Evaluation of Topical Capislow Extract and Long Pulsed Nd-YAG Laser in the Treatment of Idiopathic Hirsutism
Journal of Lasers in Medical Sciences,
Vol. 9 No. 2 (2018),
27 April 2018
,
Page 128-133
Abstract
Introduction: Hirsutism is a condition that affects 10% of women worldwide. In many cultures, hirsutism is regarded as loss of femininity and can be psychologically traumatizing to the suffering females. The aim of the present study was to evaluate how topical capislow would affect or enhance the efficacy of laser hair removal.
Methods: A randomized, monoblinded, placebo controlled split face study of combined topical capislow and long pulsed Nd-YAG laser on one side of the face versus long pulsed Nd-YAG laser alone on the opposite side of the face. Laser sessions were done at 4 weeks interval for maximum seven sessions. Topical capislow and placebo were applied once daily from the day of the first laser session to the day of the last laser session. Patients were evaluated both subjectively and objectively in each laser session and for six months after the last laser session.
Results: Both treatment modalities were well tolerated and accepted with significantly better results in combined capislow and laser group versus laser alone.
Conclusion: Topical capislow can represent a safe and effective synergistic method for laser with faster results but this is a temporary effect retained only to the time of its application.
- laser hair removal
- NdYAG
- capsilow
How to Cite
References
Sahin Y, Kelestimur F. Medical treatment regimens of hirsutism. Reprod Biomed Online. 2004;8(5):538-546.
Blume-Peytavi U, Gieler U, Hoffmann R, Lavery S, Shapiro J. Unwanted facial hair: affects, effects and solutions. Dermatology. 2007;215(2):139-146. doi:10.1159/000104266
Watts J. Understanding the causes and management of hirsutism. Nurs Times. 2006;102(8):26-28.
Hunter MH, Carek PJ. Evaluation and treatment of women with hirsutism. Am Fam Physician. 2003;67(12):2565-2572.
Nouri K, Vejjabhinanta V, Patel SS, Singh A. Photoepilation: a growing trend in laser-assisted cosmetic dermatology. J Cosmet Dermatol. 2008;7(1):61-67. doi:10.1111/j.1473- 2165.2008.00363.x
Hiipakka RA, Zhang HZ, Dai W, Dai Q, Liao S. Structure-activity relationships for inhibition of human 5alpha-reductases by polyphenols. Biochem Pharmacol. 2002;63(6):1165-1176.
Lepselter J, Elman M. Biological and clinical aspects in laser hair removal. J Dermatolog Treat. 2004;15(2):72-83. doi:10.1080/09546630310023152
Haedersdal M, Wulf HC. Evidence-based review of hair removal using lasers and light sources. J Eur Acad Dermatol Venereol. 2006;20(1):9-20. doi:10.1111/j.1468- 3083.2005.01327.x
Casey AS, Goldberg D. Guidelines for laser hair removal. J Cosmet Laser Ther. 2008;10(1):24-33. doi:10.1080/14764170701817049
Hamzavi I, Tan E, Shapiro J, Lui H. A randomized bilateral vehicle-controlled study of eflornithine cream combined with laser treatment versus laser treatment alone for facial hirsutism in women. J Am Acad Dermatol. 2007;57(1):54- 59. doi:10.1016/j.jaad.2006.09.025
Yildiz BO, Bolour S, Woods K, Moore A, Azziz R. Visually scoring hirsutism. Hum Reprod Update. 2010;16(1):51-64. doi:10.1093/humupd/dmp024
Keegan A, Liao LM, Boyle M. ‘Hirsutism’: a psychological analysis. J Health Psychol. 2003;8(3):327-345. doi:10.1177/13591053030083004
Goh CL. Comparative study on a single treatment response to long pulse Nd:YAG lasers and intense pulse light therapy for hair removal on skin type IV to VI--is longer wavelengths lasers preferred over shorter wavelengths lights for assisted hair removal. J Dermatolog Treat. 2003;14(4):243-247. doi:10.1080/09546630310004171
Azziz R, Carmina E, Sawaya ME. Idiopathic hirsutism. Endocr Rev. 2000;21(4):347-362. doi:10.1210/ edrv.21.4.0401
Dierickx CC. Laser hair removal. In: Kauvar A, Hruza G, eds. Principles and Practices in Cutaneous Laser Surgery. Taylor and Francis group; 2005:677-701.
Gold MH. Lasers and light sources for the removal of unwanted hair. Clin Dermatol. 2007;25(5):443-453. doi:10.1016/j.clindermatol.2007.05.017
Anesini C, Ferraro G, Lopez P, Borda E. Different intracellular signals coupled to the antiproliferative action of aqueous crude extract from Larrea divaricata Cav. and nor-dihydroguaiaretic acid on a lymphoma cell line. Phytomedicine. 2001;8(1):1-7. doi:10.1078/0944-7113- 00006
Zhu HX, Hu JA. [Advances in the research of lipoxygenase inhibitors]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2008;33(6):541-547.
Bracco MM. Hirsutism. Clin Exp Immunol. 1984;55:405.
Stickel F, Egerer G, Seitz HK. Hepatotoxicity of botanicals. Public Health Nutr. 2000;3(2):113-124.
- Abstract Viewed: 701 times
- PDF Downloaded: 399 times