Successful Treatment of Acute Aluminum Phosphide Poisoning by Aloe Vera Syrup: A Case Report
International Journal of Medical Toxicology and Forensic Medicine,
Vol. 11 No. 2 (2021),
15 June 2021
,
Page 33016
https://doi.org/10.32598/ijmtfm.v11i2.33016
Abstract
Background: Aluminum phosphide, known as rice pill in Iran, is a very effective pesticide for commercial and industrial use. The high lethality of Aluminum phosphide is due to Phosphine gas (PH3) which is released by its reaction with water. One of the most important properties of aluminum phosphide, which despite being very lethal to almost all living creatures, still makes it one of the most widely used pesticides, is its very high yield, ease of use, and, most importantly, the absence of residues in products after application; while its exposure to the human body is associated with high mortality.
Case Presentation: In this article, we reported the successful treatment of rice pill-induced poisoning in a 30-year-old man using a novel approach. Accordingly, we used sodium bicarbonate (50 ccs) and aloe vera syrup (1-2 L), followed by olive oil (150 cc olive oil was given every 2 hours).
Conclusion: While numerous studies recommend observing patient conditions as the treatment approach, our presented case was a successful experience of treating acute aluminum phosphide poisoning.
- Aluminum phosphide, Poisoning, Aloe vera
How to Cite
References
2. Moghadamnia AA. An update on toxicology of aluminum phosphide. DARU journal of Pharmaceutical Sciences. 2012 Dec 1;20(1):25.
3. Singh S, Bhalla A. Aluminum phosphide poisoning. Journal of Mahatma Gandhi Institute of Medical Sciences. 2015 Jan 1;20(1):15.
4. Hasabo1 G. Aluminum Phosphide, A Serious killer in Egypt.
5. Vikrant S, Gupta D, Singh M. Epidemiology and outcome of acute kidney injury from a tertiary care hospital in India. Saudi Journal of Kidney Diseases and Transplantation. 2018 Jul 1;29(4):956.
6. Etemadi-Aleagha A, Akhgari M, Iravani FS. Aluminum phosphide poisoning-related deaths in Tehran, Iran, 2006 to 2013. Medicine. 2015 Sep;94(38).
7. Alinejad S, Zamani N, Abdollahi M, Mehrpour O. A narrative review of acute adult poisoning in Iran. Iranian journal of medical sciences. 2017 Jul;42(4):327.
8. Sulaj Z, Drishti A, Çeko I, Gashi A, Vyshka G. Fatal aluminum phosphide poisonings in Tirana (Albania), 2009–2013. DARU Journal of Pharmaceutical Sciences. 2015 Dec;23(1):8.
9. Aronson, J. K. “A worldwide yearly survey of new data in adverse drug reactions. Vol. 33.” (2011): 669-690.
10. Hashemi-Domeneh B, Zamani N, Hassanian-Moghaddam H, Rahimi M, Shadnia S, Erfantalab P, Ostadi A. A review of aluminium phosphide poisoning and a flowchart to treat it. Archives of Industrial Hygiene and Toxicology. 2016 Sep 1;67(3):183-93.
11. Ahmad A, Imran Z, Asad U. THE TREND OF ACUTE POISONING CASES PRESENTED TO THE EMERGENCY DEPARTMENT OF A TEACHING HOSPITAL.
12. Sciuto AM, Wong BJ, Martens ME, Hoard-Fruchey H, Perkins MW. Phosphine toxicity: a story of disrupted mitochondrial metabolism. Annals of the New York Academy of Sciences. 2016 Jun;1374(1):41.
13. Yan H, Xiang P, Zhang S, Shen B, Shen M. Diagnosis of aluminum phosphide poisoning using a new analytical approach: forensic application to a lethal intoxication. International journal of legal medicine. 2017 Jul 1;131(4):1001-7.
14. Gümüş O, Demir U, Hekimoğlu Y, Aşırdizer M, Etli Y, Kartal E. A case who died due to the suicidal intake of aluminum phosphide. Cumhuriyet Tıp Dergisi. 2017 Mar 1;39(1):458-65.
15. Mashayekhian M, Hassanian‐Moghaddam H, Rahimi M, Zamani N, Aghabiklooei A, Shadnia S. Elevated Carboxyhaemoglobin Concentrations by Pulse CO‐Oximetry is Associated with Severe Aluminium Phosphide Poisoning. Basic & clinical pharmacology & toxicology. 2016.
16. Mirakbari SM. Hot charcoal vomitus in aluminum phosphide poisoning-A case report of internal thermal reaction in aluminum phosphide poisoning and review of literature. Indian journal of anaesthesia. 2015 Jul;59(7):433.
17. Hugar BS, Praveen S, Hosahally JS, Kainoor S, Shetty AR. Gastrointestinal hemorrhage in aluminum phosphide poisoning. Journal of forensic sciences. 2015 Jan;60:S261-3.
18. Mehrpour O, Gurjar M. Cardiogenic shock: The main cause of mortality in acute aluminum phosphide poisoning. Indian Journal of Critical Care Medicine. 2017 Apr 1;21(4):246-7.
19. Karimani A, Mohammadpour AH, Zirak MR, Rezaee R, Megarbane B, Tsatsakis A, Karimi G. Antidotes for aluminum phosphide poisoning–An update. Toxicology reports. 2018 Jan 1;5:1053-9.
20. Rayat Dost E, Foroughian M, Shakeri M, Shakeri H, Abiri S. Saving from Fatal Effect of Aluminum Phosphide (Rice Tablet): a Case Report. AMBIENT SCIENCE. 2019;6(1):40-2.
21. Singh S, Dilawari JB, Vashist R, Malhotra HS, Sharma BK. Aluminium phosphide ingestion. Br Med J (Clin Res Ed) 1985; 290(6475): 1110-11.
22. Karimi, Reza, Taheri Hassan. Report of two successful treatment of rice poisoning. Journal of Babol University of Medical Sciences. ۱۳۸۶; ۹ (۱): ۵۸-۶۲.
23. Siwach SB, Singh P, Ahlawat S, Dua A, Sharma D. Serum & tissue magnesium content in patients of aluminium phosphide poisoning and critical evaluation of high dose magnesium sulphate therapy in reducing mortality. J Assoc Physicians India 1994; 42(8): 670.
24. Schonwald S. Medical toxicology, a synopsis and study guide, 1st ed, Lippincott, Williams and Wilkins 2001; pp: 731-2.
25. Rhbrtarmsry M., O. Pour Reza, T. Zarkam, Palyzkar Mary, Moosavian enlightened Sydamyn. Evaluation of rice poisoned patients. Journal of Guilan University of Medical Sciences: Winter 2005, Volume 14, Number 56; From page 42 to page 47.
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