ISSN: 2383-1871
Summer
Vol. 1 No. 1 (2014)
Ankylosing Spondylitis associated with intracranial aneurysms: report of 2 cases
International Clinical Neuroscience Journal,
Vol. 1 No. 1 (2014),
,
Page 35-38
https://doi.org/10.22037/icnj.v1i1.6694
Abstract
ABSTRACT
Cerebral aneurysms are the major cause of subarachnoid hemorrhage. Common ascribed etiologies are
hemodynamic factors such as atherosclerosis, hypertension, infection, trauma, polycyctic kidney disease, connective tissue disorders like Ehlers-Danlos disease, Marfan syndrome, and familial predisposition. However, its association with ankylosing spondylitis (AS) is not clear. Here, we report 2 patients with AS who presented with subarachnoid hemorrhage which was finally confirmed to be due to cerebral aneurysms, one in posterior communicating artery and the other in basilar artery tip). The patients had no history of hypertension or any other disease. Our data may not strongly suggest that vascular changes due to AS are etiological factors for developing intracranial aneurysm, but this report may show the possibility for existence of an association between these diseases, which has to be confirmed by more genetic and pathologic studies.
- ankylosing spondylitis
- etiology
- intracranial aneurysm
How to Cite
References
Rinkel GJ. Natural history, epidemiology and screening of unruptured intracranial aneurysms. J Neuroradiol.
;35(2):99-103.
Vlak MHM, Algra A, Brandenburg R, Rinkel GJE. Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis. Lancet Neurol. 2011;10(7):626–636.
Choi JY, Sohn JT, Sung HJ, Shin IW, Ok SH, Lee HK, et al. Anesthetic management for the endoscopic sinus surgery of a patient with coexisting severe cervical spine ankylosing spondylitis and unruptured cerebral aneurysm, A case report. Korean J Anesthesiol. 2009;57(2):264-267.
Santiago-Sim T, Kim DH. Pathobiology of Intracranial
Aneurysms. In: Winn RH, editor. Youmans neurological surgery, sixth edition: Elsevier Saunders. 2011;3747-3755.
Miller DV, Maleszewski JJ. The pathology of large-vessel vasculitides. Clin Exp Rheumatol.2011 ;29(1 Suppl 64):S92-
Takagi H, Mori Y, Umeda Y, Fukumoto Y, Kato Y, Shimokawa K, Hirose H. Abdominal aortic aneurysm with arteritis in ankylosing spondylitis. J Vasc Surg.
;38(3):613-616.
- Abstract Viewed: 453 times
- PDF Downloaded: 769 times