Motor Task Processing After Constraint- Induced Movement Therapy in Children With Cerebral Palsy: A Case Series
International Clinical Neuroscience Journal,
Vol. 8 No. 1 (2021),
30 December 2020
Constraint-induced movement therapy (CIMT) has shown positive results in children with hemiplegic cerebral palsy (CP). However, studies on neural basis of such functional gains are limited. This study reports the event-related potential (ERP) changes in two children with hemiplegic CP after receiving CIMT for three weeks. Both cases were nine years old, had a diagnosis of left hemiplegic CP, had normal intelligence, and were able to extend the wrist at least 20° and the metacarpophalangeal joint at least 10° from full flexion. Before and after the three-week intervention, the children participated in ERP sessions with a choice reaction task to capture the changes in neural mechanism after intervention. Both children exhibited improvement in reaction time (RT) in both hand tasks after the intervention. The improvement was larger in the affected hand than the unaffected hand. Improved accuracy rate (AC) and shortened P300 latencies in the affected hand were also demonstrated in both cases. Topographical maps showed that in centro-parietal regions, patterns shifted from central and left-lateralized to more central and right-lateralized. CMIT was a useful method in improving upper limb function in our cases.
- Constraint-induced movement therapy
- Cerebral palsy
- Upper limb functional regain
- Event-related potentials
How to Cite
Taub E, Morris DM. Constraint-induced movement therapy to enhance recovery after stroke. Current Atherosclerosis Reports. 2001;3:279-86.
Lang KC, Thompson PA, Wolf SL. The EXCITE Trial: reacquiring upper-extremity task performance with early versus late delivery of constraint therapy. Neurorehabilitation and Neural Repair. 2013;27:654-63.
Wu CY, Chen CL, Tang SF, Lin KC, Huang YY. Kinematic and Clinical Analyses of Upper-Extremity Movements After Constraint-Induced Movement Therapy in Patients With Stroke: A Randomized Controlled Trial. Archives of Physical Medicine & Rehabilitation. 2007;88:964-70.
Senesac C, Helsel PV, Breton J. Modified Constraint Induced Movement Therapy for Child With Hemiplegia. Pediatric Physical Therapy. 2006;18(1):104.
Gordon AM, Charles J, Wolf SL. Efficacy of constraint-induced movement therapy on involved upper-extremity use in children with hemiplegic cerebral palsy is not age-dependent. Pediatrics. 2006;117(3):e363-e73.
Bowman MH, Mark VW, Taub E. Constraint-Induced Movement Therapy for Restoration of Upper-Limb Function: Introduction. International Handbook of Occupational Therapy Interventions: Springer; 2015. p. 573-85.
Szaflarski JP, Page SJ, Kissela BM, Lee J-H, Levine P, Strakowski SM. Cortical reorganization following modified constraint-induced movement therapy: a study of 4 patients with chronic stroke. Archives of physical medicine and rehabilitation. 2006;87(8):1052-8.
Jünger C, Linder M, Walther M, Berweck S, Mall V, Staudt M. Cortical neuromodulation by constraint induced therapy in congenital hemiparesis–an fMRI study. Clinical Neurophysiology. 2007;118(4):e51-e2.
Sutcliffe TL, Gaetz WC, Logan WJ, Cheyne DO, Fehlings DL. Cortical reorganization after modified constraint induced movement therapy in pediatric hemiplegic cerebral palsy. Journal of Child Neurology. 2007;22:1281-7.
Maitre NL, et al. Feasibility of event-related potential methodology to evaluate changes in cortical processing after rehabilitation in children with cerebral palsy: a pilot study. Journal of Clinical And Experimental Neuropsychology. 2014;36:669-79.
van Dinteren R, Arns M, Jongsma ML, Kessels RP. P300 development across the lifespan: a systematic review and meta-analysis. PloS one. 2014;9(2):e87347.
Abd El-Kafy EM, Elshemy SA, Alghamdi MS. Effect of constraint-induced therapy on upper limb functions: A randomized control trial. Scandinavian journal of occupational therapy. 2014;21(1):11-23.
Hirata K, Katayama S, Yamazaki K, Fujikane M, Katayama K. Electric field distribution of event-related potentials in stroke patients. Brain topography. 1996;8(3):279-84.
Lew HL, Gray M, Poole JH. Simultaneous measurement of perceptual and motor cortical potentials: implications for assessing information processing in traumatic brain injury. American Journal of Physical Medicine & Rehabilitation. 2009;88(1):1-6.
Chung JW, Ofori E, Misra G, Hess CW, Vaillancourt DE. Beta-band activity and connectivity in sensorimotor and parietal cortex are important for accurate motor performance. NeuroImage. 2017;144(Part A):164-73.
- Abstract Viewed: 235 times
- PDF Downloaded: 214 times