neurol. 2011;10(1-2):19-21.

Wee N, Kandiah N, Acharyya S, Chander RJ, Ng A, Au WL, et al. Depression and anxiety are co-morbid but dissociable in mild Parkinson’s disease: a prospective longitudinal study of patterns and predictors. Parkinsonism Relat Disord. 2016;23:50-6. doi: 10.1016/j.parkreldis.2015.12.001.

Schrag A, Taddei RN. Depression and anxiety in Parkinson’s disease. In: Chaudhuri KR, Titova N, eds. International Review of Neurobiology. Vol 133. Academic Press; 2017. p. 623-55.

Sarokhani D, Parvareh M, Hasanpour Dehkordi A, Sayehmiri K, Moghimbeigi A. Prevalence of depression among Iranian elderly: systematic review and meta-analysis. Iran J Psychiatry. 2018;13(1):55-64.

Pachana NA, Egan SJ, Laidlaw K, Dissanayaka N, Byrne GJ, Brockman S, et al. Clinical issues in the treatment of anxiety and depression in older adults with Parkinson’s disease. Mov Disord. 2013;28(14):1930-4. doi: 10.1002/mds.25689.

Bahrami P, Zibaee M, Zebardast H, Ebrahimzadeh F, Yadegari S, Rezaee M. Evaluation of disabilities of Parkinson’s disease patients in neurology ward of Shohaday-e-Ashayer hospital and private neurology clinics in 2010. Yafteh. 2012;14(3):25- 35. [Persian].

Shakeri J, Chaghazardi M, Abdoli N, Arman F, Hoseini SD, Shakeri H. Disease-related variables and depression among Iranian patients with Parkinson’s disease. Iran Red Crescent Med J. 2015;17(10):e30246. doi: 10.5812/ircmj.30246.

Rajabi G, Karju Kasmai S. Psychometric properties of a Persian language version of the Beck Depression Inventory second edition. Educational Measurement. 2013;3(10):139- 158. [Persian].

García-Batista ZE, Guerra-Peña K, Cano-Vindel A, Herrera- Martínez SX, Medrano LA. Validity and reliability of the Beck Depression Inventory (BDI-II) in general and hospital population of Dominican Republic. PLoS One. 2018;13(6):e0199750. doi: 10.1371/journal.pone.0199750.

Visser M, Leentjens AF, Marinus J, Stiggelbout AM, van Hilten JJ. Reliability and validity of the Beck Depression Inventory in patients with Parkinson’s disease. Mov Disord. 2006;21(5):668-72. doi: 10.1002/mds.20792.

Huang SL, Hsieh CL, Wu RM, Lu WS. Test-retest reliability and minimal detectable change of the Beck Depression Inventory and the Taiwan Geriatric Depression Scale in patients with Parkinson’s disease. PLoS One. 2017;12(9):e0184823. doi: 10.1371/journal.pone.0184823.

Fydrich T, Dowdall D, Chambless DL. Reliability and validity of the Beck Anxiety Inventory. J Anxiety Disord. 1992;6(1):55- 61. doi: 10.1016/0887-6185(92)90026-4.

Kaviani H, Mousavi AS. Psychometric properties of the Persian version of Beck Anxiety Inventory (BAI). Tehran Univ Med J. 2008;66(2):136-40. [Persian].

Zhu K, van Hilten JJ, Marinus J. Onset and evolution of anxiety in Parkinson’s disease. Eur J Neurol. 2017;24(2):404-11. doi: 10.1111/ene.13217.

Cui SS, Du JJ, Fu R, Lin YQ, Huang P, He YC, et al. Prevalence and risk factors for depression and anxiety in Chinese patients with Parkinson’s disease. BMC Geriatr. 2017;17(1):270. doi: 10.1186/s12877-017-0666-2.

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