INTRODUCTION: The purpose of this study was to evaluate the sealing ability of gray-colored mineral trioxide aggregate (GMTA), white-colored MTA (WMTA), and Resilon as root filling materials. MATERIALS AND METHODS: Sixty-six human maxillary central incisors were used in the present study. In the group A, 20 teeth were filled with GMTA. In the group B, 20 teeth were filled with WMTA and in the group C, 20 teeth were filled with Resilon/Epiphany. Three teeth were used as positive (obturated using the single gutta-percha cone technique without sealer) and three were used as negative (obturated with gutta-percha and AH-26 sealer, coated with two layers of nail varnish) controls. A bacterial leakage model utilizing Enterococcus faecalis was used for evaluation. Leakage was noted when turbidity was observed. RESULTS: Controls behaved as expected. In the group A (GMTA) three samples, in the group B (WMTA) four samples, and in the group C (Resilon/Epiphany), two samples were leaked. There was no statistically significant difference between GMTA and WMTA or GMTA and Resilon. CONCLUSION: In conclusion, sealing ability of GMTA and WMTA was similar to Resilon as orthograde root filling materials.