Outcomes of Phosphorus-32 Intracavitary Irradiation for Craniopharyngiomas: A Review of The Literature
International Clinical Neuroscience Journal,
Vol. 3 No. 1 (2016),
9 July 2016
,
Page 7-24
https://doi.org/10.22037/icnj.v3i1.12378
Abstract
Purpose: To review on outcomes of Phosphorus-32 (32P) intracavitary irradiation for Craniopharyngiomas.
Methods: A literature review of all full publications in English biomedical journals (1981-2014) was performed. The search strategy included a combination of key words “phosphorus-32”, “craniopharyngioma”, “intracystic treatment”, “brain”, “cyst”, “tumor”, “brachytherapy”, “intracavitary irradiation”, “isotope” in the title and abstract of the manuscripts using the PubMed. The major findings were summarized, with a focus on outcome as visual acuity, complications, cyst volume, and irradiation dose delivered to the cyst wall in Gy. Finally, the future of 32P intracavitary irradiation for Craniopharyngiomas was explored.
Results: A total of 25 citations were identified and screened. In all, 19 citations were eligible for inclusion. The synthesis of the data showed several benefits and adverse events for 32P intracavitary. Overall benefits included improvements in visual, endocrinological, and neurological outcomes, while adverse effects included complications such as III palsy and diabetes insipidus.
Conclusion: In general 32P intracavitary irradiation was found to be a reasonable option in treatment of highly selected patients with newly diagnosed or recurrent cystic craniopharyngioma. This approach can be expected to overcome some limitations introduced by other approaches with a relatively low complication rates.
- Phosphorus-32
- Craniopharyngiomas
- Review
- Outcomes
How to Cite
References
Shapiro K, Till K, Grant DN. Craniopharyngiomas in childhood. A rational approach to treatment. J Neurosurg. 1979 ;50 (5):617-23.
Müller HL. Childhood craniopharyngioma--current concepts in diagnosis, therapy and follow-up. Nat Rev Endocrinol. 2010 ;6(11):609-18.
Shahzadi S, Sharifi G, Andalibi R, Zali A, Ali-Asgari A. Management of cystic craniopharyngiomas with intracavitary irradiation with 32P. Arch Iran Med. 2008 Jan;11(1):30-4.
Müller HL. Craniopharyngioma. Endocr Rev. 2014;35:513-43.
Leksell L, Bactdund EO, Johansson L. Treatment of craniopharyngiomas. Acta Chir Scand 1967; 133(5):345-350.
Lunsford LD, Gumerman L, Levine G. Stereotactic intracavitary irradiation of cystic neoplasms of the brain. Appl Neurophysiol. 1985;48 (1-6):146-50.
Tian Z. Stereotactic intracavitary irradiation of large cystic craniopharyngiomas. J Clin Neurosci. 1997;4 (2):161-2.
Barriger RB, Chang A, Lo SS, Timmerman RD, DesRosiers C, Boaz JC, Fakiris AJ. Phosphorus-32 therapy for cystic craniopharyngiomas. Radiother Oncol. 2011 Feb;98(2):207-12.
Pollock BE, Lunsford LD, Kondziolka D, Levine G, Flickinger JC. Phosphorus-32 intracavitary irradiation of cystic craniopharyngiomas: current technique and long-term results. Int J Radiat Oncol Biol Phys. 1995 Sep 30;33(2):437-46.
Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L, et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst. 2000 Feb 2;92(3):205-16.
Pollack IF, Lunsford LD, Slamovits TL, Gumerman LW, Levine G, Robinson AG. Stereotaxic intracavitary irradiation for cystic craniopharyngiomas. J Neurosurg. 1988 Feb;68(2):227-33.
Kickingereder P, Maarouf M, El Majdoub F, Fuetsch M, Lehrke R, Wirths J, Et al. Intracavitary brachytherapy using stereotactically applied phosphorus-32 colloid for treatment of cystic craniopharyngiomas in 53 patients. J Neurooncol. 2012 Sep;109(2):365-74.
Anderson DR, Trobe JD, Taren JA, Gebarski SS. Visual outcome in cystic craniopharyngiomas treated with intracavitary phosphorus-32. Ophthalmology. 1989 Dec;96(12):1786-92.
Hasegawa T, Kondziolka D, Hadjipanayis CG, Lunsford LD. Management of cystic craniopharyngiomas with phosphorus-32 intracavitary irradiation. Neurosurgery. 2004 Apr;54(4):813-20.
Floyd JR, Cmelak A, Russell P, Weaver KD. Endoscopic, image-guided, transnasal instillation of (32)P for recurrent infrachiasmatic cystic craniopharyngioma. Minim Invasive Neurosurg. 2009 Jun;52(3):137-40.
Einhaus SL, Sanford RA. Craniopharyngiomas. In: Albright AL, Pollack IF, Adelson PD (eds) Principles and practice of pediatric neurosurgery.Thieme, New York,1999. pp 545–562.
Hall WA, Liu H, Truwit CL. Intraoperative MR-guided instillation of phosphorus-32 for cystic craniopharyngiomas: case report. Technol Cancer Res Treat. 2003;2(1):19-24.
Zhao R, Deng J, Liang X, Zeng J, Chen X, Wang J. Treatment of cystic craniopharyngioma with phosphorus-32 intracavitary irradiation. Childs Nerv Syst. 2010 May;26(5):669-74.
Lunsford LD, Pollock BE, Kondziolka DS, Levine G, Flickinger JC. Stereotactic options in the management of craniopharyngioma. Pediatr Neurosurg. 1994;21 Suppl 1:90-7.
Voges J, Sturm V, Lehrke R, Treuer H, Gauss C, Berthold F. Cystic craniopharyngioma: long-term results after intracavitary irradiation with stereotactically applied colloidal beta-emitting radioactive sources. Neurosurgery. 1997 Feb;40(2):263-9; discussion 269-70.
Albright AL, Hadjipanayis CG, Lunsford LD, Kondziolka D, Pollack IF, Adelson PD. Individualized treatment of pediatric craniopharyngiomas. Childs Nerv Syst. 2005 Aug;21(8-9):649-54.
Schefter JK, Allen G, Cmelak AJ, Johnson M, Toms S, Duggan D, et al. The utility of external beam radiation and intracystic 32P radiation in the treatment of craniopharyngiomas. J Neurooncol. 2002 Jan;56(1):69-78.
Taasan V, Shapiro B, Taren JA, Beierwaltes WH, McKeever P, Wahl RL, et al. Phosphorus-32 therapy of cystic Grade IV astrocytomas: technique and preliminary application. J Nucl Med. 1985 Nov;26(11):1335-8.
Kobayashi T, Kageyama N, Ohara K. Internal irradiation for cystic craniopharyngioma. J Neurosurg. 1981;55(6):896-903
Kumar PP, Good RR, Skultety FM, Jones EO, Chu WK. Retreatment of recurrent cystic craniopharyngioma with chromic phosphorus P 32. J Natl Med Assoc. 1986
Jun;78(6):542-3, 547-9.
Winn RH (Ed). Youmans neurological surgery. Aghi MK, McDermott MW, Sneed PK. Berger MS. Interstitial and intracavitary irradiation of brain tumors. Chapter 253. Philadelphia: W.B. Saunders Press; 2011. pp. 2609- 2615.
Elliott RE, Hsieh K, Hochm T, Belitskaya-Levy I, Wisoff J, Wisoff JH. Efficacy and safety of radical resection of primary and recurrent craniopharyngiomas in 86 children. J Neurosurg Pediatr. 2010 Jan;5(1):30-48.
Sands SA, Milner JS, Goldberg J, Mukhi V, Moliterno JA, Maxfield C, et al. Quality of life and behavioral follow-up study of pediatric survivors of craniopharyngioma. J Neurosurg. 2005 Oct;103(4 Suppl):302-11.
Müller HL, Gebhardt U, Teske C, Faldum A, Zwiener I, Warmuth-Metz M, et al. Study Committee of KRANIOPHARYNGEOM 2000. Post-operative hypothalamic lesions and obesity in childhood craniopharyngioma: results of the multinational prospective trial KRANIOPHARYNGEOM 2000 after 3-year follow-up. Eur J Endocrinol. 2011 Jul;165(1):17-24.
Lin LL, El Naqa I, Leonard JR, Park TS, Hollander AS, Michalski JM, et al. Long-term outcome in children treated for craniopharyngioma with and without radiotherapy. J Neurosurg Pediatr. 2008 Feb;1(2):126-30.
Ishida M, Hotta M, Tsukamura A, Taga T, Kato H, Ohta S, et al. Malignant transformation in craniopharyngioma after radiation therapy: a case report and review of the literature. Clin Neuropathol. 2010 Jan-Feb;29(1):2-8.
Aquilina K, Merchant TE, Rodriguez-Galindo C, Ellison DW, Sanford RA, Boop FA. Malignant transformation of irradiated craniopharyngioma in children: report of 2 cases. J Neurosurg Pediatr. 2010 Feb;5(2):155-61.
Kobayashi T, Kida Y, Mori Y, Hasegawa T. Long-term results of gamma knife surgery for the treatment of craniopharyngioma in 98 consecutive cases. J Neurosurg. 2005 Dec;103(6 Suppl):482-8.
Kobayashi T. Long-term results of gamma knife radiosurgery for 100 consecutive cases of craniopharyngioma and a treatment strategy. Prog Neurol Surg 2009; 22: 63-76.
Julow J, Backlund EO, Lányi F, Hajda M, Bálint K, Nyáry I, et al. Long-term results and late complications after intracavitary yttrium-90 colloid irradiation of recurrent cystic craniopharyngiomas. Neurosurgery. 2007
Aug;61(2):288-95; discussion 295-6.
Young HF, Fu YS, Fratkin MJ. Organ culture of craniopharyngioma and its cellular effects induced by colloidal chromic phosphate. J Neuropathol Exp Neurol 1976;35(4):404-412.
Sadeghi M, Moradi S, Shahzadi S, Pourbeigi H. Dosimetry of (32)P radiocolloid for treatment of cystic craniopharyngioma. Appl Radiat Isot. 2007 May;65(5):519-23.
Hechtman CD, Li Z, Mansur DB, Perez CA, Myerson RJ, Simpson JR, et al. Dose distribution outside of a sphere of P-32 chromic phosphorous colloid. Int J Radiat Oncol Biol Phys. 2005 Nov 1;63(3):961-8.
Derrey S, Blond S, Reyns N, Touzet G, Carpentier P, Gauthier H, et al. Management of cystic craniopharyngiomas with stereotactic endocavitary irradiation using colloidal 186Re: a retrospective study of 48 consecutive patients. Neurosurgery. 2008 Dec;63(6):1045-52; discussion 1052-3.
Janicki C, Seuntjens J. Re-evaluation of the dose to the cyst wall in P-32 radiocolloid treatments of cystic brain tumors using the dose-point-kernel and Monte Carlo methods. Med Phys. 2003 ;30(9):2475-81.
Julow J, Lanyi F, Hajda M, Szeifert GT, Balint K, Drasny G, et al. Treatment of cystic craniopharyngiomas with yttrium-90 colloid solution. Neurosurg Focus. 1997 Dec 15;3(6):e6.
Fahlbusch R, Hofmann BM. Surgical management of giant craniopharyngiomas. Acta Neurochir (Wien). 2008;150(12):1213-26.
Cavallo LM, Frank G, Cappabianca P, Solari D, Mazzatenta D, Villa A, et al. The endoscopic endonasal approach for the management of craniopharyngiomas: a series of 103 patients. J Neurosurg. 2014 Jul;121(1):100-13.
- Abstract Viewed: 340 times
- PDF Downloaded: 342 times