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学术急诊医学档案

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  3. 卷 8 编号 1 (2020): Continuous volume
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卷 8 编号 1 (2020)

一月 2020

Discriminatory precision of renal angina index in prediction of acute kidney injury in children: a systematic review and meta-analysis

  • Arash Abbasi
  • Pardis Mehdipour Rabori
  • Ramtin Farajollahi
  • Kosar Mohammad Ali
  • Nematollah Ataei
  • Mahmoud Yousefifard
  • Mostafa Hosseini

学术急诊医学档案, 卷 8 编号 1 (2020), 1 一月 2020 , 第 e39 页
https://doi.org/10.22037/aaem.v8i1.585 已出版: 2020-03-30

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摘要

Introduction: There is still controversy over the value of renal angina index (RAI) in predicting acute renal failure (AKI) in children. Therefore, the present study aims to provide evidence by conducting a systematic review and meta-analysis on the value of RAI in this regard.

Methods: An extensive search of Medline, Embase, Scopus and Web of Science databases was conducted by the end of January 2020 using words related to RAI and AKI. Two independent reviewers screened and summarized the related studies. Data were analysed using STATA 14.0 statistical program and discriminatory precision of RAI was assessed.

Results: Data from 11 studies were included. These studies included data from 3701 children (60.41% boys). There were 752 children with AKI and 2949 non-AKI children. Pooled analysis showed that the area under the ROC curve of RAI in prediction of AKI was 0.88 [95% confidence interval (CI): 0.85 to 0.91]. Sensitivity and specificity of this tool in predicting AKI were 0.85% (95% CI: 0.74% to 0.92%) and 0.79% (95% CI: 0.69% to 0.89%), respectively. The diagnostic odds ratio of RAI was 20.40 (95% CI: 9.62 to 43.25).

Conclusion: The findings of the present meta-analysis showed that RAI is a reliable tool in predicting AKI in children.

关键词:
  • Acute Kidney Injuries
  • Renal Insufficiency
  • Severity of Illness Index
  • Child
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Abbasi A, Mehdipour Rabori P, Farajollahi R, Mohammad Ali K, Ataei N, Yousefifard M, 等. Discriminatory precision of renal angina index in prediction of acute kidney injury in children: a systematic review and meta-analysis. Arch Acad Emerg Med [网际网络]. 2020年3月30日 [见引于 2026年7月7日];8(1):e39. 载于: https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/585
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参考

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Menon S, Goldstein SL, Mottes T, Fei L, Kaddourah A, Terrell T, et al. Urinary biomarker incorporation into the renal angina index early in intensive care unit admission optimizes acute kidney injury prediction in critically ill children: a prospective cohort study. Nephrology dialysis transplantation. 2016;31(4):586-94.

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Basu RK, Zappitelli M, Brunner L, Wang Y, Wong HR, Chawla LS, et al. Derivation and validation of the renal angina index to improve the prediction of acute kidney injury in critically ill children. Kidney international. 2014;85(3):659-67.

Basu RK, Kaddourah A, Goldstein SL, Akcan-Arikan A, Arnold M, Cruz C, et al. Assessment of a renal angina index for prediction of severe acute kidney injury in critically ill children: a multicentre, multinational, prospective observational study. The Lancet Child and Adolescent Health. 2018;2(2):112-20.

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Menon S, Goldstein SL, Mottes T, Fei L, Kaddourah A, Terrell T, et al. Urinary biomarker incorporation into the renal angina index early in intensive care unit admission optimizes acute kidney injury prediction in critically ill children: a prospective cohort study. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2016;31(4):586-94.

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Basu RK, Wang Y, Wong HR, Chawla LS, Wheeler DS, Goldstein SL. Incorporation of biomarkers with the renal angina index for prediction of severe AKI in critically ill children. Clinical journal of the American Society of Nephrology : CJASN. 2014;9(4):654-62.

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