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  3. 卷 8 编号 1 (2020): Continuous volume
  4. Case Report

卷 8 编号 1 (2020)

一月 2020

Henna-induced Hemolysis and Acute Kidney Injury in an 85-year-old Man; a Case Report

  • Sahel Asgari
  • Mohsen Esfandbod
  • Maryam Haghshomar

学术急诊医学档案, 卷 8 编号 1 (2020), 1 一月 2020 , 第 e82 页
https://doi.org/10.22037/aaem.v8i1.849 已出版: 2020-10-14

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摘要

Henna is a commonly used traditional cosmetic agent, which also holds medical potentials and is used to treat skin lesions including seborrheic dermatitis or fungal infections and also has possible anti-inflammatory effects. It contains lawsone (2-hydroxy-1,4-naphthoquinone) and, therefore, has the potential to induce oxidative hemolysis. Henna-induced hemolysis has been previously reported in children with Glucose 6-Phosphate Dehydrogenase Deficiency. Here, we report an 85-year-old man who developed hemolytic anemia and acute kidney injury following oral consumption of henna to help his dyspnea. He was treated with hydration, bicarbonate, and dexamethasone. Over the course of hospitalization, the patient developed ventilator-associated pneumonia and was treated with antibiotic. He was discharged after one month. This finding is of high importance due to common use of henna, especially among people with false beliefs regarding traditional and herbal medicine, and highlights the role of a full history taking.

关键词:
  • Case reports; hemolysis; Lawsonia plant; toxicity; herbal medicine; anemia, hemolytic; acute kidney injury
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Asgari S, Esfandbod M, Haghshomar M. Henna-induced Hemolysis and Acute Kidney Injury in an 85-year-old Man; a Case Report . Arch Acad Emerg Med [网际网络]. 2020年10月14日 [见引于 2026年7月7日];8(1):e82. 载于: https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/849
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参考

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Garratty G. Drug-induced immune hemolytic anemia. Hematology. 2009;2009(1):73-9.

SNAPPER I, MARKS D, SCHWARTZ L, HOLLANDER L. Hemolytic anemia secondary to mesantoin. Annals of internal medicine. 1953;39(3):619-23.

Sarkar R, Philip J, Mallhi R, Jain N. Drug-induced immune hemolytic anemia (Direct Antiglobulin Test positive). Medical Journal, Armed Forces India. 2013;69(2):190.

Lee HW, Kim H, Ryuk JA, Kil K-J, Ko BS. Hemopoietic effect of extracts from constituent herbal medicines of Samul-tang on phenylhydrazine-induced hemolytic anemia in rats. International journal of clinical and experimental pathology. 2014;7(9):6179.

Devecioğlu C, Katar S, Doğru O, Taş M. Henna-induced hemolytic anemia and acute renal failure. The Turkish journal of pediatrics. 2001;43(1):65-6.

Raupp P, Hassan JA, Varughese M, Kristiansson B. Henna causes life threatening haemolysis in glucose-6-phosphate dehydrogenase deficiency. Archives of disease in childhood. 2001;85(5):411-2.

Zinkham WH, Oski FA. Henna: a potential cause of oxidative hemolysis and neonatal hyperbilirubinemia. Pediatrics. 1996;97(5):707-9.

McMillan DC, Sarvate SD, Oatis Jr JE, Jollow DJ. Role of oxidant stress in lawsone-induced hemolytic anemia. Toxicological Sciences. 2004;82(2):647-55.

Gude D, Bansal DP, Ambegaonkar R, Prajapati J. Paraphenylenediamine: Blackening more than just hair. Journal of research in medical sciences: the official journal of Isfahan University of Medical Sciences. 2012;17(6):584.

Seyedzadeh A, Hemmati M, Gheiny S. Henna-induced severe hemolysis: In glucose 6-phosphate dehydrogenase deficiency. Pakistan Journal of Medical Sciences. 2007;23(1):119.

Ilkhanipur H, Hakimian N. Henna: A cause of life threatening hemolysis in G6PD-deficient patient. Pak J Med Sci. 2013;29(1 Suppl):429-31.

Kheir A, Gaber I, Gafer S, Ahmed W. Life-threatening haemolysis induced by henna in a Sudanese child with glucose-6-phosphate dehydrogenase deficiency. EMHJ. 2017;23(1).

Qurashi HE, Qumqumji AA, Zacharia Y. Acute renal failure and intravascular hemolysis following henna ingestion. Saudi Journal of Kidney Diseases and Transplantation. 2013;24(3):553.

Perinet I, Lioson E, Tichadou L, Glaizal M, de Haro L. Hemolytic anemia after voluntary ingestion of henna (Lawsonia inermis) decoction by a young girl with G6PD deficiency. Medecine tropicale: revue du Corps de sante colonial. 2011;71(3):292-4.

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