Notable Enhancement of Facial Scarring Following Autologous Melanocyte-Keratinocyte Transplantation and NUVB Therapy: A Case Report Autologous Melanocyte-Keratinocyte Transplantation and NUVB Therapy in Scar
Journal of Lasers in Medical Sciences,
Vol. 13 (2022),
10 January 2022
,
Page e78
Abstract
Introduction: There are various types of treatment targeting the healing of traumatic or accidental skin scars. Transplantation of skin grafts and surgical alternatives, including autologous transplantation of melanocyte-keratinocyte suspension, has also been suggested previously. This study is representing a case of previous skin graft transplantation, complaining of scar formation and discoloration on the transplanted segment.
Case Presentation: The patient was a 37-year-old lady. This patient underwent melanocytekeratinocyte suspension transplantation and narrow-band ultraviolet B (NUVB) therapy and could reach 40% re-pigmentation enhancement. This method could be introduced as an efficient and safe method of approaching facial scarring.
Conclusion: This method could be introduced as an efficient and safe method of approaching facial scarring.
- Cell therapy
- Melanocytes
- Skin graft
- Transplantation
- NUVB therapy
How to Cite
References
Newberry CI, Thomas JR, Cerrati EW. Facial Scar Improvement Procedures. Facial plastic surgery : FPS. 2018;34(5):448-57.
Nunes DH, Esser LM. Vitiligo epidemiological profile and the association with thyroid disease. Anais brasileiros de dermatologia. 2011;86(2):241-8.
Majid I, Imran S. Ultrathin split-thickness skin grafting followed by narrowband UVB therapy for stable vitiligo: an effective and cosmetically satisfying treatment option. Indian journal of dermatology, venereology and leprology. 2012;78(2):159-64.
Rusfianti M, Wirohadidjodjo YW. Dermatosurgical techniques for repigmentation of vitiligo. International journal of dermatology. 2006;45(4):411-7.
Mulekar SV. Long-term follow-up study of 142 patients with vitiligo vulgaris treated by autologous, non-cultured melanocyte-keratinocyte cell transplantation. International journal of dermatology. 2005;44(10):841-5.
Huggins RH, Henderson MD, Mulekar SV, Ozog DM, Kerr HA, Jabobsen G, et al. Melanocyte-keratinocyte transplantation procedure in the treatment of vitiligo: the experience of an academic medical center in the United States. Journal of the American Academy of Dermatology. 2012;66(5):785-93.
Olsson MJ, Juhlin L. Leucoderma treated by transplantation of a basal cell layer enriched suspension. The British journal of dermatology. 1998;138(4):644-8.
Paul M. Autologous Non-cultured Basal Cell-Enriched Epidermal Cell Suspension Transplantation in Vitiligo: Indian Experience. Journal of cutaneous and aesthetic surgery. 2011;4(1):23-8.
Neves DR, Régis Júnior JR, Oliveira PJ, Zac RI, Silveira Kde S. Melanocyte transplant in piebaldism: case report. Anais brasileiros de dermatologia. 2010;85(3):384-8.
Rao A, Gupta S, Dinda AK, Sharma A, Sharma VK, Kumar G, et al. Study of clinical, biochemical and immunological factors determining stability of disease in patients with generalized vitiligo undergoing melanocyte transplantation. The British journal of dermatology. 2012;166(6):1230-6.
Vincent AG, Kadakia S, Barker J, Mourad M, Saman M, Ducic Y. Management of Facial Scars. Facial plastic surgery : FPS. 2019;35(6):666-71.
Machado Filho CD, Almeida FA, Proto RS, Landman G. Vitiligo: analysis of grafting versus curettage alone, using melanocyte morphology and reverse transcriptase polymerase chain reaction for tyrosinase mRNA. Sao Paulo medical journal = Revista paulista de medicina. 2005;123(4):187-91.
- Abstract Viewed: 221 times
- PDF Downloaded: 176 times