Helium Inhalation Suicide: Hypoxic Asphyxia and Gas Embolism as Dual Mechanisms of Death: A Case Report
International Journal of Medical Toxicology and Forensic Medicine,
Vol. 16 (2026),
1 Dey 2026
,
Page 1-5
https://doi.org/10.22037/ijmtfm.v16.52075
Abstract
Background: Helium is an inert gas without inherent toxic properties, which explains its widespread use in both industrial and medical settings. However, despite its chemical inertness, inhalation of helium can cause severe oxygen displacement within the respiratory system, leading to tissue hypoxia and potentially fatal outcomes.
Case Presentation: Cases of helium intoxication pose particular clinical and forensic difficulties because toxicological examinations may not always produce positive findings. Death associated with helium exposure is primarily caused by hypoxia resulting from the mechanical replacement of oxygen during breathing.
Conclusion: Due to the largely non-specific morphological findings observed at autopsy, establishing the cause and manner of death requires a multidisciplinary approach that integrates scene investigation, forensic pathology, toxicology, and criminalistic analysis.
- Helium inhalation, Suicide, Hypoxic asphyxia, Gas embolism
How to Cite
References
[1] Varlet V, Iwersen‑Bergmann S, Alexandre M, Cordes O, Wunder C, Holz F, et al. Helium poisoning: new procedure for sampling and analysis. Int J Legal Med. 2019;133(6):1809‑18. [DOI: 10.1007/s00414-019-02014-3]
[2] Berganza CJ, Zhang JH. The role of helium gas in medicine. Med Gas Res. 2013;3(1):18. [DOI: 10.1186/2045-9912-3-18]
[3] Smędra A, Łabętowicz P, Wochna K, Berent J. Helium suicide – a suffocation or a barotrauma? J Forensic Leg Med. 2020;76:102065. [DOI: 10.1016/j.jflm.2020.102065]
[4] Malbranque S, Mauillon D, Turcant A, Rouge‑Maillart C, Mangin P, Varlet V. Quantification of fatal helium exposure following self‑administration. Int J Legal Med. 2016;130(6):1535‑9. [DOI: 10.1007/s00414-016-1364-x]
[5] Borowska‑Solonynko A, Dąbkowska A. Gas embolism as a potential cause of death by helium poisoning: postmortem computed tomography changes in two cases of suicidal helium inhalation. Leg Med (Tokyo). 2018;31:59‑65. [DOI: 10.1016/j.legalmed.2018.01.001]
[6] Forrester MB. Helium inhalation injuries managed at emergency departments. Clin Toxicol (Phila). 2020. [DOI: 10.1080/15563650.2020.1776871]
[7] Carfora A, Petrella R, Ambrosio G, Mascolo P, Liguori B, Juhnke C, et al. Helium suicide, a rapid and painless asphyxia: toxicological findings. Toxics. 2022;10(8):424. [DOI: 10.3390/toxics10080424]
[8] Wiergowski M, Kaliszan M, Sumińska‑Ziemann B, Gos T, Jankowski Z. Helium detection in the lungs in case of suicide by helium inhalation: case report and literature review. Rom J Leg Med. 2014;22:153‑6. [DOI: 10.4323/rjlm.2014.153]
[9] Nowak K, Szpot P, Zawadzki M. Suicidal deaths due to helium inhalation. Forensic Toxicol. 2019;37:273‑87. [DOI: 10.1007/s11419-019-00473-2]
[10] Byard RW. Changing trends in suicides using helium or nitrogen – a 15‑year study. J Forensic Leg Med. 2018;58:6‑8. [DOI: 10.1016/j.jflm.2018.04.007]
[11] Smędra A, Szustowski S, Jurczyk AP, Klemm J, Szram S, Berent J. Suicidal asphyxiation by using helium – two case reports. Arch Med Sadowej Kryminol. 2015;65(1):37‑46. [DOI: 10.5114/amsik.2015.51605]
[12] Austin A, Winskog C, van den Heuvel C, Byard RW. Recent trends in suicides utilizing helium. J Forensic Sci. 2011;56(3):649‑51. [DOI: 10.1111/j.1556-4029.2011.01723.x]
[13] Grassberger M, Krauskopf A. Suicidal asphyxiation with helium: report of three cases. Wien Klin Wochenschr. 2007;119(9‑10):323‑5. [DOI: 10.1007/s00508-007-0785-4]
[14] Howard MO, Hall MT, Edwards JD, Vaughn MG, Perron BE, Winecker RE. Suicide by asphyxiation due to helium inhalation. Am J Forensic Med Pathol. 2011;32(1):61‑70. [DOI: 10.1097/paf.0b013e3181ed7a2d]
[15] Potenza S, Tavone AM, Dossena C, Marella GL. Inhalation of helium in plastic bag suffocation with suicidal purpose: observation and differences of two cases. Med Leg J. 2025;93(Suppl 1):35‑38. [DOI: 10.1177/00258172211010377]
[16] Sinyor M, Williams M, Vincent M, Schaffer A, Yip PSF, Gunnell D. Suicide deaths by gas inhalation in Toronto: an observational study of emerging methods of suicide. J Affect Disord. 2019;243:226‑31. [DOI: 10.1016/j.jad.2018.09.017]
[17] van den Hondel KE, Punt P, Dorn T, Ceelen M, Aarts F, van der Zande D, et al. Suicide by helium inhalation in the Netherlands between 2012 and 2019. Forensic Sci Int. 2021;318:110566. [DOI: 10.1016/j.forsciint.2020.110566]
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