Meningioma - a Cause of Sudden Death
International Journal of Medical Toxicology and Forensic Medicine,
Vol. 6 No. 1(Winter) (2016),
12 February 2016
Background: Sudden unexpected death of an apparently healthy individual is an expected event in the life of a forensic expert. Neurological causes account for only 15% of all sudden deaths of which deaths from an undiagnosed primary intracranial neoplasm is exceptionally rare. Meningioma is a common intracranial tumor and it is rarely associated with sudden, unexpected deaths.
Case Report: We report one such case of sudden death in a 32-year old male with an olfactory meningioma without any prior history of neurological symptoms raising queries regarding the cause of death.
Conclusion: This case illustrates the possibility of meningioma remaining silent till middle age and can present with sudden onset of seizures which may lead to fatality.
- Sudden Death
- Intracranial Tumor
How to Cite
Huh GY, Hoon-Kim K, Yong-Woo A, Gam J, Seong M, Sang-Yong L. Sudden Death due to Undiagnosed Intracranial Meningioma: A Case Report. The Korean Journal of Legal Medicine 2008;32:150-2.
DiMaio SM, DiMaio VJM, Kirkpatrick JB. Sudden, unexpected deaths due to primary intracranial neoplasms. Am J Forensic Med Pathol. 1980;1:29-45.
Matschke J, Tsokos M. Sudden unexpected death due to undiagnosed glioblastoma: report of three cases and review of the literature. Int J Legal Med. 2005;119:280-4.
Vougiouklakis T, Mitselou A, Agnantis NJ. Sudden death due to primary intracranial neoplasms. A forensic autopsy study. Anticancer Res. 2006;26:2463-6.
Ironside JW, Moss TH, Louis DN, Lowe JS, Weller RO, Diagnostic pathology of nervous system tumours. London: Churchill Livingstone. 2004;8-10.
Poon TP, Solis OG. Sudden death due to massive intraventricular hemorrhage into an unsuspected ependymoma. Surg Neurol. 1985;24:63-6.
Opeskin K, Ruszkiewicz A, Anderson RM. Sudden death due to undiagnosed medullary-pontine astrocytoma. Am J Forensic Med Pathol. 1995;16:168-71.
Buttner A, Winkler PA, Eisenmenger W, et al. Colloid cysts of the third ventricle with fatal outcome: a case report of two cases and review of the literature. Int J Legal Med. 1997;110:260-6.
Abu Al Ragheb SY, Koussous KJ, Amr SS. Intracranial neoplasms associated with sudden death: a report of seven cases and a review of the literature. Med Sci Law. 1986;26:270-2.
Buttner A, Gall C, Mall G, et al. Unexpected death in persons with symptomatic epilepsy due to glial brain tumors: a report of two cases and review of the literature. Forensic Sci Int. 1999;100:127-36.
Jason R, Maciej M, Marc C. Chamberlain. Intracranial meningiomas: an overview of diagnosis and treatment. Neurosurgical Focus. 2007;23(4):E1.
Yekeler E, Dursun M, Yılmazbayhan D, Tunacı A. Multiple pulmonary metastases from intracranial meningioma: MR imaging findings. Diagn Interv Radiol. 2005;11:28-30.
Enam SA, Abdulrauf S, Mehta B, Malik GM, Mahmood A. Metastasis in meningioma. Acta Neurochir (Wien). 1996;138:1172-8.
Kovoor JM, Jayakumar PN, Srikanth SG, Indira B, Devi MG. Solitary pulmonary metastasis from intracranial meningiothelial meningioma. Australas Radiol. 2002;46:65-8.
Lee BW, Seo JS. Meningioma presenting as cerebral infarct. Kor J Leg Med. 2001;25:53-7.
Ohaegbulam SC. Sudden death from an asymptomatic sphenoid ridge meningioma. J Neurol. 1977;215:291-4.
Helle TL, Conley FK. Haemorrhage associated with meningioma: a case report and review of the literature. J Neurol Neurosurg Psychiatry. 1980;43:725-9.
Hentschel SJ, Demonte F. Olfactory groove meningiomas. Neurosurg Focus. 2003;14:e4.
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