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  3. Vol. 5 No. 3 (2012): Summer
  4. Original Article

ISSN: 2008-2258

Summer
Vol. 5 No. 3 (2012)

Microscopic Enteritis; clinical features and correlations with symptoms

  • Touran Shahraki
  • Kamran Rostami
  • Mansour Shahraki
  • Justine Bold
  • Mihai Danciu
  • David Al Dulaimi
  • Vincenzo Villanacci
  • Gabrio Bassotti

Gastroenterology and Hepatology from Bed to Bench, Vol. 5 No. 3 (2012),
https://doi.org/10.22037/ghfbb.v5i3.285 Published 1 July 2012

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Abstract

Aim: To assess the clinical characteristic of CD as well as correlation of symptoms and the degrees of intestinal mucosal lesions in Iranian children.

Background: Microscopic Enteritis (Marsh 0-II) is associated with malabsorption.

Patients and methods: From August 2005 to September 2009, 111 cases with malabsorption and classical gastrointestinal symptoms were evaluated.

Results: The mean (±SD) age of children with CD was 4.9±3.5 years (range, 6 month - 16 years) and the mean duration of symptoms was 8 ± 20.5 months. 50 cases (45%) were female and 61 cases (55%) were male. The most common clinical presentation was failure to thrive in 72%, chronic diarrhea in 65.8% and Iron deficiency anemia in 59.5%. Sensitivity of EMA was 100% in patients with Marsh IIIb and Marsh IIIc. EMA was also positive in 77% of cases with Marsh 0, 18% in Marsh I, 44% in Marsh II and 81.8% in patients with Marsh IIIa.

Conclusion: Histopathology did not reflect the severity of gluten sensitivity. This would suggest that the degree of intestinal mucosal damage might not be a reliable prognostic factor. Significant symptoms can be present with minor histological change on biopsy.

Keywords:
  • Coeliac disease
  • Serology
  • Histology
  • Macroscopic enteritis
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How to Cite

Shahraki, T., Rostami, K., Shahraki, M., Bold, J., Danciu, M., Al Dulaimi, D., Villanacci, V., & Bassotti, G. (2012). Microscopic Enteritis; clinical features and correlations with symptoms. Gastroenterology and Hepatology from Bed to Bench, 5(3). https://doi.org/10.22037/ghfbb.v5i3.285
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GHFBB journal is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).

Print ISSN: 2008-2258
Online ISSN: 2008-4234

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