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International Journal of Medical Toxicology and Forensic Medicine

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  3. Vol. 13 No. 3 (2023): International Journal of Medical Toxicology and Forensic Medicine
  4. Original Article (General Medicine)

Vol. 13 No. 3 (2023)

October 2023

Side Effects of COVID-19 Vaccination Among Healthcare Workers in Tehran, Iran Side effects after COVID-19 vaccination

  • Davood Yadegarynia
  • Shabnam Tehrani
  • Fahimeh Hadavand
  • Shahnam Arshi
  • Zahra Abtahian
  • Amirreza Keyvanfar
  • Azar Darvishi
  • Afshin Zarghi

International Journal of Medical Toxicology and Forensic Medicine, Vol. 13 No. 3 (2023), 17 October 2023
https://doi.org/10.32598/ijmtfm.v13i3.40536 Published: 09/30/2023 — Updated on 09/30/2023

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Abstract

Background: Since the emergence of coronavirus disease 2019 (COVID-19), many people have been vaccinated worldwide. Despite the preventive role of vaccines, their side effects face disease management with challenges. This study aims to investigate the side effects of COVID-19 vaccination among healthcare workers in Tehran, Iran.
Methods: This cross-sectional study was conducted from April to October 2022 on 377 healthcare workers in Tehran, Iran. Data collection was carried out through an interview by a researcher using a checklist assessing systemic and local side effects of COVID-19 vaccines.
Results: The mean age of participants was 36.03±10.24 years, and 68.2% were female. Participants experienced significantly more local (26.5% vs. 14.3%, P<0.001) and systemic (52.0% vs. 31.8%, P<0.001) side effects after the first dose than after the second dose. After the first dose, AstraZeneca (45.9%) caused significantly more local reactions than Sputnik V (21.7%) and Sinopharm (14.5%). AstraZeneca (83.7%) caused significantly more systemic side effects than Sputnik V (50.7%) and Sinopharm (14.5%). The prevalence of local and systemic side effects after the first dose was significantly different in terms of vaccine types (P<0.001). After the second dose, AstraZeneca (20.4%) caused significantly more local reactions than Sputnik V (12.8%) and Sinopharm (10.5%) (P<0.001). Additionally, AstraZeneca (38.8%) and Sputnik V (37.4%) caused significantly more systemic side effects than Sinopharm (7.9%) (P<0.001).
Conclusion: Most healthcare workers in Tehran experienced flu-like symptoms and local reactions at the injection site after vaccination against COVID-19, mainly after the first dose. They had more side effects after vaccination with AstraZeneca and Sputnik V, compared to Sinopharm.

Keywords:
  • Adverse effects
  • COVID-19 vaccines
  • Iran
  • Safety
  • SARS-CoV-2
  • 09/30/2023 (2)
  • 09/30/2023 (1)
  • pdf

How to Cite

Yadegarynia, D., Tehrani, S., Hadavand, F., Arshi, S., Abtahian, Z., Keyvanfar, A., … Zarghi, A. (2023). Side Effects of COVID-19 Vaccination Among Healthcare Workers in Tehran, Iran: Side effects after COVID-19 vaccination . International Journal of Medical Toxicology and Forensic Medicine, 13(3). https://doi.org/10.32598/ijmtfm.v13i3.40536
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