Prevalence of Compartment Syndrome and Disseminated Intravascular Coagulation following Rhabdomyolysis; a Systematic Review and Meta-Analysis

Bardia Danaei; Ali Sharifi; Hamid Mazloom; Iraj Najafi; Mehri Farhang Ranjbar; Saeed Safari

doi:10.22037/aaem.v11i1.2083

卷 11 编号 1 (2023)

十一月 2022

Prevalence of Compartment Syndrome and Disseminated Intravascular Coagulation following Rhabdomyolysis; a Systematic Review and Meta-Analysis

学术急诊医学档案, 卷 11 编号 1 (2023), 15 十一月 2022 , 第 e55 页
https://doi.org/10.22037/aaem.v11i1.2083 已出版: 2023-08-01

摘要

Introduction: Rhabdomyolysis (RM) may cause some complications such as compartment syndrome and disseminated intravascular coagulation (DIC), which can affect its prognosis. This systematic review and meta-analysis aimed to investigate the prevalence of the mentioned complications following RM.

Methods: Medline, Embase, and Scopus databases were searched using keywords related to compartment syndrome, DIC, and rhabdomyolysis with appropriate combination. Cohort and cross-sectional studies that conducted research on the prevalence of compartment syndrome and DIC in patients with RM were included in the present study. The desired data were extracted from the included studies and meta-analysis was conducted on them to calculate pooled prevalence of these complications.

Results: Twenty articles were included in our systematic review. The rate of compartment syndrome reported in these studies ranged from 0 to 30.7%. Our meta-analysis revealed the pooled prevalence of 4% (95% confidence interval (CI): 2.20 to 7.40) for compartment syndrome in these studies. The pooled prevalence of this complication was 7.1% (95% CI: 2.90 to 16.00) among patients with severe RM and 4.4% (95% CI: 1.80 to 10.00) in traumatic RM. The rate of DIC reported in the included studies ranged from 0 to 40.47%. Our meta-analysis showed the pooled prevalence of 8.3% (95% CI: 03.90 to 16.50) for this complication among RM patients.

Conclusion: We reported the rates of compartment syndrome and DIC in RM patients based on rhabdomyolysis etiologies through an epidemiologic systematic review and meta-analysis. The rate of compartment syndrome was slightly higher in patients with severe RM and its rate in patients with traumatic RM was close to the overall rate of compartment syndrome.

关键词:

Rhabdomyolysis
Acute Coronary Syndrome
Blood coagulation disorders
DIC
Disseminated intravascular coagulation
Systematic review
meta-analysis

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Danaei B, Sharifi A, Mazloom H, Najafi I, Farhang Ranjbar M, Safari S. Prevalence of Compartment Syndrome and Disseminated Intravascular Coagulation following Rhabdomyolysis; a Systematic Review and Meta-Analysis. Arch Acad Emerg Med [网际网络]. 2023年8月1日 [见引于 2026年7月7日];11(1):e55. 载于: https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/2083

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学术急诊医学档案

卷 11 编号 1 (2023)

Prevalence of Compartment Syndrome and Disseminated Intravascular Coagulation following Rhabdomyolysis; a Systematic Review and Meta-Analysis

摘要

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