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  3. Vol. 10 No. 4 (2020): International Journal of Medical Toxicology and Forensic Medicine
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Vol. 10 No. 4 (2020)

November 2020

Risperidone-Induced Erythema Multiforme Minor: A Case Report

  • Sina Negintaji
  • Reza Bidaki
  • Javad Zare Kamali
  • Fatemeh Saghafi
  • Maryam Naseri Bafrouie
  • Nilofar Tabaei Zadeh
  • Hossein Azadi

International Journal of Medical Toxicology and Forensic Medicine, Vol. 10 No. 4 (2020), 16 November 2020 , Page 28119
https://doi.org/10.32598/ijmtfm.v10i4.28119 Published: 12/14/2020

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Abstract

Erythema Multiforme (EM) is a hypersensitivity reaction that can be triggered by an infection or particular medications. Erythema multiforme minor (EM minor) represents localized skin lesions with minimal or no mucosal involvement. Only a few case of EM associated with risperidone are found in the scientific literature. In this case report, the administration of the risperidone resulted in the rapid appearance of skin lesions. Erythematous lesions were recovered upon discontinuation of the drug and no new skin lesion was observed. A 52-year-old male patient was admitted to the psychiatry hospital because of developing schizophrenic symptoms. At the time of admission, risperidone was added to her previous drug regimen. Two weeks later, the patient returned with a complaint of progressively increasing rashes over his body. The patient was diagnosed with EM minor. The prescribed risperidone was discontinued due to its side-effect profile and the patient’s drug regimen was changed entirely to the olanzapine, haloperidol, and topical clobetasol. At one month follow up visit, his skin lesions were satisfactorily controlled.

Keywords:
  • Erythema multiforme
  • Skin lesions
  • Antipsychotic medication
  • Risperidone
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How to Cite

Negintaji, S., Bidaki, R., Zare Kamali, J., Saghafi, F., Naseri Bafrouie, M., Tabaei Zadeh, N., & Azadi, H. (2020). Risperidone-Induced Erythema Multiforme Minor: A Case Report. International Journal of Medical Toxicology and Forensic Medicine, 10(4), 28119. https://doi.org/10.32598/ijmtfm.v10i4.28119
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References

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