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Medication-Related Osteonecrosis of the Jaw and Low-Level Laser Therapy as Adjuvant Treatment: A Case Report

  • Amanda Azevedo Torres
  • Beatriz Leal de Freitas
  • Patrick Parry Carneiro
  • André Luca Araujo de Sousa
  • Maria Ângela Arêa Leão Ferraz
  • Jean de Pinho Mendes
  • André Luiz Ferreira Costa
  • Antonione Santos Bezerra Pinto

Journal of Lasers in Medical Sciences, Vol. 11 No. 4 (2020), , Page 497-499
Published 3 October 2020

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Abstract

Introduction: Medication-related osteonecrosis of the jaw (MRONJ) occurs by the use of a drug that has osteonecrosis as one of its side effects.
Case Report: We describe a case of a 48-year-old oncological patient who had brain and bone metastasis due to breast cancer and was medicated with bisphosphonates (BPs). She presented cavities, and after an incorrect exodontia, the lesion evolved into jaw osteonecrosis. Then she did a sequestrectomy and was treated using laser therapy. Radiological and clinical features are also described.
Conclusion: In a case like this, we notice how necessary is a complete evaluation of the oncological patient before some procedures and laser therapy as an effective ally in the management.

Keywords:
  • Bisphosphonate-Associated Osteonecrosis of the Jaw
  • Laser Therapy
  • Low-Level Light Therapy.
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How to Cite

Torres, A. A., de Freitas, B. L., Carneiro, P. P., de Sousa, A. L. A., Ferraz, M. Ângela A. L., Mendes, J. de P., Costa, A. L. F., & Pinto, A. S. B. (2020). Medication-Related Osteonecrosis of the Jaw and Low-Level Laser Therapy as Adjuvant Treatment: A Case Report. Journal of Lasers in Medical Sciences, 11(4), 497-499. Retrieved from https://journals.sbmu.ac.ir/jlms/article/view/27881
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References

Ruggiero SL, Dodson TB, Fantasia J, Goodday R, Aghaloo T, Mehrotra B, et al. American association of oral and maxillofacial surgeons position paper on medication-related osteonecrosis of the jaw—2014 update. J Oral Maxillofac Surg. 2014;72(10):1938-1956. doi: 10.1016/j.joms.2014.04.031.

Ellis E III. Management of the patient undergoing radiotherapy or chemotherapy. In: Hupp JR, Tucker MR, Ellis E III. Contemporary oral and maxillofacial surgery. 6th ed. St. Louis, Missouri: Mosby; 2013. P. 363-381.

Borromeo GL, Tsao CE, Darby IB, Ebeling PR. A review of the clinical implications of bisphosphonates in dentistry. Aust Dent J. 2011;56(1):2-9. doi:10.1111/j.1834-7819.2010.01283.x

Cortés-Motta MC, Fernández-Grisales R. Osteonecrosis de los maxilares: fisiopatología, diagnóstico y tratamiento. CES Odont. 2016;29(2):65-77. [In Spanish].

Campos Scarpa L, de Mello Leite LC, de Lacerda JCT, Barreto Arantes DC. Osteonecrose nos ossos da maxila e mandíbula associada ao uso do bisfosfonato de sódio. Revista Brasileira de Pesquisa em Saúde. 2010;12(1):86-92. [In Portuguese].

Neville BW, Damm DD, Allen CM, Chi AC. Oral and Maxillofacial Pathology. 4th ed. St. Louis, Missouri: Elsevier; 2016.

Latifyan S, Genot MT, Klastersky J. Bisphosphonate-related osteonecrosis of the jaw: a review of the potential efficacy of low-level laser therapy. Support Care Cancer. 2016;24(9):3687-93. doi: 10.1007/s00520-016-3139-9.

Minamisako MC, Ribeiro GH, Lisboa ML, Rodríguez Cordeiro MM, Grando LJ. Medication-related osteonecrosis of jaws: A low-level laser therapy and antimicrobial photodynamic therapy case approach. Case Rep Dent. 2016;2016:6267406. doi: 10.1155/2016/6267406.

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