The value of Computed Tomography in the Diagnostic and Prognostic Prediction of Renal Epithelioid Angiomyolipoma
Urology Journal,
Vol. 20 No. 05 (2023),
23 October 2023
,
Page 337-343
https://doi.org/10.22037/uj.v20i.7675
Abstract
Purpose: This study aimed to assess the importance of computed tomography (CT) imaging in the diagnostic and
prognostic evaluation of renal epithelioid angiomyolipoma (EAML).
Materials and Methods: This study comprised 63 patients diagnosed with renal EAML in the First Affiliated
Hospital of Soochow University during 2010-2021, who met the inclusion criteria. The clinical, pathological, and
therapeutic features were analyzed to determine the optimum diagnostic and therapeutic approaches.
Results: Of the 63 participants, 20 were men and 43 women aged 24-74 years (average, 45.5 years). In 35 and
28 participants, the tumor was located on the left and right sides, respectively. All the patients underwent CT
scanning. Most of the patients (54/63) with EAMLs demonstrated hyperattenuation, one showed isoattenuation,
and eight showed hypoattenuation compared with renal parenchyma on unenhanced CT images. The diameter of
each tumor was 2-25 cm (average, 5.6 cm). All the participants underwent surgical treatment. Of these, 53 were
followed up for 4-128 months (median, 64 months). Among the followed-up patients, one died of the tumor, one
died due to acute severe pancreatitis, and two had an ipsilateral recurrence.
Conclusion: EAML is a relatively rare renal angiomyolipoma depleted in fat. A characteristic of hyperattenuation
on unenhanced CT images in EAML can help distinguish this tumor from clear cell renal cell carcinoma. Surgical
resection is the main treatment. Most EAMLs are benign, and only a few have malignant potential. However,
post-surgery recurrence and metastasis may occur, especially in elderly patients, and thus close follow-up is recommended.
- epithelioid angiomyolipoma; EAML; computed tomography; renal neoplasm; fat-poor AML
How to Cite
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