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学术急诊医学档案

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  3. 卷 14 编号 1 (2026): Continuous volume
  4. Case Report

卷 14 编号 1 (2026)

十月 2025

Myocardial Infarction with Non-obstructive Coronary Arteries; Diffuse Large B-Cell Lymphoma Presenting as an Acute Coronary Syndrome

  • Rahul Vilas Deshpande
  • Gregory Milne Aroney
  • Teng Fong Ng
  • Erin Jayne Stirling
  • Alireza Baratloo

学术急诊医学档案, 卷 14 编号 1 (2026), 1 十月 2025 , 第 e54 页
https://doi.org/10.22037/aaem.v14i1.3130 已出版: 2026-09-15

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摘要

A 69-year-old man presented with sudden-onset crushing chest pain, diaphoresis, and syncope with ECG findings prompting treatment as a ST-elevation myocardial infarction (STEMI). Emergency coronary angiography demonstrated no obstructive coronary artery disease. Subsequent investigations including cardiac magnetic resonance imaging (MRI) and positron emission tomography (PET) scan demonstrated an infiltrative mass. Biopsy of a supraclavicular lymph node established a diagnosis of diffuse large B-cell lymphoma (DLBCL) with cardiac involvement. The patient was treated with corticosteroids and immunochemotherapy (DA-R-EPOCH), achieving complete remission on surveillance imaging. This case therefore contributes valuable evidence regarding the varied cardiovascular manifestations of lymphoma and reinforces the importance of maintaining a broad differential diagnosis in patients presenting with features of myocardial infarction with non-obstructive coronary arteries (MINOCA).

关键词:
  • Acute Coronary Syndrome
  • Emergency Medicine
  • Heart Neoplasms
  • Lymphoma, Large B-Cell, Diffuse
  • Magnetic Resonance Imaging
  • MINOCA
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Vilas Deshpande R, Milne Aroney G, Fong Ng T, Jayne Stirling E, Baratloo A. Myocardial Infarction with Non-obstructive Coronary Arteries; Diffuse Large B-Cell Lymphoma Presenting as an Acute Coronary Syndrome. Arch Acad Emerg Med [网际网络]. 2026年9月15日 [见引于 2026年9月27日];14(1):e54. 载于: https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/3130
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参考

1. Sykes R, Doherty D, Mangion K, Morrow A, Berry C. What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries. Interv Cardiol. 2021;16:e10.

2. Tamis-Holland JE, Jneid H, Reynolds HR, Agewall S, Brilakis ES, Brown TM, et al. Contemporary Diagnosis and Manage-ment of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease: A Scientific State-ment From the American Heart Association. Circulation. 2019;139(18):e891-e908.

3. Yildiz M, Ashokprabhu N, Shewale A, Pico M, Henry TD, Quesada O. Myocardial infarction with non-obstructive coro-nary arteries (MINOCA). Front Cardiovasc Med. 2022;9:1032436.

4. Sehn LH, Salles G. Diffuse Large B-Cell Lymphoma. N Engl J Med. 2021;384(9):842-58.

5. Petrich A, Cho SI, Billett H. Primary cardiac lymphoma: an analysis of presentation, treatment, and outcome patterns. Cancer. 2011;117(3):581-9.

6. Miguel CE, Bestetti RB. Primary cardiac lymphoma. Int J Cardiol. 2011;149(3):358-63.

7. Jeudy J, Burke AP, Frazier AA. Cardiac Lymphoma. Radiol Clin North Am. 2016;54(4):689-710.

8. Chuang JY, Chen KT, Lin J, Lim KH, Sung MT. Electrocardi-ographic manifestations and targeted management of cardiac complications in cardiac-involved DLBCL: a retrospective case series. Cardio-oncology. 2025;11(1):118.

9. Mousavi N, Cheezum MK, Aghayev A, Padera R, Vita T, Steigner M, et al. Assessment of Cardiac Masses by Cardiac Magnetic Resonance Imaging: Histological Correlation and Clinical Outcomes. J Am Heart Assoc. 2019;8(1):e007829.

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