• Register
  • Login

Iranian Journal of Child Neurology

  • Home
  • About
    • About the Journal
    • Indexing & Abstracting
    • Submissions
    • Editorial Team
    • Privacy Statement
    • Contact
  • Current
  • Archives
  • Announcements
Advanced Search
  1. Home
  2. Archives
  3. Vol. 13 No. 3 (2019): summer
  4. Research Article

Vol. 13 No. 3 (2019)

July 2019

Is There Any Relationship between Vitamin D Deficiency and Gross Motor Development in12-Month-Old Children?

  • Reza Tavakolizadeh
  • Maryam Ardalani
  • Ghazal Shariatpanahi
  • Seyed Yousef Mojtahedi
  • Azadeh Sayarifard

Iranian Journal of Child Neurology, Vol. 13 No. 3 (2019), 1 July 2019 , Page 55-60
https://doi.org/10.22037/ijcn.v13i3.17910 Published: 2019-07-01

  • View Article
  • Download
  • Cite
  • References
  • Statastics
  • Share

Abstract

Objective: we aimed to estimate possible relationship between vitamin D deficiency and gross motor developmental milestones in Iranian children.

Material and Methods: In this cross sectional study, 186 one-year old healthy children referring to one children hospital in Tehran were studied. The gross motor developmental milestone of children and their serum vitamin D concentration were evaluated.

Results: A total of 186 children, males 92 (49.5%) were studied. 24 children (12.9%) could sit, 40 (21.5%) could stand and 122 (65.6%) could walk. Vitamin D was sufficient in 148 children (79.6%), insufficient in 32 (17.2%) and deficient in 6 (3.2%).  Sufficient vitamin D was significantly correlated with walking ability (p<0.001, OR=3.9, 95%CI=1.9-8.4). 

Conclusion: Considering the significant correlation between vitamin D deficiency and gross motor developmental milestones in this population of children, it can be recommended that children referring with gross motor developmental delay need to be thoroughly evaluated for vitamin D deficiency. 

Keywords:
  • Vitamin D
  • gross motor development
  • children
  • PDF

How to Cite

Tavakolizadeh, R., Ardalani, M., Shariatpanahi, G., Yousef Mojtahedi, S., & Sayarifard, A. (2019). Is There Any Relationship between Vitamin D Deficiency and Gross Motor Development in12-Month-Old Children?. Iranian Journal of Child Neurology, 13(3), 55–60. https://doi.org/10.22037/ijcn.v13i3.17910
  • ACM
  • ACS
  • APA
  • ABNT
  • Chicago
  • Harvard
  • IEEE
  • MLA
  • Turabian
  • Vancouver
  • Endnote/Zotero/Mendeley (RIS)
  • BibTeX

References

Fleet JC, Schoch RD. Molecular mechanisms for regulation of intestinal calcium absorption by vitamin D and other factors. Critical reviews in clinical laboratory sciences. 2010;47(4):181-95.

Braegger C, Campoy C, Colomb V, Decsi T, Domellof M, Fewtrell M, et al. Vitamin D in the healthy European paediatric population. Journal of pediatric gastroenterology and nutrition. 2013;56(6):692-701.

Christakos S, DeLuca HF. Minireview: vitamin D: is there a role in extraskeletal health? Endocrinology. 2011;152(8):2930-6.

Bouillon R, Norman AW, Lips P. Vitamin D deficiency. N Engl J Med. 2007;357(19):1980-1.

Wang TJ, Pencina MJ, Booth SL, Jacques PF, Ingelsson E, Lanier K, et al. Vitamin D deficiency and risk of cardiovascular disease. Circulation. 2008;117(4):503-11.

Lee JY, So T-Y, Thackray J. A review on vitamin d deficiency treatment in pediatric patients. The Journal of Pediatric Pharmacology and Therapeutics. 2013;18(4):277-91.

Misra M, Pacaud D, Petryk A, Collett-Solberg PF, Kappy M. Vitamin D deficiency in children and its management: review of current knowledge and recommendations. Pediatrics. 2008;122(2):398-417.

Moe SM. Disorders involving calcium, phosphorus, and magnesium. Primary Care: Clinics in Office Practice. 2008;35(2):215-37.

Trivedi DP, Doll R, Khaw KT. Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial. Bmj. 2003;326(7387):469.

Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism. 2011;96(7):1911-30.

Holick MF. Vitamin D deficiency. New England Journal of Medicine. 2007;357(3):266-81.

Zhou C, Assem M, Tay JC, Watkins PB, Blumberg B, Schuetz EG, et al. Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. The Journal of clinical investigation. 2006;116(6):1703-12.

Motlaghzadeh Y, Sayarifard F, Allahverdi B, Rabbani A, Setoodeh A, Sayarifard A, et al. Assessment of Vitamin D Status and Response to Vitamin D3 in Obese and Non-Obese Iranian Children. J Trop Pediatr. 2016 Aug;62(4):269-75. doi: 10.1093/tropej/fmv091. Epub 2016 Mar 19.

Mohammadian S, Mortezazadeh R, Zaeri H, Vakili MA. Relationship between 25-hydroxy vitamin-D and obesity in 2-7 years old children referred to a paediatric hospital in Iran. Journal of clinical and diagnostic research: JCDR. 2014;8(9):PC06.

Agarwal A, Gulati D, Rath S, Walia M. Rickets: a cause of delayed walking in toddlers. The Indian Journal of Pediatrics. 2009;76(3):269-72.

Soliman A, De Sanctis V, Adel A, El Awwa A, Bedair S. Clinical, biochemical and radiological manifestations of severe vitamin d deficiency in adolescents versus children: response to therapy. Georgian medical news. 2012(210):58-64.

Ladhani S, Srinivasan L, Buchanan C, Allgrove J. Presentation of vitamin D deficiency. Archives of disease in childhood. 2004;89(8):781-4.

Siddiqui TS, Rai MI. Presentation and predisposing factors of nutritional rickets in children of Hazara Division. J Ayub Med Coll Abbottabad. 2005;17(3):29-32.

Callaghan AL, Moy R, Booth IW, Debelle G, Shaw NJ. Incidence of symptomatic vitamin D deficiency. Archives of disease in childhood. 2006;91(7):606-7.

Soliman AT, El-Dabbagh M, Adel A, Al Ali M, Bedair EMA, ElAlaily RK. Clinical responses to a mega-dose of vitamin D3 in infants and toddlers with vitamin D deficiency rickets. Journal of tropical pediatrics. 2009:fmp040.

Michie C, Bangalore S. Managing vitamin D deficiency in children. London journal of primary care. 2010;3(1):31-6.

  • Abstract Viewed: 228 times

Download Statastics

  • Linkedin
  • Twitter
  • Facebook
  • Google Plus
  • Telegram

Developed By

Open Journal Systems
  • Home
  • Archives
  • Submissions
  • About the Journal
  • Editorial Team
  • Contact
Powered by OJSPlus