The Risk of Venous Thromboembolism Associated with Oral  Contraceptive; the Search Is Still On

Ali Abdalvand

doi:10.22037/aaem.v2i2.27

卷 2 编号 2 (2014)

五月 2014

The Risk of Venous Thromboembolism Associated with Oral Contraceptive; the Search Is Still On

Ali Abdalvand

学术急诊医学档案, 卷 2 编号 2 (2014), 1 五月 2014 , 第 53 页
https://doi.org/10.22037/aaem.v2i2.27 已出版: 2018-11-14

摘要

A few years after coming to the market, the first generation of oral contraceptive pills (OCPs) were linked to significant risk of venous thromboembolism (VTE). This increased risk was blamed on the presence of the estrogen-like compounds in these agents. Therefore, the efforts were initiated to decrease the VTE risk of OCPs by lowering the delivered estrogen content by adding progestins such as levonorgestrel to these products, which led to production of the second generation of OCPs. Thereafter, the third generation of these agents with lower doses of progesterone-like compounds with contraceptive efficacy was released. They contain the new progestins such as Drospirenone, Norgestimate, Desogestrel and Gestodene (1-3).

##submission.howToCite##

Abdalvand A. The Risk of Venous Thromboembolism Associated with Oral Contraceptive; the Search Is Still On. Arch Acad Emerg Med [网际网络]. 2018年11月14日 [见引于 2026年10月17日];2(2):53. 载于: https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/27

参考

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Parkin L, Sharples K, Hernandez RK, Jick SS. Risk of venous thromboembolism in users of oral contraceptives containing drospirenone or levonorgestrel: nested case-control study based on UK General Practice Research Database. BMJ. 2011;342:d2139.

Dinger J, Assmann A, MÃ¶hner S, Do Minh T. Risk of venous thromboembolism and the use of dienogest-and drospire-none-containing oral contraceptives: results from a German case-control study. J Fam Plann Reprod Health Care. 2010;36 (3):123-9.

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学术急诊医学档案

卷 2 编号 2 (2014)

The Risk of Venous Thromboembolism Associated with Oral Contraceptive; the Search Is Still On

摘要

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参考

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