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Vol. 14 No. 1 (2024)

Bahman 2024

The Impact of Oral Probiotics on Laboratory Parameters in Patients With Alcohol Toxicity: A Single-blinded Intervention Study

  • Mahnaz Tajdari
  • Farbod Amiri
  • Mitra Rahimi
  • Laya Ohadi
  • Fariba Ghorbani
  • Shahin Shadnia
  • Peyman Erfan Talab Evini

International Journal of Medical Toxicology and Forensic Medicine, Vol. 14 No. 1 (2024), 4 Bahman 2024
https://doi.org/10.32598/ijmtfm.v14i1.43374 Published: 02/04/2024

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Abstract

Background: Alcohol toxicity is a significant medical emergency with implications for patient management and outcomes. This single-blinded randomized intervention study investigated the effects of oral probiotics on various laboratory parameters in patients with acute alcohol toxicity.
Methods: A total of 30 eligible patients were randomly assigned to either the control (placebo) or intervention (oral probiotics) group.
Results: While the study did not reveal a significant impact on the length of hospital stay (LOHS), it did demonstrate notable improvements in laboratory variables, including pH, serum glutathione level, serum vitamin B6 level, and O2 saturation, in the probiotic group.
Conclusion: These findings suggest the potential benefits of probiotics in mitigating certain aspects of alcohol toxicity.

Keywords:
  • Oral probiotics
  • Alcohol toxicity
  • Laboratory parameters
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How to Cite

Tajdari, M., Amiri, F., Rahimi, M., Ohadi, L., Ghorbani, F., Shadnia, S., & Talab Evini, P. E. (2024). The Impact of Oral Probiotics on Laboratory Parameters in Patients With Alcohol Toxicity: A Single-blinded Intervention Study. International Journal of Medical Toxicology and Forensic Medicine, 14(1). https://doi.org/10.32598/ijmtfm.v14i1.43374
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References

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Jung SJ, Hwang JH, Park EO, Lee SO, Chung YJ, Chung MJ, et al. Regulation of Alcohol and Acetaldehyde Metabolism by a Mixture of Lactobacillus and Bifidobacterium Species in Human. Nutrients [Internet]. 2021 Jun 1 [cited 2023 Sep 8];13(6). Available from: https://pubmed.ncbi.nlm.nih.gov/34070917/

Jung SJ, Hwang JH, Park EO, Lee SO, Chung YJ, Chung MJ, et al. Regulation of Alcohol and Acetaldehyde Metabolism by a Mixture of Lactobacillus and Bifidobacterium Species in Human. Nutrients [Internet]. 2021 Jun 1 [cited 2023 Sep 8];13(6). Available from: https://pubmed.ncbi.nlm.nih.gov/34070917/

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