A dermatopathic Juvenile Dermatomyositis; An Unexpected Case in Childhood
Iranian Journal of Child Neurology,
Vol. 14 No. 3 (2020),
28 June 2020
Juvenile dermatomyositis (JDM) is a rare idiopathic inflammatory disease which usually presents with skin rashes along with muscle weakness. We report a case of JDM in a 10- year-old girl with no skin manifestations.
She was presented with progressive muscle weakness and fatigue. Further laboratory investigation along with a muscle biopsy confirmed the diagnosis of Adermathopathic Juvenile Dermatomyositis. The patient was treated with intravenous immunoglobulin, corticosteroids, methotrexate, hydroxychloroquine, pamidronate, and Rituximab.
Following treatment, patients symptoms subsided and she gained normal muscular strength over the course of a year.
- Juvenile Dermatomyositis
Rider LG, Lindsley CB, Miller FW. Chapter 26 - Juvenile Dermatomyositis. Textbook of Pediatric Rheumatology (Seventh Edition).Philadelphia: W.B. Saunders; 2016. p. 351-83. e18.
Rose MR, Kissel JT, Bickley LS, Griggs RC. Sustained myoglobinuria: the presenting manifestation of dermatomyositis. Neurology. 1996;47(1):119-23.
Wagner B, Kagan-Hallet KS, Russell IJ. Concomitant Presentation of Adermatopathic Dermatomyositis, Statin Myopathy,Fibromyalgia Syndrome, Piriformis Muscle
Myofascial Pain Syndrome, and Diabetic Neuropathy. Journal of Musculoskeletal Pain. 2003;11(2):25-30.
Bohan A, Peter JB. Polymyositis and dermatomyositis (first of two parts). The New England journal of medicine. 1975;292(7):344-7.
Bohan A, Peter JB. Polymyositis and dermatomyositis (second of two parts). The New England journal of medicine. 1975;292(8):403-7
.6. Troyanov Y, Targoff IN, Payette MP, Raynauld JP, Chartier S, Goulet JR, et al. Redefining dermatomyositis: a description of new diagnostic criteria that differentiate pure dermatomyositis from overlap myositis with dermatomyositis features. Medicine. 2014;93(24):318-32.
Levine TD. Rituximab in the treatment of dermatomyositis: an open-label pilot study. Arthritis and rheumatism. 2005;52(2):601-7.
Cooper MA, Willingham DL, Brown DE, French AR, Shih FF, White AJ. Rituximab for the treatment of juvenile dermatomyositis: a report of four pediatric patients. Arthritis and rheumatism. 2007;56(9):3107-11.
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