Evaluation of the Clinical and Laboratory Status of Pregnant Women with COVID-19
Advances in Nursing & Midwifery,
Vol. 31 No. 4 (2022),
15 October 2022
,
Page 25-29
https://doi.org/10.22037/anm.v31i4.39985
Abstract
Abstract
Introduction: The prevalence of the COVID-19 virus has been very high, so that in a short period of time, due to its contagiousness, it has infected a large number of people around the world. Pregnant women are more sensitive to infectious diseases than the general population and are especially at risk of respiratory diseases and severe pneumonia. Considering the importance of mother and fetus management, assessment and management of pregnant women infected with COVID-19, the present study was conducted with the aim of investigating the clinical and laboratory status of pregnant women infected with SARS‐CoV‐2 referring to Imam Hassan and Bentolhoda hospital in Bojnurd.
Methods: In this cross-sectional study, pregnant women with COVID-19 referred to Imam Hassan and Bentolhoda Hospital in Bojnurd between March 2020 and the beginning of Desember 2021 were studied. In order to collect information, an information form containing demographic and obstetric characteristics, evaluation of symptoms (fever, cough, abdominal pain, bloody secretions, rupture of fetal membranes in term pregnancy, chest tightness, asthma, fatigue, loss of appetite, headache, nausea and vomiting), laboratory status and outcomes pregnancy and childbirth was used. Statistical analysis was done with SPSS 24 software.
Results: The age range of the studied women was 15-48 years and the average gestational age was 26.21±9.4 weeks. The type of delivery in 46.2% was normal vaginal delivery, 53.8% was cesarean section. LBW, admission to NICU, need for resuscitation, meconium-stained AF were 5.71%, 4.76%, 3.80%, 0.95%, respectively. The average number of referrals to the hospital due to COVID-19 in the studied women was 1.6 ± 1.1 times, the average number of days in the hospital was 5.1 ± 3.1 days, and the average number of days in the intensive care unit was 4.08±2.1 days. The most common clinical symptoms in the studied women were related to cough (76.19), dyspnea (72.38), fever (56.19), and myalgia (33.33).
Conclusions: Based on the results obtained from this study, clinical symptoms and laboratory results in pregnant women with COVID-19 are similar to infected adults. Common symptoms of COVID-19 disease in pregnant women included fever, cough, and myalgia.
- COVID 19
- Pregnant Women
- Neonates
- SARS-CoV-2 Infections
How to Cite
References
Organization WH. Novel Coronavirus (2019-nCoV) Situation report-9, 29 January 2020. Geneva, Switzerland.2020.
Jafari M, Pormohammad A, Sheikh Neshin SA, Ghorbani S, Bose D, Alimohammadi S, et al. Clinical characteristics and outcomes of pregnant women with COVID-19 and comparison with control patients: A systematic review and meta-analysis. Rev Med Virol. 2021;31(5):1-16. doi: 10.1002/rmv.2208 pmid: 33387448
Schwartz DA, Graham AL. Potential Maternal and Infant Outcomes from (Wuhan) Coronavirus 2019-nCoV Infecting Pregnant Women: Lessons from SARS, MERS, and Other Human Coronavirus Infections. Viruses. 2020;12(2). doi: 10.3390/v12020194 pmid: 32050635
Jamieson DJ, Theiler RN, Rasmussen SA. Emerging infections and pregnancy. Emerg Infect Dis. 2006;12(11):1638-43. doi: 10.3201/eid1211.060152 pmid: 17283611
Liu H, Wang LL, Zhao SJ, Kwak-Kim J, Mor G, Liao AH. Why are pregnant women susceptible to COVID-19? An immunological viewpoint. J Reprod Immunol. 2020;139:103122. doi: 10.1016/j.jri.2020.103122 pmid: 32244166
Investigators AI, Australasian Maternity Outcomes Surveillance S. Critical illness due to 2009 A/H1N1 influenza in pregnant and postpartum women: population based cohort study. BMJ. 2010;340:c1279. doi: 10.1136/bmj.c1279 pmid: 20299694
Rasmussen SA, Jamieson DJ, Bresee JS. Pandemic influenza and pregnant women. Emerg Infect Dis. 2008;14(1):95-100. doi: 10.3201/eid1401.070667 pmid: 18258087
Alserehi H, Wali G, Alshukairi A, Alraddadi B. Impact of Middle East Respiratory Syndrome coronavirus (MERS-CoV) on pregnancy and perinatal outcome. BMC Infect Dis. 2016;16:105. doi: 10.1186/s12879-016-1437-y pmid: 26936356
Wong SF, Chow KM, Leung TN, Ng WF, Ng TK, Shek CC, et al. Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome. Am J Obstet Gynecol. 2004;191(1):292-7. doi: 10.1016/j.ajog.2003.11.019 pmid: 15295381
Wong SF, Chow KM, de Swiet M. Severe Acute Respiratory Syndrome and pregnancy. BJOG. 2003;110(7):641-2. doi: 10.1046/j.1471-0528.2003.03008.x pmid: 12842052
Reid A. The effects of the 1918-1919 influenza pandemic on infant and child health in Derbyshire. Med Hist. 2005;49(1):29-54. doi: 10.1017/s0025727300008279 pmid: 15730129
Gottfreðsson M. Spænska veikin á Íslandi 1918: lærdómur í læknisfræði og sögu.2008.
Jamieson DJ, Honein MA, Rasmussen SA, Williams JL, Swerdlow DL, Biggerstaff MS, et al. H1N1 2009 influenza virus infection during pregnancy in the USA. Lancet. 2009;374(9688):451-8. doi: 10.1016/S0140-6736(09)61304-0 pmid: 19643469
Arakaki T, Hasegawa J, Sekizawa A, Ikeda T, Ishiwata I, Kinoshita K. Clinical characteristics of pregnant women with COVID-19 in Japan: a nationwide questionnaire survey.2021.
Esmailpour Estarkhi R, Borghei NS, Mehrbakhsh Z, Rahimian S. Clinical signs and maternal and neonatal outcomes of pregnant women with Covid-19 hospitalized in the first and second wave of coronavirus in Golestan province. Iran J Obstetric Gynecol Infertilit. 2022;25(7):59-69.
Fayazi M, Rahmani R, Rahmani Bilandi R. Clinical manifestations, maternal, fetal and neonatal outcomes in pregnant women with COVID- 19: A systematic review. Iran J Obstetric Gynecol Infertilit. 2021;24(7):108-19.
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5 pmid: 31986264
Wu W, Wang A, Liu M. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5 pmid: 31986264
Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020;395(10226):809-15. doi: 10.1016/S0140-6736(20)30360-3 pmid: 32151335
Liu D, Li L, Wu X, Zheng D, Wang J, Yang L, et al. Pregnancy and Perinatal Outcomes of Women With Coronavirus Disease (COVID-19) Pneumonia: A Preliminary Analysis. AJR Am J Roentgenol. 2020;215(1):127-32. doi: 10.2214/AJR.20.23072 pmid: 32186894
Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med. 2020;382(8):727-33. doi: 10.1056/NEJMoa2001017 pmid: 31978945
Yu N, Li W, Kang Q, Xiong Z, Wang S, Lin X, et al. Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study. Lancet Infect Dis. 2020;20(5):559-64. doi: 10.1016/S1473-3099(20)30176-6 pmid: 32220284
Akbarzadeh H, Saadati Rad MT, Ebrahimi M, Sina S, Ghabimi M. Coronavirus disease 2019 (covid-19), perinatal and neonatal outcomes: A systematic review study. Nurs Midwife J. 2021;18(10):785-94.
Liu H, Liu F, Li J, Zhang T, Wang D, Lan W. Clinical and CT imaging features of the COVID-19 pneumonia: Focus on pregnant women and children. J Infect. 2020;80(5):e7-e13. doi: 10.1016/j.jinf.2020.03.007 pmid: 32171865
Wang X, Zhou Z, Zhang J, Zhu F, Tang Y, Shen X. A Case of 2019 Novel Coronavirus in a Pregnant Woman With Preterm Delivery. Clin Infect Dis. 2020;71(15):844-6. doi: 10.1093/cid/ciaa200 pmid: 32119083
Liu W, Wang Q, Zhang Q, Chen L, Chen J, Zhang B. Coronavirus disease 2019 (COVID-19) during pregnancy: a case series.2020.
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