Efficacy of Lofexidine in the Outpatient Management of Tramadol Withdrawal Syndrome Lofexidine in management of tramadol withdrawal
International Journal of Medical Toxicology and Forensic Medicine,
Vol. 10 No. 4 (2020),
16 November 2020
,
Page 32270
https://doi.org/10.32598/ijmtfm.v10i4.32270
Abstract
Tramadol is recognized as an opioid with non-opiate properties. It has a low affinity for opioid receptors and prevents reabsorption of norepinephrine and serotonin at synapses. It also increases the level of Gamma Aminobutyric Acid (GABA) in the central nervous system [1, 2]. Tramadol is an analgesic for patients suffering from moderate to severe pain [1]. In addition, previous studies have shown that tramadol abuse and suicidal attempts have increased in Iran [3, 4].
- Lofexidine; Tramadol; Substance Withdrawal Syndrome
How to Cite
References
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