Effect of Laser-Assisted Hair Removal (LAHR) on the Quality of Life and Depression in Hirsute Females: A Single-Arm Clinical Trial
Journal of Lasers in Medical Sciences,
Vol. 13 (2022),
10 January 2022
,
Page e46
Abstract
Introduction:
Hirsutism, mainly due to poly cystic ovary syndrome (PCOS), causes stress, anxiety and depression in females. LAHR is currently accepted as a good treatment option for hirsutism. The goal of the current study was to ascertain how LAHR affected the degree of hirsutism, quality of life, and depression in hirsute females.
Methods:
A single arm before/after clinical trial was designed and performed in the Razi Hospital Laser Clinic over a 15-months period. All hirsute females visiting Razi hospital laser clinic, were enrolled and received three sessions of LAHR every 4-6 weeks if they were interested and signed an informed consent. Before the commencement of LAHR and six to eight weeks after the last session, the Ferriman-Gallwey score (hirsutism severity), Beck score (depression index) and DLQI score (quality of life index) were calculated and stored.
Results:
There were 80 subjects in all. The mean± (SD) of the Ferriman-Gallwey score was reduced from 7.05 ± 2.27 to 4.91 ± 2.41, p<0.001. Beck depression score’s mean± (SD) was reduced from 13.3 ± 8.7 to 10.2 ± 8.4, p<0.001 and mean± (SD) of DLQI score was decreased from 5.6 ± 5.2 to 3.5 ± 2.3, p<0.001. No significant complication were reported.
Conclusion:
LAHR can improve hirsutism related depression and degradation of quality of life as well as hirsutism physical signs.
- hirsutism, quality of life, depression, laser assisted hair removal.
How to Cite
References
2. Rabinowitz S, Cohen R, Le Roith D. Anxiety and hirsutism. Psychol Rep. 1983;53(3 Pt 1):827-830. doi:10.2466/pr0.1983.53.3.827
3. Barth JH, Catalan J, Cherry CA, Day A. Psychological morbidity in women referred for treatment of hirsutism. J Psychosom Res. 1993;37(6):615-619. doi:10.1016/0022-3999(93)90056-l
4. Drosdzol A, Skrzypulec V, Plinta R. Quality of life, mental health and self-esteem in hirsute adolescent females. J Psychosom Obstet Gynaecol. 2010;31(3):168-175. doi:10.3109/0167482X.2010.501398
5. Lipton MG, Sherr L, Elford J, Rustin MHA, Clayton WJ. Women living with facial hair: the psychological and behavioral burden. J Psychosom Res. 2006;61(2):161-168. doi:10.1016/j.jpsychores.2006.01.016
6. Sonino N, Fava GA, Mani E, Belluardo P, Boscaro M. Quality of life of hirsute women. Postgrad Med J. 1993;69(809):186-189. doi:10.1136/pgmj.69.809.186
7. Azziz R. The evaluation and management of hirsutism. Obstet Gynecol. 2003;101(5 Pt 1):995-1007. doi:10.1016/s0029-7844(02)02725-4
8. Cronin L, Guyatt G, Griffith L. Development of a health-related quality-of-life questionnaire (PCOSQ) for women with polycystic ovary syndrome (PCOS). J Clin Endocrinol Metab. 1998;83(6):1976-1987. doi:10.1210/jcem.83.6.4990
9. Guyatt G, Weaver B, Cronin L, Dooley JA, Azziz R. Health-related quality of life in women with polycystic ovary syndrome, a self-administered questionnaire, was validated. J Clin Epidemiol. 2004;57(12):1279-1287. doi:10.1016/j.jclinepi.2003.10.018
10. Loo WJ, Lanigan SW. Laser treatment improves quality of life of hirsute females. Clin Exp Dermatol. 2002;27(6):439-441. doi:10.1046/j.1365-2230.2002.01071.x
11. Lee CM. Laser-assisted hair removal for facial hirsutism in women: A review of evidence. J Cosmet Laser Ther off Publ Eur Soc Laser Dermatol. 2018;20(3):140-144. doi:10.1080/14764172.2017.1376099
12. Alizadeh N, Ayyoubi S, Naghipour M. Can laser treatment improve quality of life of hirsute women? Int J Womens Health. 2017; 9:777-780. doi:10.2147/IJWH.S137910
13. Maziar A, Farsi N, Mandegarfard M. Unwanted facial hair removal with laser treatment improves quality of life of patients. J Cosmet Laser Ther Off Publ Eur Soc Laser Dermatol. 2010;12(1):7-9. doi:10.3109/14764170903449802
14. Richter P, Werner J, Heerlein A, Kraus A, Sauer H. On the validity of the Beck Depression Inventory. A review. Psychopathology. 1998;31(3):160-168. doi:10.1159/000066239
15. Ghassemzadeh H, Mojtabai R, Karamghadiri N, Ebrahimkhani N. Psychometric properties of a Persian-language version of the Beck Depression Inventory--Second edition: BDI-II-PERSIAN. Depress Anxiety. 2005;21(4):185-192. doi:10.1002/da.20070
16. Finlay AY. Quality of life indices. Indian J Dermatol Venereol Leprol. 2004;70(3):143-148.
17. Basra MKA, Fenech R, Gatt RM, Salek MS, Finlay AY. The Dermatology Life Quality Index 1994-2007: a comprehensive review of validation data and clinical results. Br J Dermatol. 2008;159(5):997-1035. doi:10.1111/j.1365-2133.2008.08832.x
18. Aghaei S, Sodaifi M, Jafari P, Mazharinia N, Finlay AY. DLQI scores in vitiligo: reliability and validity of the Persian version. BMC Dermatol. 2004;4:8. doi:10.1186/1471-5945-4-8
19. Ferriman D, Gallwey JD. Clinical assessment of body hair growth in women. J Clin Endocrinol Metab. 1961;21:1440-1447. doi:10.1210/jcem-21-11-1440
20. Ramezani Tehrani F, Minooee S, Azizi F. Validation of a simplified method to assess hirsutism in the Iranian population. Eur J Obstet Gynecol Reprod Biol. 2014;174:91-95. doi:10.1016/j.ejogrb.2013.12.008
21. Davoudi SM, Behnia F, Gorouhi F. Comparison of long-pulsed alexandrite and Nd:YAG lasers, individually and in combination, for leg hair reduction: an assessor-blinded, randomized trial with 18 months of follow-up. Arch Dermatol. 2008;144(10):1323-1327. doi:10.1001/archderm.144.10.1323
22. Haedersdal M, Wulf HC. Evidence-based review of hair removal using lasers and light sources. J Eur Acad Dermatol Venereol JEADV. 2006;20(1):9-20. doi:10.1111/j.1468-3083.2005.01327.x
23. Roche A, Sedgwick PM, Harland CC. Laser treatment for female facial hirsutism: are quality-of-life benefits sustainable? Clin Exp Dermatol. 2016;41(3):248-252. doi:10.1111/ced.12775
24. Clayton WJ, Lipton M, Elford J, Rustin M, Sherr L. A randomized controlled trial of laser treatment among hirsute women with polycystic ovary syndrome. Br J Dermatol. 2005;152(5):986-992. doi:10.1111/j.1365-2133.2005.06426.x
25. Meier RK. Polycystic Ovary Syndrome. Nurs Clin North Am. 2018;53(3):407-420. doi:10.1016/j.cnur.2018.04.008
26. Spritzer PM, Barone CR, Oliveira FB de. Hirsutism in Polycystic Ovary Syndrome: Pathophysiology and Management. Curr Pharm Des. 2016;22(36):5603-5613. doi:10.2174/1381612822666160720151243
27. Grymowicz M, Rudnicka E, Podfigurna A, et al. Hormonal Effects on Hair Follicles. Int J Mol Sci. 2020;21(15):E5342. doi:10.3390/ijms21155342
28. Kolhe JV, Chhipa AS, Butani S, Chavda V, Patel SS. PCOS and Depression: Common Links and Potential Targets. Reprod Sci Thousand Oaks Calif. Published online October 12, 2021. doi:10.1007/s43032-021-00765-2
29. Damone AL, Joham AE, Loxton D, Earnest A, Teede HJ, Moran LJ. Depression, anxiety and perceived stress in women with and without PCOS: a community-based study. Psychol Med. 2019;49(9):1510-1520. doi:10.1017/S0033291718002076
- Abstract Viewed: 364 times
- PDF Downloaded: 243 times