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Archives of Academic Emergency Medicine

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  4. Original/Research Article

Vol. 10 No. 1 (2022)

January 2022

Association of CT Scan Parameters with the Risk of Renal Angiomyolipoma Rupture; a Brief Report

  • Razieh Heidari
  • Mostafa Ghadamzadeh
  • Mansour Bahardoust
  • Forugh Khezrian
  • Afrooz Moradkhani
  • Parmida Ghadimi
  • Seyed Morteza Bagheri

Archives of Academic Emergency Medicine, Vol. 10 No. 1 (2022), 1 January 2022 , Page e7
https://doi.org/10.22037/aaem.v10i1.1472 Published: 2022-01-01

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Abstract

Introduction: Rupture of renal angiomyolipoma (AML) is an emergency and life-threatening complication. This study aimed to evaluate the association of computed tomography (CT) scan parameters with the risk of rupture in renal AMLs.

Methods: In this retrospective cross-sectional study, patients who were referred to a referral university hospital with diagnosis of AML, between 2007 and 2019, were included. Patients were divided into ruptured and non-ruptured cases based on surgery and CT scan findings and the baseline characteristics as well as CT scan parameters were compared between the two groups.

Results: 20 AML patients with the mean age of 39.6 ± 12.5 years were included (75% female). The lesion was ruptured in 8 (40%) patients. The mean size of the lesion was ‎97.0 ± 15.9 mm‎‏ in the ruptured and ‏‎72.0 ± 29.4‎‏ in the non‎-‎ruptured AML ‏‎(‎p ‎= ‎‏0.045). The ‎mean fat density based on non-contrast enhanced CT (NCCT) scan (-‎56.1 ± 16.3 ‎vs ‎-‎‎74.9±24.1; ‏p = ‏‎0.018) and contrast enhanced CT (CECT) scan (-‎20.8 ± 16.9 ‎vs ‎-‎‎50.5 ± 31.7; ‏p ‏= ‏‎0.‎016) was significantly higher in the ruptured cases. Total tumor density based on NCCT scan was significantly greater in the ruptured ‎AMLs ‏(‏‎19.6 ± 25.9 ‎‏ vs‎ ‎-22.7±41.6, p=0.033).

Conclusion: It seems that some CT scan parameters such as mean fat density and ‎total tumor density ‏could be used for differentiation between ruptured and non-ruptured AMLs.

Keywords:
  • Angiomyolipoma
  • kidney
  • tomography, X-ray computed
  • neoplasms
  • rupture
  • emergencies
  • pdf

How to Cite

1.
Heidari R, Ghadamzadeh M, Bahardoust M, Khezrian F, Moradkhani A, Ghadimi P, et al. Association of CT Scan Parameters with the Risk of Renal Angiomyolipoma Rupture; a Brief Report. Arch Acad Emerg Med [Internet]. 2022 Jan. 1 [cited 2026 Jul. 7];10(1):e7. Available from: https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/1472
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References

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Bagheri SM, Khajehasani F, Fatemi I, Ayoubpour MR. Tumoral vascular pattern in renal cell carcinoma and fat-poor renal angiomyolipoma as a novel helpful differentiating factor on contrast-enhanced CT scan. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2017;39(10):1010428317733144.

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