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  3. Vol. 13 No. 1 (2025): Continuous volume
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Vol. 13 No. 1 (2025)

September 2025

Updated Protocol for Stroke Code Management in Prehospital Settings: The Iranian Comprehensive Stroke Code Management Program (ICSCM Phase II)

  • Shayan Alijanpour
  • Fatemeh Bahramnezhad
  • Ashkan Mowla
  • Mahdi Shafiee Sabet
  • Nahid Dehghan Nayeri

Archives of Academic Emergency Medicine, Vol. 13 No. 1 (2025), 6 September 2025 , Page e43
https://doi.org/10.22037/aaemj.v13i1.2633 Published: 2025-04-05

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Abstract

Introduction: Code stroke is a framework to reduce time and improve the quality of care in the prehospital setting. However, increased scene time, delays, and other barriers in the prehospital setting necessitate updating the current protocol. This study aimed to update the Iranian national code stroke protocol for the prehospital setting.

Methods: This study represents the results of the second phase of the Iranian Comprehensive Stroke Code Management Program, a mixed methods study. We used the Caspian scientific 10-step method to update this protocol, which included a literature review, critical appraisal, extraction of recommendations, face-content validity, the Delphi method, RAND method, expert panel, stakeholders, and publishing and printing. We divided the updated protocol into three stages (on scene, ambulance care, and on admission).

Results: Twenty experts (55% nurses; mean age 40.7±9.1 years, experience 15.9±7.9 years) were enrolled. On-Scene focuses on rapid ABC (airway, breathing, circulation) assessment, BEFAST (balance, eyes, face, arm, speech, and time) criteria, blood glucose check, and on-scene time under 5 minutes. Ambulance Care Involving SAMPLER (Symptoms, Allergies, Medications, Past medical history, Last time the patient was seen normally, Events leading up to the emergency medical service call, and Risk factor) history-taking, maintaining oxygen saturation ≥94%, symptom/witness documentation, electrocardiography (ECG) for cardiac-stroke cases, master's degree (MSN)-led transport coordination, and neurology team alerts and in-hospital admission ensuring precise handover, 724 pager alerts, stroke code clocks, computed tomography (CT)-ready team, and protocol updates via joint committees.

Conclusion: The main points were the stroke clock, pager 724, direct delivery to computed tomography scan, administering BEFAST, and reducing scene time. We recommend that each center to enhance the infrastructure and resources for implementation of these updates. In the next phase, we will implement and evaluate this protocol.

Keywords:
  • Stroke
  • Acute Cerebrovascular Accident
  • Stroke Emergency Medical Services
  • Clinical Protocols
  • Emergency medical services
  • pdf

How to Cite

1.
Alijanpour S, Bahramnezhad F, Mowla A, Shafiee Sabet M, Dehghan Nayeri N. Updated Protocol for Stroke Code Management in Prehospital Settings: The Iranian Comprehensive Stroke Code Management Program (ICSCM Phase II). Arch Acad Emerg Med [Internet]. 2025 Apr. 5 [cited 2026 Jul. 7];13(1):e43. Available from: https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/2633
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References

Djalalinia S, Saeedi Moghaddam S, Rezaei N, Rezaei N, Mansouri A, Abdolhamidi E, et al. National and sub-national patterns of mortality from stroke in the Iranian population (1990–2015): Complementary results from the NASBOD study. International Journal of Stroke. 2020;15(2):132-48.

Alijanpour S, Alimohamadi N, Khafri S, Rokni MA, Khorvash F. Caspian nursing process: Impactions on new-onset constipations in admission, discharge, and follow-up of acute stroke patients. J Iranian Journal of Nursing Midwifery Research. 2022;27(6):509-16.

Kolls BJ, Ehrlich ME, Monk L, Shah S, Roettig M, Iversen E, et al. Regionalization of stroke systems of care in the stroke belt states: The IMPROVE stroke care quality improvement program. American Heart Journal. 2024;269:72-83.

National Association of State EMS Officials (NASEMSO). National Model EMS Clinical Guidelines 2022 [Available from: https://nasemso.org/projects/model-ems-clinical-guidelines/.

Poureskandari M, Ala A, Sadeghi-Hokmabadi E, Rahmani F, Amin M, Vahdati SSJEJoEM. Evaluation of Pre-hospital Stroke Diagnosis Agreement with Emergency Diagnosis. 2023;22(3):161-6.

Nazar E, Esmaily H, Yousefi R, Jamali J, Ghandehari K, Hashtarkhani S, et al. A Spatial Variation Analysis of In-Hospital Stroke Mortality Based on Integrated Pre-Hospital and Hospital Data in Mashhad, Iran. 2023;26(6):300.

Asna Ashari Amiri M, Rezai M, Mohammadi F, Vaziri S, Tabibzadeh Dezfooli SA. Accuracy of Prehospital Emergency Service in Activating Acute Stroke Code. Journal of Mazandaran University of Medical Sciences. 2023;33(224):163-9.

Hassankhani H, Soheili A, Vahdati SS, Mozaffari FA, Fraser JF, Gilani N. Treatment delays for patients with acute ischemic stroke in an Iranian emergency department: A retrospective chart review. Annals of emergency medicine. 2019;73(2):118-29.

Sangari A, Akhoundzadeh K, Vahedian M, Sharifipour E. Effect of pre-hospital notification on delays and neurological outcomes in acute ischemic stroke. Australasian emergency care. 2022;25(2):172-5.

Hanifi N, Dinmohammadi M, Ghadimi N. Factors affecting pre-hospital and in-hospital delays at time-to-treatment and complications in stroke: A prospective cohort study. 2020.

Shahjouei S, Bavarsad-Shahripour R, Assarzadegan F, Rikhtegar R, Mehrpour M, Zamani B, et al. Acute management of stroke in Iran: Obstacles and solutions. 2017;16(2):62.

Meza HT, Inda IS, Ponz MS, Ara J, Moreno JM. Impact of a series of measures for optimisation hospital code stroke care on door-to-needle times. Neurologia. 2023;38(3):141-9.

Alijanpour S, Alimohamadi N, Khafri S, Khorvash F. New-onset constipation after stroke: Caspian nursing process projects. Journal of Holistic Nursing Midwifery. 2022;32(1):29-39.

Mousazadeh Y, Nasr A, Alimohammadi N, Isfahani MN, Alijanpour S. Development and domestication of a clinical guideline for pharmacological pain management of trauma patients in prehospital setting. Archives of Trauma Research. 2019;8(2):110-7.

Altman DG, Simera I, Hoey J, Moher D, Schulz K. EQUATOR: reporting guidelines for health research. The Lancet. 2008;371(9619):1149-50.

Karunarathna I, Kusumarathna K, Jayathilaka P, Rathnayake B, Bandara S, Abeykoon M, et al. Understanding Evidence Levels in Evidence-Based Medicine: A Guide for Healthcare Professionals. 2024.

García-Peña C, Pérez-Zepeda MU, Robles-Jiménez LV, Sánchez-García S, Ramírez-Aldana R, Tella-Vega P. Mortality and associated risk factors for older adults admitted to the emergency department: a hospital cohort. BMC Geriatr. 2018;18(1):144.

Hashemi-Domeneh B, Zamani N, Hassanian-Moghaddam H, Rahimi M, Shadnia S, Erfantalab P, et al. A review of aluminium phosphide poisoning and a flowchart to treat it. Arh Hig Rada Toksikol. 2016;67(3):183-93.

Ashcraft S, Wilson SE, Nystrom KV, Dusenbury W, Wira CR, Burrus TM, et al. Care of the patient with acute ischemic stroke (prehospital and acute phase of care): update to the 2009 comprehensive nursing care scientific statement: a scientific statement from the American Heart Association. Stroke. 2021;52(5):e164-e78.

Wiyarta E, Fisher M, Kurniawan M, Hidayat R, Geraldi IP, Khan QA, et al. Global Insights on Prehospital Stroke Care: A Comprehensive Review of Challenges and Solutions in Low-and Middle-Income Countries. Journal of Clinical Medicine. 2024;13(16):4780.

Chen X, Zhao X, Xu F, Guo M, Yang Y, Zhong L, et al. A systematic review and meta-analysis comparing FAST and BEFAST in acute stroke patients. Frontiers in neurology. 2022;12:765069.

Glober NK, Sporer KA, Guluma KZ, Serra JP, Barger JA, Brown JF, et al. Acute stroke: current evidence-based recommendations for prehospital care. Western Journal of Emergency Medicine. 2016;17(2):104.

Mead GE, Sposato LA, Sampaio Silva G, Yperzeele L, Wu S, Kutlubaev M, et al. A systematic review and synthesis of global stroke guidelines on behalf of the World Stroke Organization. International Journal of Stroke. 2023;18(5):499-531.

Fousse M, Grun D, Helwig SA, Walter S, Bekhit A, Wagenpfeil S, et al. Effects of a feedback-demanding stroke clock on acute stroke management: a randomized study. Stroke. 2020;51(10):2895-900.

Ospel JM, Dmytriw AA, Regenhardt RW, Patel AB, Hirsch JA, Kurz M, et al. Recent developments in pre-hospital and in-hospital triage for endovascular stroke treatment. Journal of NeuroInterventional Surgery. 2023;15(11):1065-71.

Boulanger J, Lindsay M, Gubitz G, Smith E, Stotts G, Foley N, et al. Canadian stroke best practice recommendations for acute stroke management: prehospital, emergency department, and acute inpatient stroke care, update 2018. International Journal of Stroke. 2018;13(9):949-84.

Moezzi M, Mozafari J, Barzegari H, Motlagh AH. Knowledge level of pre-hospital emergency staff about acute stroke and indications of code 724. Entomology Applied Science Letters. 2021;8(2-2021):9-15.

Christensen J, Hesstvedt S. The influence of expert groups: a citation analysis. Journal of European Public Policy. 2024;31(5):1259-94.

Chandratre S, Soman A. Preparing for the interviewing process during Coronavirus disease-19 pandemic: Virtual interviewing experiences of applicants and interviewers, a systematic review. PLoS One. 2020;15(12):e0243415.

Zhelev Z WG, Henschke N, Fridhandler J, Yip S. . Prehospital stroke scales as screening tools for early identification of stroke and transient ischemic attack. . Cochrane Database of Systematic Reviews. 2019(4):Art. No.: CD011427. DOI: 10.1002/14651858.CD011427.pub2.

Pandian JD, Kalkonde Y, Sebastian IA, Felix C, Urimubenshi G, Bosch J. Stroke systems of care in low-income and middle-income countries: challenges and opportunities. The Lancet. 2020;396(10260):1443-51.

Yuan J, Li M, Liu Y, Xiong X, Zhu Z, Liu F, et al. Analysis of Time to the Hospital and Ambulance Use Following a Stroke Community Education Intervention in China. JAMA Network Open. 2022;5(5):e2212674-e.

Medical Management of Acute Stroke - Code 724 Babol: Vice- Chancellor’s Office in Treatment Affairs, Babol University of Medical Science; 2025 [Available from: https://darman.mubabol.ac.ir/page/?id=1369.

Malycha J, Bonnici T, Clifton DA, Ludbrook G, Young JD, Watkinson PJ. Patient centred variables with univariate associations with unplanned ICU admission: a systematic review. BMC Med Inform Decis Mak. 2019;19(1):98.

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