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学术急诊医学档案

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  3. 卷 10 编号 1 (2022): Continuous volume
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卷 10 编号 1 (2022)

一月 2022

Risk Factors of Readmission in COVID-19 Patients; a Retrospective 6-Month Cohort Study

  • Mohammad Haji Aghajani
  • Reza Miri
  • Mohammad Sistanizad
  • Amirmohammad Toloui
  • Arian Madani Neishaboori
  • Asma Pourhoseingholi
  • Ziba Asadpoordezaki
  • Roxana Sadeghi
  • Mahmoud Yousefifard

学术急诊医学档案, 卷 10 编号 1 (2022), 1 一月 2022 , 第 e48 页
https://doi.org/10.22037/aaem.v10i1.1514 已出版: 2022-06-20

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摘要

Introduction: The available literature regarding the rate of readmission of COVID-19 patients after discharge is rather scarce. Thus, the aim in the current study was to evaluate the readmission rate of COVID-19 patients and the components affecting it, including clinical symptoms and relevant laboratory findings.

Methods: In this retrospective cohort study, COVID-19 patients who were discharged from Imam Hossein hospital, Tehran, Iran, were followed for six months. Data regarding their readmission status were collected through phone calls with COVID-19 patients or their relatives, as well as hospital registry systems. Eventually, the relationship between demographic and clinical characteristics and readmission rate was assessed.

Results: 614 patients were entered to the present study (mean age 58.7±27.2 years; 51.5% male). 53 patients were readmitted (8.6%), of which 47 patients (7.6%) had a readmission during the first 30 days after discharge. The reasons for readmission were relapse of COVID-19 symptoms and its pulmonary complications in 40 patients (6.5%), COVID-19 related cardiovascular complications in eight patients (1.3%), and non-COVID-19 related causes in five patients (0.8%). Older age (OR=1.04; 95% CI: 1.01, 1.06; p=0.002) and increased mean arterial pressure during the first admission (OR=1.04; 95% CI: 1.01, 1.08; p=0.022) were found to be independent prognostic factors for the readmission of COVID-19 patients.

Conclusion: Readmission is relatively frequent in COVID-19 patients. Lack of adequate hospital space may be the reason behind the early discharge of COVID-19 patients. Hence, to reduce readmission rate, extra care should be directed towards the discharge of older or hypertensive patients.

关键词:
  • Patient readmission
  • prognosis
  • follow-up studies
  • COVID-19
  • pdf (English)

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Haji Aghajani M, Miri R, Sistanizad M, Toloui A, Madani Neishaboori A, Pourhoseingholi A, 等. Risk Factors of Readmission in COVID-19 Patients; a Retrospective 6-Month Cohort Study. Arch Acad Emerg Med [网际网络]. 2022年6月20日 [见引于 2026年9月7日];10(1):e48. 载于: https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/1514
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参考

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World Health O. Weekly Epidemiological Update 2020 [Available from: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20201005-weekly-epi-update-8.pdf.

Guan W-j, Ni Z-y, Hu Y, Liang W-h, Ou C-q, He J-x, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382(18):1708-20.

MadaniNeishaboori A, Moshrefiaraghi D, Ali KM, Toloui A, Yousefifard M, Hosseini M. Central Nervous System Complications in COVID-19 Patients; a Systematic Review and Meta-Analysis based on Current Evidence. Arch Acad Emerg Med. 2020;8(1):e62.

Guan W-j, Liang W-h, Zhao Y, Liang H-r, Chen Z-s, Li Y-m, et al. Comorbidity and its impact on 1590 patients with Covid-19 in China: A Nationwide Analysis. Eur Respir J. 2020;55(5):2000547.

Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395:1054-62.

Emami A, Javanmardi F, Pirbonyeh N, Akbari A. Prevalence of underlying diseases in hospitalized patients with COVID-19: a systematic review and meta-analysis. Arch Acad Emerg Med. 2020;8(1):e35.

Khateri S, Mohammadi H, Khateri R, Moradi Y. The Prevalence of Underlying Diseases and Comorbidities in COVID-19 Patients; an Updated Systematic Review and Meta-analysis. Arch Acad Emerg Med. 2020;8(1):e72.

Jeon W-H, Seon JY, Park S-Y, Oh I-H. Analysis of Risk Factors on Readmission Cases of COVID-19 in the Republic of Korea: Using Nationwide Health Claims Data. Int J Environ Res Public Health. 2020;17(16):5844.

Parra LM, Cantero M, Morras I, Vallejo A, Diego I, Jimenez-Tejero E, et al. Hospital readmissions of discharged patients with COVID-19. Int J Gen Med. 2020;13:1359–66.

Donnelly JP, Wang XQ, Iwashyna TJ, Prescott HC. Readmission and Death After Initial Hospital Discharge Among Patients With COVID-19 in a Large Multihospital System. JAMA. 2021;325(3):304-6.

Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, et al. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area. JAMA. 2020;323(20):2052-9.

Somani SS, Richter F, Fuster V, De Freitas JK, Naik N, Sigel K, et al. Characterization of patients who return to hospital following discharge from hospitalization for COVID-19. J Gen Intern Med. 2020;35(10):2838-44.

Yeo I, Baek S, Kim J, Elshakh H, Voronina A, Lou MS, et al. Assessment of Thirty-Day Readmission Rate, Timing, Causes, and Predictors after Hospitalization with COVID-19. J Intern Med.290(1):157-65.

Ramzi ZS. Hospital readmissions and post-discharge all-cause mortality in COVID-19 recovered patients; A systematic review and meta-analysis. Am J Emerg Med. 2022;51:267-79.

SeyedAlinaghi S, Afsahi AM, MohsseniPour M, Behnezhad F, Salehi MA, Barzegary A, et al. Late Complications of COVID-19; a Systematic Review of Current Evidence. Arch Acad Emerg Med. 2021;9(1):e14.

Zali A, Gholamzadeh S, Mohammadi G, Looha MA, Akrami F, Zarean E, et al. Baseline Characteristics and Associated Factors of Mortality in COVID-19 Patients; an Analysis of 16000 Cases in Tehran, Iran. Arch Acad Emerg Med. 2020;8(1):e70.

Gholamzadeh S, Mohammadi G, Looha MA, Akrami F, Zarean E, Vafaee R, et al. Baseline Characteristics and Associated Factors of Mortality in COVID-19 Patients; an Analysis of 16000 Cases in Tehran, Iran. Arch Acad Emerg Med. 2020;8(1):e70-e.

Atalla E, Kalligeros M, Giampaolo G, Mylona EK, Shehadeh F, Mylonakis E. Readmissions among Patients with COVID‐19. Int J Clin Pract. 2020;75(3):e13700.

Health NIo. Study Quality Assessment Tools| National Heart, Lung, and Blood Institute (NHLBI) United States: National Institutes of Health; 2014 [Available from: https://www.nhlbi.nih.gov/health-topics/study-quality-assessment-tools.

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