International Clinical Neuroscience Journal

Vol. 4 No. 4 (2017)

Comparison of the homodynamic effects of Nesdonal and Propofol in patients under electroconvulsive therapy

International Clinical Neuroscience Journal, Vol. 4 No. 4 (2017), 8 October 2017 , Page 140-142

Abstract

Background: General anesthesia is a safe method for induction of electroconvulsive therapy (ECT) in patients suffering from psychiatric disorders. We aimed to compare the hemodynamic effects of Nesdonal and propofol as induction agents for ECT.
Methods: This semi-experimental study was performed on 84 patients with confirmed diagnosis of psychiatric disorders, who underwent ECT at Shohada Tajrish hospital in 2016. After randomization, each patient either received Nesdonal or propofol for induction of anesthesia. Hemodynamic changes of mentioned anesthetic agents were recorded and evaluated during ECT, including systolic and diastolic blood pressure, heart rate, seizure duration related to the procedure and recovery from sleep. Statistical analysis was performed using Student t test and Friedman test.
Results: There were 50 men and 34 women among included patients. The mean and standard deviation (SD) of age of patients in Nesdonal group in female and male were 40.5 ± 13.4 years and 30.2 ± 13.5 years, respectively. Data for propofol group was 36.5 ± 20.9 years and 25.7 ± 7.7 years for female and male patients, respectively. Nesdonal offered a superior hemodynamic stability during the procedure, and seizure duration has decreased with Nesdonal compared with propofol. However, patients who underwent propofol for their anesthesia recover faster from sleep, while systolic and diastolic blood pressure of this group were higher than Nesdonal group (P < 0.0001).
Conclusion: Considering better hemodynamic stability, it seems that Nesdonal is better than propofol for induction in ECT.

Keywords:
  • Electroconvulsive therapy
  • Anesthesia
  • Nesdonal
  • Propofol

How to Cite

1.
Seddighi A, Nikouei A, Seddighi AS. Comparison of the homodynamic effects of Nesdonal and Propofol in patients under electroconvulsive therapy. Int Clin Neurosci J [Internet]. 2017 Oct. 8 [cited 2023 Dec. 2];4(4):140-2. Available from: https://journals.sbmu.ac.ir/neuroscience/article/view/19306

References

Weiner RD, Falcone G. Electroconvulsive Therapy: How Effective Is It? J Am Psychiatr Nurses Assoc. 2011;17(3):217- 8. doi: 10.1177/1078390311408603.

Thompson JW, Weiner RD, Myers CP. Use of ECT in the United States in 1975, 1980, and 1986. Am J Psychiatry. 1994;151(11):1657-61. doi: 10.1176/ajp.151.11.1657.

Ding Z, White PF. Anesthesia for electroconvulsive therapy. Anesth Analg. 2002;94(5):1351-64. doi: 10.1097/00000539- 200205000-00057.

Lopez-Gomez D, Sanchez-Corral MA, Cobo JV, Jara F, Esplugas E. [Myocardial infarction after electroconvulsive therapy]. Rev Esp Cardiol. 1999;52(7):536.

Weisberg LA, Elliott D, Mielke D. Intracerebral hemorrhage following electroconvulsive therapy. Neurology. 1991;41(11):1849.

Nomoto K, Suzuki T, Serada K, Oe K, Yoshida T, Yamada S. Effects of landiolol on hemodynamic response and seizure duration during electroconvulsive therapy. J Anesth. 2006;20(3):183-7. doi: 10.1007/s00540-006-0401-1.

Ghaziuddin N, Dumas S, Hodges E. Use of continuation or maintenance electroconvulsive therapy in adolescents with severe treatment-resistant depression. J ect. 2011;27(2):168- 74. doi: 10.1097/YCT.0b013e3181f665e4.

American Psychiatric Association. The practice of electroconvulsive therapy: recommendations for treatment, training, and privileging (A task force report of the American Psychiatric Association). Washington: American Psychiatric; 2008.

Dew RE, Kimball JN, Rosenquist PB, McCall WV. Seizure length and clinical outcome in electroconvulsive therapy using methohexital or thiopental. J ect. 2005;21(1):16-8.

Seddighi A, Seddighi AS, Nikouei A, Ashrafi F, Nohesara S. Psychological aspects in brain tumor patients: A prospective study. Hell J Nucl Med. 2015;18 Suppl 1:63-7.

Bauer J, Hageman I, Dam H, Baez A, Bolwig T, Roed J, et al. Comparison of propofol and thiopental as anesthetic agents for electroconvulsive therapy: a randomized, blinded comparison of seizure duration, stimulus charge, clinical effect, and cognitive side effects. J ect. 2009;25(2):85-90. doi: 10.1097/YCT.0b013e31818a0203.

Villalonga A, Bernardo M, Gomar C, Fita G, Escobar R, Pacheco M. Cardiovascular Response and Anesthetic Recovery in Electroconvulsive Therapy with Propofol or Thiopental. Convuls Ther. 1993;9(2):108-11.

Walder B, Seeck M, Tramer MR. Propofol [correction of propfol] versus methohexital for electroconvulsive therapy: a meta-analysis. J Neurosurg Anesthesiol. 2001;13(2):93-8.

Zaidi NA, Khan FA. Comparison of thiopentone sodium and propofol for electro convulsive therapy (ECT). J Pak Med Assoc. 2000;50(2):60-3.

Swartz CM. Propofol Anesthesia in ECT. J ect. 1992;8(4):262- 6.

Harti A, Hmamouchi B, Idali H, Barrou L. [Anesthesia for electroconvulsive therapy: propofol versus thiopental]. Encephale. 2001;27(3):217-21.

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