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Vol. 20 No. 1 (2026)

January 2026

Diagnostic Utility of Common Brain MRI Technique in Pediatric Epilepsy: A Cross-Sectional Study MRI Findings in Pediatric Epilepsy

  • Meisam Babaei
  • Maryam Tavakoli
  • Faeze Heidari

Iranian Journal of Child Neurology, Vol. 20 No. 1 (2026), 1 January 2026 , Page 25-33
https://doi.org/10.22037/ijcn.v20i1.46330 Published: 2026-01-01

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Abstract

Objectives:

Pediatric epilepsy is a neurological condition that could be associated with structural brain abnormalities. Although the common magnetic resonance imaging (MRI) technique is a standard tool for detecting these abnormalities, its diagnostic utility remains unclear compared to advanced neuroimaging techniques. This study aimed to evaluate the effectiveness of the common brain MRI technique in identifying structural lesions in pediatric epilepsy.

Materials & Methods: In this cross-sectional investigation, 337 patients with pediatric epilepsy underwent a common brain MRI. The scans were examined for abnormal lesions and assessed for their connections with neurological characteristics. Chi-square tests were used in statistical analysis to detect essential connections.

Results:

Brain MRI scans revealed abnormalities in 20.7% of patients. These abnormalities included white matter lesions (72%), gray matter lesions (22%), hippocampal lesions (12.8%), ventricular lesions (7%), and vascular lesions (2.8%). A significant relationship was found between abnormal neurological exam results and brain MRI findings (p < 0.001).

Conclusion:

While standard brain MRI can help identify structural abnormalities in pediatric epilepsy, it is not the most sensitive method, particularly compared to advanced neuroimaging techniques. Higher-resolution imaging and advanced modalities such as diffusion tensor imaging (DTI) and functional MRI (fMRI) may enhance diagnostic accuracy and improve outcomes in pediatric epilepsy management

Keywords:
  • Pediatric, epilepsy, Etiology, Conventional MRI
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How to Cite

Babaei, M., Tavakoli, M., & Heidari, F. (2026). Diagnostic Utility of Common Brain MRI Technique in Pediatric Epilepsy: A Cross-Sectional Study: MRI Findings in Pediatric Epilepsy. Iranian Journal of Child Neurology, 20(1), 25–33. https://doi.org/10.22037/ijcn.v20i1.46330
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References

Zhang D, Liu X, Deng X. Genetic basis of pediatric epilepsy syndromes. Exp Ther Med [Internet]. 2017 May 1 [cited 2024 Sep 4];13(5):2129. Available from: /pmc/articles/PMC5443213/

(UK) NGA. Magnetic resonance imaging scan to detectrelevant abnormalities in people with epilepsy. Magnetic resonance imaging scan to detectrelevant abnormalities in people with epilepsy: Epilepsies in children, young people and adults: Evidence review A [Internet]. 2022 [cited 2024 Sep 4]; Available from: https://www.ncbi.nlm.nih.gov/books/NBK581149/

Florkow MC, Willemsen K, Mascarenhas V V., Oei EHG, van Stralen M, Seevinck PR. Magnetic Resonance Imaging Versus Computed Tomography for Three‐Dimensional Bone Imaging of Musculoskeletal Pathologies: A Review. Journal of Magnetic Resonance Imaging [Internet]. 2022 Jul 1 [cited 2024 Sep 4];56(1):11. Available from: /pmc/articles/PMC9305220/

Alam-Eldeen MH, Hasan NMA. Assessment of the diagnostic reliability of brain CT and MRI in pediatric epilepsy patients. The Egyptian Journal of Radiology and Nuclear Medicine. 2015 Dec 1;46(4):1129–41.

Durá-Travé T, Yoldi-Petri ME, Esparza-Estaún J, Gallinas-Victoriano F, Aguilera-Albesa S, Sagastibelza-Zabaleta A, et al. Central Nervous System Findings on Magnetic Resonance Imaging in Children with Epilepsy. Neuroimaging - Clinical Applications [Internet]. 2012 Mar 9 [cited 2024 Sep 4]; Available from: https://www.intechopen.com/chapters/31414

Gaillard WD, Chiron C, Helen Cross J, Simon Harvey A, Kuzniecky R, Hertz-Pannier L, et al. Guidelines for imaging infants and children with recent-onset epilepsy. Epilepsia [Internet]. 2009 Sep 1 [cited 2024 Sep 4];50(9):2147–53. Available from: https://onlinelibrary.wiley.com/doi/full/10.1111/j.1528-1167.2009.02075.x

Goyal M, Bangert BA, Lewin JS, Cohen ML, Robinson S. High-resolution MRI Enhances Identification of Lesions Amenable to Surgical Therapy in Children with Intractable Epilepsy. Epilepsia [Internet]. 2004 Aug 1 [cited 2024 Sep 4];45(8):954–9. Available from: https://onlinelibrary.wiley.com/doi/full/10.1111/j.0013-9580.2004.39403.x

Carlson HL, Laliberté C, Brooks BL, Hodge J, Kirton A, Bello-Espinosa L, et al. Reliability and variability of diffusion tensor imaging (DTI) tractography in pediatric epilepsy. Epilepsy and Behavior [Internet]. 2014 Aug 1 [cited 2024 Sep 4];37:116–22. Available from: http://www.epilepsybehavior.com/article/S1525505014002261/fulltext

Amirsalari S, Saburi A, Hadi R, Mirmohammad SM. Magnetic Resonance Imaging (MRI) Findings in Epileptic Children and its Relation with Clinical and Demographic Findings. Pediatric Research 2011 70:5 [Internet]. 2011 Nov [cited 2024 Sep 4];70(5):146–146. Available from: https://www.nature.com/articles/pr2011371

Basiratnia R, Rezaei M, Mottaghi M, Naghshineh F. Imaging of Pediatric Epilepsy. Iranian Journal of Radiology 2014 11:30th Iranian Congress of Radiology [Internet]. 2014 Mar 1 [cited 2024 Sep 4];11(30th Iranian Congress of Radiology). Available from: https://brieflands.com/articles/ijradiology-77841

Ozateş M, Acar M, Tibbi FBT ve GR, 2003 undefined. Cranial MRI findings in epileptic children. europepmc.org [Internet]. [cited 2024 Sep 4]; Available from: https://europepmc.org/article/med/14730950

Lundberg S, Eeg-Olofsson O, Raininko R, Eeg-Olofsson KE. Hippocampal Asymmetries and White Matter Abnormalities on MRI in Benign Childhood Epilepsy with Centrotemporal Spikes. Epilepsia [Internet]. 1999 Dec 1 [cited 2024 Sep 4];40(12):1808–15. Available from: https://onlinelibrary.wiley.com/doi/full/10.1111/j.1528-1157.1999.tb01603.x

Shaikh Z, Torres A, Takeoka M. Neuroimaging in Pediatric Epilepsy. Brain Sci [Internet]. 2019 Aug 1 [cited 2024 Sep 4];9(8). Available from: https://pubmed.ncbi.nlm.nih.gov/31394851/

Raafat BM, Alotaibi A, Alfaqih W, Alotaibi Y, Alotaibi J, Alghoraibi F, et al. The effectiveness of MRI in the management of pediatric epilepsy at a tertiary care hospital in Taif, Saudi Arabia. J Radiat Res Appl Sci. 2024 Jun 1;17(2):100916.

Hajalioghli P. MRI Findings in Children Presenting with Epilepsy. Iranian Journal of Radiology 2014 11:30th Iranian Congress of Radiology [Internet]. 2014 Mar 1 [cited 2024 Sep 4];11(30th Iranian Congress of Radiology). Available from: https://brieflands.com/articles/ijradiology-75457

Juhász C, John F. Utility of MRI, PET, and ictal SPECT in presurgical evaluation of non-lesional pediatric epilepsy. Seizure. 2020 Apr 1;77:15–28.

Goodman AM, Szaflarski JP. Recent Advances in Neuroimaging of Epilepsy. Neurotherapeutics [Internet]. 2021 Apr 1 [cited 2024 Sep 11];18(2):811. Available from: /pmc/articles/PMC8423975/

Shaikh Z, Torres A, Takeoka M. Neuroimaging in Pediatric Epilepsy. Brain Sci [Internet]. 2019 Aug 1 [cited 2024 Sep 11];9(8). Available from: /pmc/articles/PMC6721420/

Elmi AM, Ibrahim AA, Hassan MS, Osman FAO, Çelik C, Dirie AM, et al. Magnetic Resonance Imaging Findings and Their Association with Electroencephalographic Data in Children with Epilepsy at Tertiary Care Hospital in Mogadishu Somalia. Int J Gen Med [Internet]. 2024 Jan [cited 2024 Sep 4];17:253. Available from: /pmc/articles/PMC10821646/

Samia P, Odero N, Njoroge M, Ochieng S, Mavuti J, Waa S, et al. Magnetic Resonance Imaging Findings in Childhood Epilepsy at a Tertiary Hospital in Kenya. Front Neurol [Internet]. 2021 Feb 12 [cited 2024 Sep 4];12. Available from: https://pubmed.ncbi.nlm.nih.gov/33643201/

Winston GP, Micallef C, Kendell BE, Bartlett PA, Williams EJ, Burdett JL, et al. The value of repeat neuroimaging for epilepsy at a tertiary referral centre: 16 years of experience. Epilepsy Res. 2013 Aug 1;105(3):349–55.

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