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  3. Vol. 16 No. 2 (2023): Vol 16, No 2 (2023): Spring
  4. Review Article

Vol. 16 No. 2 (2023)

April 2023

Collagenous colitis associated with novel sprue-like intestinal diseases

  • Hugh James Freeman

Gastroenterology and Hepatology from Bed to Bench, Vol. 16 No. 2 (2023), 21 April 2023
https://doi.org/10.22037/ghfbb.v16i2.2698 Published: 2023-04-21

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Abstract

Almost a half-century ago, an unusual and distinct form of colitis was first recognized, collagenous colitis, characterized by sub-epithelial trichrome-positive deposits having the ultrastructural features of collagen. Later, other reports documented more extensive collagenous dis-ease in these patients, sometimes in the stomach and small bowel, a close linkage with other forms of microscopic colitis and its association with celiac and other immune-mediated diseases. Moreover, emerging genetic methods permitted large studies of collagenous colitis to complement these intriguing clinical and pathological studies.  Finally, recent and related studies have further demonstrated these immune-based forms of colitis, with new sprue-like intestinal diseases caused by novel medications, recently detected viral infections and vaccinations.    

Keywords:
  • Celiac disease
  • colitis
  • collagenous colitis
  • collagenous sprue
  • sprue-like intestinal disease
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How to Cite

Freeman, H. J. (2023). Collagenous colitis associated with novel sprue-like intestinal diseases. Gastroenterology and Hepatology from Bed to Bench, 16(2). https://doi.org/10.22037/ghfbb.v16i2.2698
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