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Vol. 10 No. 4 (2020)

November 2020

Guillain-Barre Syndrome Due to Tramadol

  • Ali Banagozar Mohammadi
  • Ali Ostadi
  • Maryam Paeezi
  • Babak Mostafazadeh

International Journal of Medical Toxicology and Forensic Medicine, Vol. 10 No. 4 (2020), 16 November 2020 , Page 27146
https://doi.org/10.32598/ijmtfm.v10i4.27146 Published: 12/22/2020

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Abstract

Tramadol is a powerful prescription medication used for pain relief of varying intensities. Tramadol was initially produced in Germany to alleviate postsurgical and chronic pains. We describe a case of a 22-year-old male with no past medical history who took tramadol for the second time and then had a tonic-clonic seizure episode that worsened the weakness of his inferior limbs and followed by loss of consciousness. According to physical examination, clinical and paraclinical tests, he was diagnosed with Guillain-Barre syndrome. After treatment with intravenous immunoglobulin, he was improved and discharged 9 days after treatment. He was recommended to continue physiotherapy. The relation between tramadol using and Guillain-Barre syndrome development is unknown but it can be due to reactive oxygen species generation.

 

Keywords:
  • Tramadol
  • Gillian barre syndrome
  • Reactive oxygen species
  • Seizure
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How to Cite

Banagozar Mohammadi, A., Ostadi, A., Paeezi, M., & Mostafazadeh, B. (2020). Guillain-Barre Syndrome Due to Tramadol. International Journal of Medical Toxicology and Forensic Medicine, 10(4), 27146. https://doi.org/10.32598/ijmtfm.v10i4.27146
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