Evaluating the Effect of Botulinum Toxin on Visual Pathway Measured by Visual Evoked Potential Using Flash and Pattern Reversal Checkerboard Stimulation Techniques
Journal of Ophthalmic and Optometric Sciences,
Vol. 7 No. 3 (2023),
17 July 2024,
Page 1-4
https://doi.org/10.22037/joos.v7i3.45808
Purpose: The aim of the present study was to investigate possible side effects of botulinum toxin on the visual pathway, measured by visual evoked potentials using two stimulation techniques: flash and pattern reversal checkerboard.
Patients and Methods: Twenty-six eyes from thirteen female subjects, aged between 40 and 52 years, who received botulinum toxin injections for cosmetic purposes in the upper face area, comprised the case group. Visual evoked potentials using two stimulation techniques (flash and pattern reversal checkerboard) were measured in this group. The obtained results were compared with those of 26 eyes from 13 healthy females with no history of botulinum toxin, who formed the control group.
Results: A significant difference was observed in the latency of the flash visual evoked potential P100 peak between the case and control groups (P<0.001) when using the flash stimulation technique.
Conclusion: Botulinum toxin may affect the visual pathway of patients, which can be measured using flash visual evoked potentials.