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Vol. 19 No. 2 (2025)

March 2025

Anti-seizure Medication Induced Cognitive Impairment in Children with Epilepsy: A Narrative Review Antiseizure medication and cognitive impairment

  • Negin Armide
  • Meisam Babaei

Iranian Journal of Child Neurology, Vol. 19 No. 2 (2025), 11 March 2025 , Page 9-25
https://doi.org/10.22037/ijcn.v19i2.46371 Published: 2025-03-11

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Abstract

Several circumstances, including the etiology of epilepsy, its early onset, recurrent seizures, and the use of anti-seizure medications (ASMs), can lead to cognitive impairment in people with epilepsy. Studies indicate that the etiology of epilepsy may be more closely associated with cognitive problems than the ASMs. However, considering long-term treatment in pediatrics and their developing nervous systems, it is critical to understand the cognitive effects of each anti-seizure medication. Significant methodological challenges exist in studying the cognitive effects of ASMs. Accordingly, this review aims to give a broad overview of recent studies on cognitive impairment caused by first- and second-generation ASMs

Keywords:
  • Antiseizure medication
  • Cognition
  • Children.
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How to Cite

Armide, N., & Babaei, M. (2025). Anti-seizure Medication Induced Cognitive Impairment in Children with Epilepsy: A Narrative Review: Antiseizure medication and cognitive impairment. Iranian Journal of Child Neurology, 19(2), 9–25. https://doi.org/10.22037/ijcn.v19i2.46371
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