Simulation and Study of Temperature Distribution in Living Biological Tissues under Laser Irradiation
Journal of Lasers in Medical Sciences,
Vol. 5 No. 3 (2014),
22 June 2014
,
Page 135-139
Abstract
Introduction: With the rapid increase in use of lasers in medical treatments, it is important to understand the mechanisms of heat transfer in biological tissues in order to minimize damage to the tissues resulting from extra heat applied. The aim of this study is to investigate the temperature distribution in living biological tissues when laser irradiation is used in a treatment.
Methods: In this work a model was suggested to study the impact of several parameters such as (laser power, exposure time, laser spot size) on the temperature distribution within skin tissues when subjected to a laser source. A three-dimensional finite element thermal model of biological tissues was developed using bio-heat equation to describe heat transfer in living tissues.
Results: Temperature distribution within skin tissues subjected to laser heating is calculated in details using the Finite element method and a suggested model; the results are presented in figures and tables showing the effects of Laser spot size, power and exposure time on temperature distribution within treated tissue.
Conclusion: the results presented in this work are expected to be useful in optimizing Laser spot size, power and exposure time for a variety of laser applications medicine and surgery.
- temperature
- laser
- simulation
- finite element method.
How to Cite
References
Dua R, Chakraborty S, A novel modeling and simulation technique of photo-thermal interactions between lasers and living biological tissues undergoing multiple changes in phase. Comput Biol Med 2004;35(5):447-62.
R. Rox Anderson, M.D., Coetaneous Laser Surgery, Second edition.
Necati Ozisk N, Heat Conduction Department Of Mechanical And Aerospace Engineering, North Carolina State University Raleigh, Copyright 1980 by John wiley @ sous Inc.
Chua KJ, Ho JC, Chou SK, Islam MR. On The Study Of The Temperature Distribution Within a human eye Subjected To a Laser Source. Int Com Heat Mass Transfer 2005; 32 (5):666-76.
FEMLAB 3.2, Available at: http://www.comsol.com/products/femlab
Wang XJ, Zeng CC, Liu SH. The effects tissue temperature distribution low intensity laser irradiation. Proc SPIE 2005; 5630:780.
Niemz M. Laser-Tissue Interactions, Fundamental and Applications.1, Springer-Verlag Berlin Heidelberg 1996.
Muller G, Roggan A, Laser Induced Interstitial Thermotherapy, Copyright 1995 The society of Photo-Optical Instrumentation Engineering.
Sobol EN, Makroppoulou M, Serafetinides AA, Yova D. Theoretical model CO2 laser ablation soft tissue phantoms,.II Nuovo Cimento D 1996;18: 483-90.
Baranov GA, Belyaev AA, Onikienko SB, Smirnov SA, Khukharev VV. Modification Of Biological Objects In Water Media By CO2 Laser Radiation. J Quantum Electron 2005; 35:876-72.
Mohammed Y, Verhey JF. A finite element method model to simulate laser interstitial thermo therapy in anatomical inhomogeneous regions. Biomed Eng Online 2005;4:2.
Pustovalov VK, Jean B. Theoretical Investigations of the Process Of Selective Laser Interaction With melanin Granules In Pigmented Tissues For Laser Applications In medicine. Laser Physics 2006;16:1011-28.
He Y1, Shirazaki M, Liu H, Himeno R, Sun Z. A numerical coupling model to analyze the blood flow in human breast tumor under laser irradiation. Comput Biol Med 2006;36(12):1336-50.
Rossi F, Pini R, Menabuoni L. 3D Simulation and Experimental Comparison of Temperature Dynamics in Laser Welding Cornea. J Biomed Opt 2007;12(1):014031.
Ng EY, Ooi EH. FEM simulation of the eye structure with bioheat analysis. Comput Methods Programs Biomed 2006 ;82(3):268-76.
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