To Reduce the Effects of Experimental Aflatoxicosis in Broiler Chicks Using Specific Egg Yolk Immunoglobulin (IgY)
Archives of Medical Laboratory Sciences,
Vol. 4 No. 1 (2018),
2 March 2019
https://doi.org/10.22037/amls.v4i1.23058
Abstract
Background: This experiment was conducted to evaluate the effects of the specific egg yolk immunoglobulin (IgY) on reducing the defects of experimental aflatoxicosis in broilers.
Materials and Methods: In a completely randomized design, a total of 128 Ross 308 broiler chicks were used in 4 treatments, 4 replicates and 8 observations (chicks) for 42 days. Treatments were: 1) control; 2) diet containing 1 ppm aflatoxin B1; 3) diet contaminated with 1 ppm aflatoxin B1 + 0.75 % of egg yolk containing IgY; 4) diet contaminated with 1 ppm aflatoxin B1 + 1.5 % of egg yolk containing IgY.
Results: The results showed that the use of aflatoxin containing diet significantly increased the feed conversion ratio, serum cholesterol concentration, serum gamma-glutamyl transferase (GGT), and aspartate aminotransferase (AST). Also, experimental aflatoxicosis resulted in reduced feed intake, weight gain, serum total protein and albumin concentrations (p<0.05); as well as the liver histopathologic lesions. IgY containing egg yolk (0.75% and 1.5%) added to the contaminated ration improved feed intake, weight gain and feed conversion ratio compared to treatment 2 (p<0.05). Compared to treatment 2, serum cholesterol concentration decreased while total protein concentration increased in treatments 3 and 4 (p<0.05). Liver tissue was approximately normal with mild effects on hepatocytes and mild cytoplasmic changes in chicks receiving treatments 3 and 4.
Conclusion: It can be concluded that specific IgY is effective in reducing the defects of experimental aflatoxicosis as well as improving performance in broilers.
- Aflatoxin B1
- specific immunoglobulin
- weight gain
- feed conversion ratio
How to Cite
References
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