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  3. Vol. 11 No. 2 (2020): Spring
  4. Review Article

Vol. 11 No. 2 (2020)

March 2020

Is Holmium Laser Enucleation of Prostate a Good Surgical Alternative in Benign Prostatic Hyperplasia Management? A Review Article

  • Amirreza Abedi
  • Mohammad Reza Razzaghi
  • Amirhossein Rahavian
  • Ebrahim Hazrati
  • Fereshte Aliakbari
  • Vahid Vahedisoraki
  • Farzad Allameh

Journal of Lasers in Medical Sciences, Vol. 11 No. 2 (2020), 15 March 2020 , Page 197-203
Published: 2020-03-15

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Abstract

Several therapeutic approaches such as holmium laser enucleation of the prostate (HoLEP) have been introduced to relieve bladder outlet obstruction caused by benign prostatic hyperplasia (BPH). Compared with other techniques including the transurethral resection of the prostate (TURP) and simple open prostatectomy, HoLEP results in a shorter hospital stay and catheterization time and fewer blood loss and transfusions. HoLEP is a size-independent treatment option for BPH with average gland size from 36 g to 170 g. HoLEP is a safe procedure in patients receiving an anticoagulant and has no significant influence on the hemoglobin level. Also, HoLEP is an easy and safe technique in patients with a prior history of prostate surgery and a need for retreatment because of adenoma regrowth. The postoperative erectile dysfunction rate of patients treated with HoLEP is similar to TURP or open prostatectomy and about 77% of these patients experience loss of ejaculation. Patients with transitional zone volume less than 30 mL may suffer from persistent stress urinary incontinence following HoLEP so other surgical techniques like bipolar TURP are a good choice for these patients. In young patients, considering HoLEP with high prostate-specific antigen density and a negative standard template prostate biopsy, multiparametric MRI needs to be considered to exclude prostate cancer.

Keywords:
  • Laser
  • Minimal invasive
  • HoLEP
  • Prostate surgery
  • Prostate hyperplasia
  • Transurethral resection of prostate
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How to Cite

Abedi, A., Razzaghi, M. R., Rahavian, A., Hazrati, E., Aliakbari, F., Vahedisoraki, V., & Allameh, F. (2020). Is Holmium Laser Enucleation of Prostate a Good Surgical Alternative in Benign Prostatic Hyperplasia Management? A Review Article. Journal of Lasers in Medical Sciences, 11(2), 197–203. Retrieved from https://journals.sbmu.ac.ir/jlms/article/view/27942
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References

REFERENCE:

Chute CG, Panser LA, Girman CJ, Oesterling JE, Guess HA, Jacobsen SJ, et al. The prevalence of

prostatism: a population-based survey of urinary symptoms. J Urol. 1993;150(1):85-9. doi:

1016/s0022-5347(17)35405-8.

Guess HA, Arrighi HM, Metter EJ, Fozard JL. Cumulative prevalence of prostatism matches the

autopsy prevalence of benign prostatic hyperplasia. Prostate. 1990;17(3):241-6. doi:

1002/pros.2990170308.

Karami H, Hassanzadeh-Hadad A, Fallah-Karkan M. Comparing monotherapy with tadalafil or

tamsulosin and their combination therapy in men with benign prostatic hyperplasia: a randomized

clinical trial. Urol J. 2016;13(6):2920-6. doi: 10.22037/uj.v13i6.3666.

Shigemura K, Fujisawa M. Current status of holmium laser enucleation of the prostate. Int J Urol.

;25(3):206-11. doi: 10.1111/iju.13507.

Marien T, Kadihasanoglu M, Miller NL. Holmium laser enucleation of the prostate: patient

selection and perspectives. Res Rep Urol. 2016;8:181-92. doi: 10.2147/RRU.S100245.

Razzaghi MR, Fallah Karkan M, Ghiasy S, Javanmard B. Laser application in iran urology: a

narrative review. J Lasers Med Sci. 2018;9(1):1-6. doi: 10.15171/jlms.2018.01.

Razzaghi MR, Mazloomfard MM, Mokhtarpour H, Moeini A. Diode laser (980 nm) vaporization in

comparison with transurethral resection of the prostate for benign prostatic hyperplasia: randomized

clinical trial with 2-year follow-up. Urology. 2014;84(3):526-32. doi: 10.1016/j.urology.2014.05.027.

Sadeghi K, Hamishehkar H, Najmeddin F, Ahmadi A, Hazrati E, Honarmand H, et al. High-dose

amikacin for achieving serum target levels in critically ill elderly patients. Infect Drug Resist.

;11:223-8. doi: 10.2147/IDR.S150839.

Kahokehr AA, Gilling PJ. Which laser works best for benign prostatic hyperplasia? Curr Urol Rep.

;14(6):614-9. doi: 10.1007/s11934-013-0351-8.

Javanmard B, Fallah Karkan M, Razzaghi MR, Ghiasy S, Ranjbar A, Rahavian A. Surgical

management of vesical stones in children: a comparison between open cystolithotomy, percutaneous

cystolithotomy and transurethral cystolithotripsy with holmium-YAG Laser. J Lasers Med Sci.

;9(3):183-7. doi: 10.15171/jlms.2018.33.

Abedi AR, Razzaghi MR, Allameh F, Aliakbari F, Fallahkarkan M, Ranjbar A. Pneumatic Lithotripsy

Versus Laser Lithotripsy for Ureteral Stones. J Lasers Med Sci. 2018;9(4):233-6. doi:

15171/jlms.2018.42.

Ghiasy S, Fallah-Karkan M, Razzaghi MR, Ranjbar A, Rahavian A, Javanmard B. Is Holmium laser

an appropriate modality to treat genital warts? J Lasers Med Sci. 2019;10(1):70-74. doi:

15171/jlms.2019.11.

Fallah karkan M, Razzaghi MR, Karami H, Ghiasy S, Tayyebiazar A, Javanmard B. Experience of

transurethral urethrotomy with Holmium:YAG laser. J Lasers Med Sci. 2019;10(2):104-7. doi:

15171/jlms.2019.17.

Fallah Karkan M, Razzaghi MR, Javanmard B, Tayyebiazar A, Ghiasy S, Montazeri S. Holmium:

YAG Laser Incision of Bladder Neck Contracture Following Radical Retropubic Prostatectomy. Nephro-

Urol Mon. 2019;11(1):e88677. doi: 10.5812/numonthly.88677.

Mottet N, Anidjar M, Bourdon O, Louis JF, Teillac P, Costa P, et al. Randomized comparison of

transurethral electroresection and holmium: YAG laser vaporization for symptomatic benign prostatic

hyperplasia. J Endourol. 1999;13(2):127-30. doi: 10.1089/end.1999.13.127.

Fallah Karkan M, Ghiasy S, Ranjbar A, Javanmard B. Evaluation of 200 Mm, 365 Mm and 500 Mm

fibers of Ho: YAG laser in transurethral lithotripsy of ureteral: a randomize control trial. J Lasers Med Sci.

;9(1):69-72. doi: 10.15171/jlms.2018.14.

Abedi AR, Allameh F, Razzaghi MR, Fadavi B, Qashqai H, Najafi S, et al. The efficacy and safety of

laser lithotripsy in pregnancy. J Lasers Med Sci. 2017;8(2):84-7. doi: 10.15171/jlms.2017.15.

Elshal AM, El-Nahas AR, Ghazy M, Nabeeh H, Laymon M, Soltan M, et al. Low-Power Vs High-

Power Holmium Laser Enucleation of the Prostate: Critical Assessment through Randomized Trial.

Urology. 2018;121:58-65. doi: 10.1016/j.urology.2018.07.010.

Xu C, Xu Z, Lin C, Feng S, Sun M, Chen J, et al. Holmium laser enucleation of the prostate:

Modified two-Lobe technique versus traditional three-Lobe technique—A randomized study. Biomed

Res Int. 2019;2019:3875418. doi: 10.1155/2019/3875418.

Kuo RL, Paterson RF, Kim SC, Siqueira TM Jr, Elhilali MM, Lingeman JE. Holmium Laser

Enucleation of the Prostate (HoLEP): A Technical Update. World J Surg Oncol. 2003;1(1):6. doi:

1186/1477-7819-1-6.

Humphreys MR, Miller NL, Handa SE, Terry C, Munch LC, Lingeman JE. Holmium laser

enucleation of the prostate—outcomes independent of prostate size? J Urol. 2008;180(6):2431-5. doi:

1016/j.juro.2008.08.019.

Shah HN, Sodha HS, Kharodawala SJ, Khandkar AA, Hegde SS, Bansal MB. Influence of prostate

size on the outcome of holmium laser enucleation of the prostate. BJU Int. 2008;101(12):1536-41. doi:

1111/j.1464-410X.2007.07434.x.

Seki N, Tatsugami K, Naito S. Holmium laser enucleation of the prostate: comparison of

outcomes according to prostate size in 97 Japanese patients. J Endourol. 2007;21(2):192-6. doi:

1089/end.2006.0123.

Kim KS, Choi JB, Bae WJ, Kim SJ, Cho HJ, Hong SH, et al. Comparison of Photoselective

Vaporization versus holmium laser enucleation for treatment of benign prostate hyperplasia in a small

prostate volume. PLoS One. 2016;11(5):e0156133. doi: 10.1371/journal.pone.0156133.

Krambeck AE, Handa SE, Lingeman JE. Holmium laser enucleation of the prostate for prostates

larger than 175 grams. J Endourol. 2010;24(3):433-7. doi: 10.1089/end.2009.0147.

Matlaga BR, Kim SC, Kuo RL, Watkins SL, Lingeman JE. Holmium laser enucleation of the prostate

for prostates of > 125 mL. BJU Int. 2006;97(1):81-4. doi: 10.1111/j.1464-410X.2006.05898.x.

Kuntz RM, Lehrich K, Ahyai SA. Holmium laser enucleation of the prostate versus open

prostatectomy for prostates greater than 100 grams: 5-year follow-up results of a randomised clinical

trial. Eur Urol. 2008;53(1):160-8. doi: 10.1016/j.eururo.2007.08.036.

Naspro R, Suardi N, Salonia A, Scattoni V, Guazzoni G, Colombo R, et al. Holmium laser

enucleation of the prostate versus open prostatectomy for prostates > 70 g: 24-month follow-up. Eur

Urol. 2006;50(3):563-8. doi: 10.1016/j.eururo.2006.04.003.

Wisenbaugh ES, Nunez-Nateras R, Mmeje CO, Warner JN, Humphreys MR. Does prostate

morphology affect outcomes after holmium laser enucleation? Urology. 2013;81(4):844-8. doi:

1016/j.urology.2013.01.006.

Gerridzen RG, Futter NG. Ten-year review of vesical diverticula. Urology. 1982;20(1):33-5. doi:

1016/0090-4295(82)90532-5.

Agarwal DK, Krambeck AE. Holmium laser enucleation of the prostate is an effective treatment

in patients with concomitant bladder diverticula and outlet obstruction. World J Urol. 2018;36(1):87-90.

doi: 10.1007/s00345-017-2114-5.

Douketis JD, Spyropoulos AC, Spencer FA, Mayr M, Jaffer AK, Eckman MH, et al. Perioperative

management of antithrombotic therapy: antithrombotic therapy and prevention of thrombosis:

American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2012;141(2

Suppl):e326S-e350S. doi: 10.1378/chest.11-2298.

Romero-Otero J, García-González L, García-Gómez B, Justo-Quintas J, García-Rojo E, González-

Padilla DA, et al. Factors influencing intraoperative blood loss in patients undergoing Holmium Laser

Enucleation of the Prostate (HoLEP) for Benign Prostatic Hyperplasia: a large multicenter analysis.

Urology. 2019. doi: 10.1016/j.urology.2019.06.024.

De Caterina R, Husted S, Wallentin L, Andreotti F, Arnesen H, Bachmann F, et al. General

mechanisms of coagulation and targets of anticoagulants (section I). Position paper of the ESCworking

group on thrombosis--task force on anticoagulants in heart disease. Thromb Haemost. 2013;109(4):569-

doi: 10.1160/TH12-10-0772.

Dall M, Primdahl A, Damborg F, Nymark T, Hallas J. The association between use of serotonergic

antidepressants and perioperative bleeding during total hip arthroplasty–a cohort study. Basic Clin

Pharmacol Toxicol. 2014;115(3):277-81. doi: 10.1111/bcpt.12218.

Gilling PJ, Wilson LC, King CJ, Westenberg AM, Frampton CM, Fraundorfer MR. Long‐term results

of a randomized trial comparing holmium laser enucleation of the prostate and transurethral resection

of the prostate: results at 7 years. BJU Int. 2012;109(3):408-11. doi: 10.1111/j.1464-410X.2011.10359.x.

Gilling PJ, Aho TF, Frampton CM, King CJ, Fraundorfer MR. Holmium laser enucleation of the

prostate: results at 6 years. Eur Urol. 2008;53(4):744-9. doi: 10.1016/j.eururo.2007.04.052.

Elshal AM, Elmansy HM, Elhilali MM. Feasibility of holmium laser enucleation of the prostate

(HoLEP) for recurrent/residual benign prostatic hyperplasia (BPH). BJU Int. 2012;110(11 Pt C):E845-E50.

doi: 10.1111/j.1464-410X.2012.11290.x.

Marien T, Kadihasanoglu M, Tangpaitoon T, York N, Blackburne A, Abdul-Muhsin H, et al. MP42-

Outcomes of HoLEP performed in the retreatment setting. J Urol. 2016;195(4S):e571-e572.

doi.org/10.1016/j.juro.2016.12.098

Rosen R, Altwein J, Boyle P, Kirby RS, Lukacs B, Meuleman E, et al. Lower urinary tract symptoms

and male sexual dysfunction: the multinational survey of the aging male (MSAM-7). Eur Urol.

;44(6):637-49. doi: 10.1016/j.eururo.2003.08.015.

Soderdahl DW, Knight RW, Hansberry KL. Erectile dysfunction following transurethral resection

of the prostate. J Urol. 1996;156(4):1354-6. doi: 10.1016/S0022-5347(01)65585-X.

Tscholl R, Largo M, Poppinghaus E, Recker F, Subotic B. Incidence of erectile impotence

secondary to transurethral resection of benign prostatic hyperplasia, assessed by preoperative and

postoperative Snap Gauge tests. J Urol. 1995;153(5):1491-3. doi: 10.1016/S0022-5347(01)67442-1.

Hanbury DC, Sethia KK. Erectile function following transurethral prostatectomy. Br J Urol.

;75(1):12-3. doi: 10.1111/j.1464-410x.1995.tb07224.x.

Montorsi F, Naspro R, Salonia A, Suardi N, Briganti A, Zanoni M, et al. Holmium laser enucleation

versus transurethral resection of the prostate: results from a 2-center prospective randomized trial in

patients with obstructive benign prostatic hyperplasia. J Urol. 2008;179(5 Suppl):S87-S90. doi:

1016/j.juro.2008.03.143.

Naspro R, Bachmann A, Gilling P, Kuntz R, Madersbacher S, Montorsi F, et al. A review of the

recent evidence (2006–2008) for 532-nm photoselective laser vaporisation and holmium laser

enucleation of the prostate. Eur Urol. 2009;55(6):1345-57. doi: 10.1016/j.eururo.2009.03.070.

Kim JK, Cho MC, Son H, Ku JH, Oh S-J, Paick JS. Patient perception of ejaculatory volume

reduction after holmium laser enucleation of the prostate (HoLEP). Urology. 2017;99:142-7. doi:

1016/j.urology.2016.09.037.

Briganti A, Naspro R, Gallina A, Salonia A, Vavassori I, Hurle R, et al. Impact on sexual function of

holmium laser enucleation versus transurethral resection of the prostate: results of a prospective, 2-

center, randomized trial. J Urol. 2006;175(5):1817-21. doi: 10.1016/S0022-5347(05)00983-3.

Serretta V, Morgia G, Fondacaro L, Curto G, Lo bianco A, Pirritano D, et al. Open prostatectomy

for benign prostatic enlargement in southern Europe in the late 1990s: a contemporary series of 1800

interventions. Urology. 2002;60(4):623-7. doi: 10.1016/s0090-4295(02)01860-5.

Tubaro A, Carter S, Hind A, Vicentini C, Miano L. A prospective study of the safety and efficacy of

suprapubic transvesical prostatectomy in patients with benign prostatic hyperplasia. J Urol.

;166(1):172-6. doi: 10.1016/S0022-5347(05)66102-2.

Kuntz RM, Lehrich K, Ahyai S. Does perioperative outcome of transurethral holmium laser

enucleation of the prostate depend on prostate size? J Endourol. 2004;18(2):183-8. doi:

1089/089277904322959842.

Seki N, Mochida O, Kinukawa N, Sagiyama K, Naito S. Holmium laser enucleation for prostatic

adenoma: analysis of learning curve over the course of 70 consecutive cases. J Urol. 2003;170(5):1847-

doi: 10.1097/01.ju.0000092035.16351.9d.

Cho KJ, Koh JS, Choi JB, Kim JC. Factors associated with early recovery of stress urinary

incontinence following holmium laser enucleation of the prostate in patients with benign prostatic

enlargement. Int Neurourol J. 2018;22(3):200-205. doi: 10.5213/inj.1836092.046.

Endo F, Shiga Y, Minagawa S, Iwabuchi T, Fujisaki A, Yashi M, et al. Anteroposterior dissection

HoLEP: a modification to prevent transient stress urinary incontinence. Urology. 2010;76(6):1451-5. doi:

1016/j.urology.2010.03.071.

Walz J, Burnett AL, Costello AJ, Eastham JA, Graefen M, Guillonneau B, et al. A critical analysis of

the current knowledge of surgical anatomy related to optimization of cancer control and preservation of

continence and erection in candidates for radical prostatectomy. Eur Urol. 2010;57(2):179-92. doi:

1016/j.eururo.2009.11.009.

Jones JS. Saturation biopsy for detecting and characterizing prostate cancer. BJU Int.

;99(6):1340-4. doi: 10.1111/j.1464-410X.2007.06868.x.

Serefoglu EC, Altinova S, Ugras NS, Akincioglu E, Asil E, Balbay MD. How reliable is 12-core

prostate biopsy procedure in the detection of prostate cancer? Can Urol Assoc J. 2013;7(5-6):E293-8.

doi: 10.5489/cuaj.11224.

Abedi AR, Fallah-Karkan M, Allameh F, Ranjbar A, Shadmehr A. Incidental prostate cancer: a 10-

year review of a tertiary center, Tehran, Iran. Res Rep Urol. 2018;10:1-6. doi: 10.2147/RRU.S146159.

Jamali L, Moradi A, Ganji M, Ayati M, Kazeminezhad B, Fazeli Attar Z, et al. Potential Prognostic

Role for SPOP, DAXX, RARRES1, and LAMP2 as an Autophagy Related Genes in Prostate Cancer. Urol J.

doi: 10.22037/uj.v0i0.4935.

Rivera ME, Frank I, Viers BR, Rangel LJ, Krambeck AE. Holmium laser enucleation of the prostate

and perioperative diagnosis of prostate cancer: an outcomes analysis. J Endourol. 2014;28(6):699-703.

doi: 10.1089/end.2014.0009.

Elkoushy MA, Elshal AM, Elhilali MM. Incidental prostate cancer diagnosis during holmium laser

enucleation: assessment of predictors, survival, and disease progression. Urology. 2015;86(3):552-7. doi:

1016/j.urology.2015.06.002.

Ghiasy S, Abedi AR, Moradi A, Hosseini SY, Karkan MF, Sadri G, et al. Is active surveillance an

appropriate approach to manage prostate cancer patients with Gleason Score 3+3 who met the criteria

for active surveillance? Turk J Urol. 2018;45(4):261-4. doi: 10.5152/tud.2018.72920.

Porreca A, Giampaoli M, Bianchi L, D'Agostino D, Romagnoli D, Bianchi FM, et al. Preoperative

multiparametric prostate magnetic resonance imaging: a safe clinical practice to reduce incidental

prostate cancer in Holmium laser enucleation of the prostate. Cent European J Urol.2019;72(2):106-112.

doi: 10.5173/ceju.2019.1943.

Gellhaus PT, Monn MF, Leese J, Flack CK, Lingeman JE, Koch MO, et al. Robot-assisted radical

prostatectomy in patients with a history of holmium laser enucleation of the prostate: feasibility and

evaluation of initial outcomes. J Endourol. 2015;29(7):764-9. doi: 10.1089/end.2014.0767.

Tan A, Liao C, Mo Z, Cao Y. Meta‐analysis of holmium laser enucleation versus transurethral

resection of the prostate for symptomatic prostatic obstruction. Br J Surg. 2007;94(10):1201-8. doi:

1002/bjs.5916.

Yin L, Teng J, Huang CJ, Zhang X, Xu D. Holmium laser enucleation of the prostate versus

transurethral resection of the prostate: a systematic review and meta-analysis of randomized controlled

trials. J Endourol. 2013;27(5):604-11. doi: 10.1089/end.2012.0505.

Naqvi SA, Rizvi S, Hasan A. High-energy microwave thermotherapy in patients in urinary

retention. J Endourol. 2000;14(8):677-81. doi: 10.1089/end.2000.14.677.

Ahyai SA, Gilling P, Kaplan SA, Kuntz RM, Madersbacher S, Montorsi F, et al. Meta-analysis of

functional outcomes and complications following transurethral procedures for lower urinary tract

symptoms resulting from benign prostatic enlargement. Eur Urol. 2010;58(3):384-97. doi:

1016/j.eururo.2010.06.005.

Elmansy H, Baazeem A, Kotb A, Badawy H, Riad E, Emran A, et al. Holmium laser enucleation

versus photoselective vaporization for prostatic adenoma greater than 60 ml: preliminary results of a

prospective, randomized clinical trial. J Urol. 2012;188(1):216-21. doi: 10.1016/j.juro.2012.02.2576.

Elmansy HM, Kotb A, Elhilali MM. Holmium laser enucleation of the prostate: long-term

durability of clinical outcomes and complication rates during 10 years of followup. J Urol.

;186(5):1972-6. doi: 10.1016/j.juro.2011.06.065.

Gupta N, Sivaramakrishna, Kumar R, Dogra PN, Seth A. Comparison of standard transurethral

resection, transurethral vapour resection and holmium laser enucleation of the prostate for managing

benign prostatic hyperplasia of > 40 g. BJU Int. 2006;97(1):85-9. doi: 10.1111/j.1464-410X.2006.05862.x.

Cornu JN, Ahyai S, Bachmann A, de la Rosette J, Gilling P, Gratzke C, et al. A systematic review

and meta-analysis of functional outcomes and complications following transurethral procedures for

lower urinary tract symptoms resulting from benign prostatic obstruction: an update. Eur Urol.

;67(6):1066-96. doi: 10.1016/j.eururo.2014.06.017.

Bae J, Oh SJ, Paick JS. The learning curve for holmium laser enucleation of the prostate: a single-

center experience. Korean J Urol. 2010;51(10):688-93. doi: 10.4111/kju.2010.51.10.688.

Kampantais MS, Dimopoulos MP, Tasleem MA, Acher MP, Gordon MK, Young A. Assessing the

learning curve of Holmium Laser Enucleation of Prostate (HoLEP). A systematic review. Urology. 2018.

doi: 10.1016/j.urology.2018.06.012.

Lourenco T, Armstrong N, N'Dow J, Nabi G, Deverill M, Pickard R, et al. Systematic review and

economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic

enlargement. Health Technol Assess. 2008;12(35):iii, ix-x, 1-146, 169-515. doi: 10.3310/hta12350.

Mavuduru RM, Mandal AK, Singh SK, Acharya N, Agarwal M, Garg S, et al. Comparison of HoLEP

and TURP in terms of efficacy in the early postoperative period and perioperative morbidity. Urol Int.

;82(2):130-5. doi: 10.1159/000200786.

Kuntz RM, Lehrich K, Ahyai S. Transurethral holmium laser enucleation of the prostate compared

with transvesical open prostatectomy: 18-month follow-up of a randomized trial. J Endourol.

;18(2):189-91. doi: 10.1089/089277904322959851.

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