Primary follicular lymphoma of the duodenum: A case report and review of literatures
Gastroenterology and Hepatology from Bed to Bench,
8 March 2021
Follicular lymphoma (FL) is one of the most common types of non-Hodgkin lymphoma (NHL). The gastrointestinal tract is the most involved extra-nodal site of NHL. However, primary duodenal FL (DFL), is a rare entity, with only a few reported cases, mainly involve second part of the duodenum and have an excellent prognosis. We report the case of a 74-year-old man underwent esophagogastroduodenoscopy. Endoscopic finding revealed multiple small whitish mucosal nodules were detected around the major duodenal papilla. Biopsy of these lesions compatible with grade I FL. Further investigation failed to demonstrate any evidence of nodal or systemic involvement, thus, the clinical staging was stage I, according to the Lugano staging system. A “watch and wait” policy was chosen. Neither lesion aggregation nor lymphadenopathy was noted during the 5-year follow-up period. In conclusion, this was an uncommon case of DFL, which behave indolent nature and excellent prognosis. However, further studies are needed to clarify characteristics, prognosis, and therapeutic approach.
- follicular lymphoma
- lymph node
- non-Hodgkin lymphoma
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