Effects of Maternal Coagulation disorder on Birth Weight and Post-Natal Non-Coagulation Problems of Neonates
Archives of Medical Laboratory Sciences,
Vol. 5 No. 2 (2019),
20 March 2019
,
Page 36-44
https://doi.org/10.22037/amls.v5i2.31180
Abstract
Background: To evaluate the birth weight and post-natal non-coagulation problems of infants of mothers with coagulopathies versus normal mothers. Materials and Methods: In a retrospective cohort study, 100 women with coagulation problems attended the Iranian Haemophilia Comprehensive Care Center, and 200 normal women attending two health centers in Tehran and Karaj, with a history of at least one pregnancy were studied. A questionnaire about mothers’ and neonates’ condition was filled out by an interview, and the data were analyzed using SPSS software, version 16. Results: Using linear regression, the maternal coagulation problem had a negative effect on birth weight (p<0.001, β= -0.31). The prevalence of early and prolonged jaundice in newborns of mothers with coagulopathy was higher than that in newborns of normal mothers (12% vs. 2%, and 7% vs. 3%, respectively), the difference between the two groups in terms of incidence of early jaundice was statistically significant (chi square-p<0.001). The frequency of using phototherapy and blood exchange for treating neonatal jaundice, in neonates of mothers with coagulopathy was higher than in neonates of normal mothers (31% vs. 21% and 8% vs. 21%, respectively) (p<0.001). Furthermore, the duration of hospitalization, hospitalization in NICU, and re-hospitalization during the first month of life in neonates of mothers with coagulation problems was higher than in neonates of normal mothers (p<0.001). Conclusion: Considering the high prevalence of neonatal problems in newborns of mothers with coagulation problems and their lower birth weight, further care measures should be provided for them.
- Coagulation disorder
- Birth weight
- Neonatal problems
- Neonatal jaundice
How to Cite
References
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