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Vol. 18 No. 4 (2024)

September 2024

Giant Primary Epidural Extraskeletal Ewing Sarcoma in Cervical Spine in Infant Previously Evaluated for Neurodevelopmental Delay: Case Report and Review of the Literature

  • mehran beiraghi toosi
  • Sousan Mousavi
  • ehsan keykhosravi
  • Hamid Rezaee
  • Paria Dehghanian
  • farnoosh ebrahimzadeh
  • amin tavallayi

Iranian Journal of Child Neurology, Vol. 18 No. 4 (2024), 29 September 2024 , Page 127-134
https://doi.org/10.22037/ijcn.v18i4.29422 Published: 2024-09-29

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Abstract

Ewing sarcoma (ES) is a highly malignant tumor that originates from bones, especially long bones. ESarising from the epidural extramedullary space is highly unlikely, especially the cervical region. There have been only 6 cases of cervical epidural extraskeletal Ewing sarcoma (EEES) in children reported in the literature all of whom were older than 7-years-old. Out of 7 cases, including the one mentioned in this study, 4 were male (57%). Herein, we report a 1.5-year-old girl who presented with quadriparesis without cognitive impairment and had initially undergone metabolic disorder evaluation. The spine MRI revealed a mass in C2-T6 region and she underwent a biopsy of the tumor via laminectomy.

Microscopic examination confirms a diagnosis of ES based on immunohistochemistry. This is the first literature that presents an infant with EEES.

Keywords:
  • Ewing sarcoma
  • quadriparesis
  • infant
  • developmental delay..
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How to Cite

beiraghi toosi, mehran, Mousavi, S., keykhosravi, ehsan, Rezaee, H., Dehghanian, P., ebrahimzadeh, farnoosh, & tavallayi, amin. (2024). Giant Primary Epidural Extraskeletal Ewing Sarcoma in Cervical Spine in Infant Previously Evaluated for Neurodevelopmental Delay: Case Report and Review of the Literature. Iranian Journal of Child Neurology, 18(4), 127–134. https://doi.org/10.22037/ijcn.v18i4.29422
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